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A novel norditerpenoid alkaloid from Aconitum macrorhynchum.
J Asian Nat Prod Res. 2009 Aug; 11(8):728-31.JA

Abstract

A novel norditerpenoid alkaloid, macrorhynine C (1), together with three known compounds, was isolated from Aconitum macrorhynchum. The structure of the new alkaloid was elucidated on the basis of spectral analyses as (1alpha,6alpha,16beta)-3-hydroxy-8-acetyloxy-13-hydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-19-ene-aconitan-14-yl 4-methoxybenzoate (1). The novel compound was found to contain the rare C(19) = N azomethine group. Compounds 2-4 were obtained from this species for the first time.

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Authors+Show Affiliations

Yang LJ
Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, China.
Luo YP
No affiliation info available
Chen W
No affiliation info available
Zhao JF
No affiliation info available
Yang XD
No affiliation info available
Li L
No affiliation info available

MeSH

AconitumAlkaloidsDiterpenesDrugs, Chinese HerbalMolecular StructureNuclear Magnetic Resonance, BiomolecularPlant RootsStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20183315

Citation

Yang, Li-Juan, et al. "A Novel Norditerpenoid Alkaloid From Aconitum Macrorhynchum." Journal of Asian Natural Products Research, vol. 11, no. 8, 2009, pp. 728-31.
Yang LJ, Luo YP, Chen W, et al. A novel norditerpenoid alkaloid from Aconitum macrorhynchum. J Asian Nat Prod Res. 2009;11(8):728-31.
Yang, L. J., Luo, Y. P., Chen, W., Zhao, J. F., Yang, X. D., & Li, L. (2009). A novel norditerpenoid alkaloid from Aconitum macrorhynchum. Journal of Asian Natural Products Research, 11(8), 728-31. https://doi.org/10.1080/10286020903029223
Yang LJ, et al. A Novel Norditerpenoid Alkaloid From Aconitum Macrorhynchum. J Asian Nat Prod Res. 2009;11(8):728-31. PubMed PMID: 20183315.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A novel norditerpenoid alkaloid from Aconitum macrorhynchum. AU - Yang,Li-Juan, AU - Luo,Yi-Ping, AU - Chen,Wen, AU - Zhao,Jing-Feng, AU - Yang,Xiao-Dong, AU - Li,Liang, PY - 2010/2/26/entrez PY - 2010/2/26/pubmed PY - 2010/3/20/medline SP - 728 EP - 31 JF - Journal of Asian natural products research JO - J Asian Nat Prod Res VL - 11 IS - 8 N2 - A novel norditerpenoid alkaloid, macrorhynine C (1), together with three known compounds, was isolated from Aconitum macrorhynchum. The structure of the new alkaloid was elucidated on the basis of spectral analyses as (1alpha,6alpha,16beta)-3-hydroxy-8-acetyloxy-13-hydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-19-ene-aconitan-14-yl 4-methoxybenzoate (1). The novel compound was found to contain the rare C(19) = N azomethine group. Compounds 2-4 were obtained from this species for the first time. SN - 1477-2213 UR - https://www.unboundmedicine.com/medline/citation/20183315/A_novel_norditerpenoid_alkaloid_from_Aconitum_macrorhynchum_ L2 - https://www.tandfonline.com/doi/full/10.1080/10286020903029223 DB - PRIME DP - Unbound Medicine ER -