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Physiological and immune responses of Zhikong Scallop Chlamys farreri to the acute viral necrobiotic virus infection.
Fish Shellfish Immunol. 2010 Jul; 29(1):42-8.FS

Abstract

The Zhikong Scallop, Chlamys farreri, is one of the most important bivalve mollusks cultured in northern China. However, mass mortality of the cultured C. farreri has posed a serious threat to the maricultural industry in recent years. Acute Viral Necrobiotic Virus (AVNV) is believed as an important etiological agent causing the scallop mass mortalities. To understand the mechanism behind the AVNV associated scallop disease and mortality, we assessed the physiological and immune responses of C. farreri to the virus infection using oxygen consumption rate, ammonium-nitrogen excretion rate, hemocyte copper, zinc superoxide dismutase gene expression, and plasma superoxide dismutase activity and alkaline phosphatase activity as indicators. Scallops challenged by AVNV at 25 degrees C developed typical disease signs 2 days after virus injection. Before the disease manifested, scallop oxygen consumption and NH4+-N excretion rates rose and then fell back. Real-time PCR revealed that the hemocyte cytosol Cu, Zn SOD gene expression was upregulated followed by recovery. The plasma SOD activity, however, augmented consistently following virus injection. Moreover, plasma AKP activity first lowered and then elevated gradually to the highest level at 24 h post virus injection. Scallops challenged by AVNV at 17 degrees C neither developed notable disease nor showed obvious responses that could be associated with the virus infection. While the results suggested a correlation between the elevated seawater temperature and the AVNV infection associated C. farreri mortalities, they also indicated that the viral infection provoked multiple physiological and immune responses in the host scallops.

Authors+Show Affiliations

Institute of Oceanology, Chinese Academy of Sciences, 7 Nanhai Road, Qingdao 266071, China; East China Sea Fisheries Research Institute, Chinese Academy of Fishery Science, Shanghai 200090, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20188840

Citation

Tang, Baojun, et al. "Physiological and Immune Responses of Zhikong Scallop Chlamys Farreri to the Acute Viral Necrobiotic Virus Infection." Fish & Shellfish Immunology, vol. 29, no. 1, 2010, pp. 42-8.
Tang B, Liu B, Wang X, et al. Physiological and immune responses of Zhikong Scallop Chlamys farreri to the acute viral necrobiotic virus infection. Fish Shellfish Immunol. 2010;29(1):42-8.
Tang, B., Liu, B., Wang, X., Yue, X., & Xiang, J. (2010). Physiological and immune responses of Zhikong Scallop Chlamys farreri to the acute viral necrobiotic virus infection. Fish & Shellfish Immunology, 29(1), 42-8. https://doi.org/10.1016/j.fsi.2010.02.019
Tang B, et al. Physiological and Immune Responses of Zhikong Scallop Chlamys Farreri to the Acute Viral Necrobiotic Virus Infection. Fish Shellfish Immunol. 2010;29(1):42-8. PubMed PMID: 20188840.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Physiological and immune responses of Zhikong Scallop Chlamys farreri to the acute viral necrobiotic virus infection. AU - Tang,Baojun, AU - Liu,Baozhong, AU - Wang,Xiaomei, AU - Yue,Xin, AU - Xiang,Jianhai, Y1 - 2010/02/25/ PY - 2009/09/14/received PY - 2010/02/12/revised PY - 2010/02/19/accepted PY - 2010/3/2/entrez PY - 2010/3/2/pubmed PY - 2010/9/3/medline SP - 42 EP - 8 JF - Fish & shellfish immunology JO - Fish Shellfish Immunol. VL - 29 IS - 1 N2 - The Zhikong Scallop, Chlamys farreri, is one of the most important bivalve mollusks cultured in northern China. However, mass mortality of the cultured C. farreri has posed a serious threat to the maricultural industry in recent years. Acute Viral Necrobiotic Virus (AVNV) is believed as an important etiological agent causing the scallop mass mortalities. To understand the mechanism behind the AVNV associated scallop disease and mortality, we assessed the physiological and immune responses of C. farreri to the virus infection using oxygen consumption rate, ammonium-nitrogen excretion rate, hemocyte copper, zinc superoxide dismutase gene expression, and plasma superoxide dismutase activity and alkaline phosphatase activity as indicators. Scallops challenged by AVNV at 25 degrees C developed typical disease signs 2 days after virus injection. Before the disease manifested, scallop oxygen consumption and NH4+-N excretion rates rose and then fell back. Real-time PCR revealed that the hemocyte cytosol Cu, Zn SOD gene expression was upregulated followed by recovery. The plasma SOD activity, however, augmented consistently following virus injection. Moreover, plasma AKP activity first lowered and then elevated gradually to the highest level at 24 h post virus injection. Scallops challenged by AVNV at 17 degrees C neither developed notable disease nor showed obvious responses that could be associated with the virus infection. While the results suggested a correlation between the elevated seawater temperature and the AVNV infection associated C. farreri mortalities, they also indicated that the viral infection provoked multiple physiological and immune responses in the host scallops. SN - 1095-9947 UR - https://www.unboundmedicine.com/medline/citation/20188840/Physiological_and_immune_responses_of_Zhikong_Scallop_Chlamys_farreri_to_the_acute_viral_necrobiotic_virus_infection_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1050-4648(10)00069-0 DB - PRIME DP - Unbound Medicine ER -