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Relationship of retinal vascular tortuosity with the neuroretinal rim: the singapore malay eye study.
Invest Ophthalmol Vis Sci. 2010 Jul; 51(7):3736-41.IO

Abstract

PURPOSE.

To describe the association of retinal vascular tortuosity, measured quantitatively, with the neuroretinal rim.

METHODS.

A population-based, cross-sectional study was conducted in Malay persons aged 40 to 80 years residing in Singapore. Retinal vascular tortuosity was quantified by using a semiautomated, computer-assisted program assessing retinal fundus photographs, according to a standardized protocol. Optic disc measurements including disc area, rim area, and rim-to-disc area (RDA) ratio were obtained with a confocal scanning laser ophthalmoscope.

RESULTS.

In analyses adjusting for age, sex, spherical equivalent, and retinal vascular caliber, reduced arteriolar and venular tortuosity were associated with a decrease in global RDA ratio (P = 0.006 and P = 0.001, respectively). When compared with the arterioles, retinal venular tortuosity demonstrated a stronger association with RDA ratio. The temporal-inferior region of the neuroretinal rim was most strongly associated with retinal vascular tortuosity.

CONCLUSIONS.

Straighter retinal vessels were significantly associated with a thinning neuroretinal rim. These findings may provide additional insights into the geometric retinal vascular changes seen in early glaucomatous optic neuropathy.

Authors+Show Affiliations

Singapore Eye Research Institute, Singapore National Eye Center, Singapore.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20207964

Citation

Koh, Victor, et al. "Relationship of Retinal Vascular Tortuosity With the Neuroretinal Rim: the Singapore Malay Eye Study." Investigative Ophthalmology & Visual Science, vol. 51, no. 7, 2010, pp. 3736-41.
Koh V, Cheung CY, Zheng Y, et al. Relationship of retinal vascular tortuosity with the neuroretinal rim: the singapore malay eye study. Invest Ophthalmol Vis Sci. 2010;51(7):3736-41.
Koh, V., Cheung, C. Y., Zheng, Y., Wong, T. Y., Wong, W., & Aung, T. (2010). Relationship of retinal vascular tortuosity with the neuroretinal rim: the singapore malay eye study. Investigative Ophthalmology & Visual Science, 51(7), 3736-41. https://doi.org/10.1167/iovs.09-5008
Koh V, et al. Relationship of Retinal Vascular Tortuosity With the Neuroretinal Rim: the Singapore Malay Eye Study. Invest Ophthalmol Vis Sci. 2010;51(7):3736-41. PubMed PMID: 20207964.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationship of retinal vascular tortuosity with the neuroretinal rim: the singapore malay eye study. AU - Koh,Victor, AU - Cheung,Carol Yim-Lui, AU - Zheng,Yingfeng, AU - Wong,Tien Yin, AU - Wong,Wanling, AU - Aung,Tin, Y1 - 2010/03/05/ PY - 2010/3/9/entrez PY - 2010/3/9/pubmed PY - 2010/8/3/medline SP - 3736 EP - 41 JF - Investigative ophthalmology & visual science JO - Invest Ophthalmol Vis Sci VL - 51 IS - 7 N2 - PURPOSE. To describe the association of retinal vascular tortuosity, measured quantitatively, with the neuroretinal rim. METHODS. A population-based, cross-sectional study was conducted in Malay persons aged 40 to 80 years residing in Singapore. Retinal vascular tortuosity was quantified by using a semiautomated, computer-assisted program assessing retinal fundus photographs, according to a standardized protocol. Optic disc measurements including disc area, rim area, and rim-to-disc area (RDA) ratio were obtained with a confocal scanning laser ophthalmoscope. RESULTS. In analyses adjusting for age, sex, spherical equivalent, and retinal vascular caliber, reduced arteriolar and venular tortuosity were associated with a decrease in global RDA ratio (P = 0.006 and P = 0.001, respectively). When compared with the arterioles, retinal venular tortuosity demonstrated a stronger association with RDA ratio. The temporal-inferior region of the neuroretinal rim was most strongly associated with retinal vascular tortuosity. CONCLUSIONS. Straighter retinal vessels were significantly associated with a thinning neuroretinal rim. These findings may provide additional insights into the geometric retinal vascular changes seen in early glaucomatous optic neuropathy. SN - 1552-5783 UR - https://www.unboundmedicine.com/medline/citation/20207964/Relationship_of_retinal_vascular_tortuosity_with_the_neuroretinal_rim:_the_singapore_malay_eye_study_ DB - PRIME DP - Unbound Medicine ER -