TY - JOUR T1 - Outcomes in diabetic versus nondiabetic patients who present with acute myocardial infarction and are treated with drug-eluting stents. AU - Syed,Asmir I, AU - Ben-Dor,Itsik, AU - Li,Yanlin, AU - Collins,Sara D, AU - Gonzalez,Manuel A, AU - Gaglia,Michael A, AU - Maluenda,Gabriel, AU - Delhaye,Cedric, AU - Wakabayashi,Kohei, AU - Bonello,Laurant, AU - De Labriolle,Axel, AU - Belle,Loic, AU - Torguson,Rebecca, AU - Xue,Zhenyi, AU - Kaneshige,Kimberly, AU - Bernardo,Nelson, AU - Satler,Lowell F, AU - Kent,Kenneth M, AU - Suddath,William O, AU - Pichard,Augusto D, AU - Lindsay,Joseph, AU - Waksman,Ron, PY - 2009/09/21/received PY - 2009/11/08/revised PY - 2009/11/08/accepted PY - 2010/3/10/entrez PY - 2010/3/10/pubmed PY - 2010/3/30/medline SP - 819 EP - 25 JF - The American journal of cardiology JO - Am J Cardiol VL - 105 IS - 6 N2 - Patients with diabetes mellitus (DM) are at a greater risk of mortality and cardiovascular events after percutaneous coronary intervention than those without DM. We aimed to determine whether differences exist in the long-term mortality of patients with versus without DM who present with acute myocardial infarction and receive drug-eluting stents. Data were collected on 161 patients with and 395 without DM referred for primary percutaneous coronary intervention for acute myocardial infarction and treated with drug-eluting stents. The patients with cardiac arrest or cardiogenic shock were excluded. The 1-year major cardiac event (MACE) rates, defined as death, Q-wave myocardial infarction, or target lesion revascularization, were compared between the 2 groups. The patients with DM were sicker at baseline. The MACE rates at 1 year were significantly increased in those with DM compared to those without DM. This was primarily driven by all-cause mortality. No differences in Q-wave myocardial infarction, target lesion revascularization, stent thrombosis, type of drug-eluting stents used, or procedure-related renal failure were seen. No differences were found in death or MACE rates at 1 year after adjusting for age, gender, race, systemic hypertension, peripheral artery disease, and a history of chronic renal failure between the 2 groups (weighted log-rank statistic, p = 0.37 and p = 0.37, respectively). In patients presenting with acute myocardial infarction, those with DM were sicker than those without DM. In conclusion, after correction for co-morbid conditions, no difference was seen in the 1-year MACE or death rates between those with and without DM who presented with acute myocardial infarction and were treated with drug-eluting stents. SN - 1879-1913 UR - https://www.unboundmedicine.com/medline/citation/20211325/Outcomes_in_diabetic_versus_nondiabetic_patients_who_present_with_acute_myocardial_infarction_and_are_treated_with_drug_eluting_stents_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9149(09)02683-6 DB - PRIME DP - Unbound Medicine ER -