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Generalized necrobiotic xanthogranuloma successfully treated with lenalidomide.
J Drugs Dermatol. 2010 Mar; 9(3):273-6.JD

Abstract

Necrobiotic xanthogranuloma (NXG) presents a therapeutic challenge to clinicians. Generalized NXG has limited treatment options. A patient presented to the authors with generalized NXG associated with monoclonal gammopathy of unknown significance (MGUS), a plasma cell dyscrasia considered to be a precursor to multiple myeloma. The patient was treated with lenalidomide, a derivative of thalidomide with efficacy in treatment of multiple myeloma. Resolution of paraproteinemia was associated with resolution of NXG.

Authors+Show Affiliations

Department of Dermatology, University of Texas Medical School at Houston, Houston, TX, USA.No affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

20232591

Citation

Silapunt, Sirunya, and Susan Y. Chon. "Generalized Necrobiotic Xanthogranuloma Successfully Treated With Lenalidomide." Journal of Drugs in Dermatology : JDD, vol. 9, no. 3, 2010, pp. 273-6.
Silapunt S, Chon SY. Generalized necrobiotic xanthogranuloma successfully treated with lenalidomide. J Drugs Dermatol. 2010;9(3):273-6.
Silapunt, S., & Chon, S. Y. (2010). Generalized necrobiotic xanthogranuloma successfully treated with lenalidomide. Journal of Drugs in Dermatology : JDD, 9(3), 273-6.
Silapunt S, Chon SY. Generalized Necrobiotic Xanthogranuloma Successfully Treated With Lenalidomide. J Drugs Dermatol. 2010;9(3):273-6. PubMed PMID: 20232591.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Generalized necrobiotic xanthogranuloma successfully treated with lenalidomide. AU - Silapunt,Sirunya, AU - Chon,Susan Y, PY - 2010/3/18/entrez PY - 2010/3/18/pubmed PY - 2010/4/16/medline SP - 273 EP - 6 JF - Journal of drugs in dermatology : JDD JO - J Drugs Dermatol VL - 9 IS - 3 N2 - Necrobiotic xanthogranuloma (NXG) presents a therapeutic challenge to clinicians. Generalized NXG has limited treatment options. A patient presented to the authors with generalized NXG associated with monoclonal gammopathy of unknown significance (MGUS), a plasma cell dyscrasia considered to be a precursor to multiple myeloma. The patient was treated with lenalidomide, a derivative of thalidomide with efficacy in treatment of multiple myeloma. Resolution of paraproteinemia was associated with resolution of NXG. SN - 1545-9616 UR - https://www.unboundmedicine.com/medline/citation/20232591/Generalized_necrobiotic_xanthogranuloma_successfully_treated_with_lenalidomide_ L2 - http://www.diseaseinfosearch.org/result/7560 DB - PRIME DP - Unbound Medicine ER -