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Iron status of Zairean pregnant women with and without serological markers of hepatitis B virus infection.
J Trop Med Hyg 1991; 94(2):104-9JT

Abstract

We assessed the iron status of 203 Zairean pregnant women: 38 with chronic hepatitis B virus (HBV) infection (HBsAg(+)), 94 with antibodies to the surface antigen (Anti-HBs(+)) and 71 without HBV markers (HBsAg(-)/Anti-HBs(-)). Participants, age range 15-42 years and parity 1-12, were recruited from Mama Yemo Hospital in summer 1983. Haemoglobin (Hb), serum iron, total iron binding capacity and transferrin saturation (TS) were determined by standard techniques and serum ferritin (FERR) by radioimmunoassay. To rule out inflammation and/or infection which increase FERR levels, C-reactive protein (CRP) and alpha 1-acid glycoprotein (AGP) were also measured. There was no significant difference in the mean levels of any of the haematologic measurements, FERR, CRP and AGP between the three HBV groups. Women who took iron supplements had slightly higher mean levels of Hb but not serum FERR or TS than those who did not. Women with inflammation and identical HBV markers had higher mean FERR levels than those without inflammation. Neither the prevalence of anaemia, which varied between 32 and 35%, nor that of iron deficiency, which varied between 52 and 59%, differed significantly between the three groups of women. We conclude that in pregnant women, chronic asymptomatic HBV infection is not associated with a lower prevalence of iron deficiency and/or anaemia.

Authors+Show Affiliations

Department of Pediatrics, LSU Medical Center, New Orleans 70112.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2023285

Citation

Kuvibidila, S, et al. "Iron Status of Zairean Pregnant Women With and Without Serological Markers of Hepatitis B Virus Infection." The Journal of Tropical Medicine and Hygiene, vol. 94, no. 2, 1991, pp. 104-9.
Kuvibidila S, Mbela K, Masabi M, et al. Iron status of Zairean pregnant women with and without serological markers of hepatitis B virus infection. J Trop Med Hyg. 1991;94(2):104-9.
Kuvibidila, S., Mbela, K., Masabi, M., & Mbendi, N. (1991). Iron status of Zairean pregnant women with and without serological markers of hepatitis B virus infection. The Journal of Tropical Medicine and Hygiene, 94(2), pp. 104-9.
Kuvibidila S, et al. Iron Status of Zairean Pregnant Women With and Without Serological Markers of Hepatitis B Virus Infection. J Trop Med Hyg. 1991;94(2):104-9. PubMed PMID: 2023285.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Iron status of Zairean pregnant women with and without serological markers of hepatitis B virus infection. AU - Kuvibidila,S, AU - Mbela,K, AU - Masabi,M, AU - Mbendi,N, PY - 1991/4/1/pubmed PY - 1991/4/1/medline PY - 1991/4/1/entrez KW - Africa KW - Africa South Of The Sahara KW - Biology KW - Developing Countries KW - Diseases KW - Examinations And Diagnoses KW - French Speaking Africa KW - Hemic System KW - Hemoglobin Level--changes KW - Hepatic Effects KW - Ingredients And Chemicals KW - Inorganic Chemicals KW - Iron--administraction and dosage KW - Laboratory Examinations And Diagnoses KW - Measurement KW - Metals KW - Middle Africa KW - Physiology KW - Pregnancy KW - Prevalence KW - Reproduction KW - Research Methodology KW - Serum Iron Level KW - Viral Diseases KW - Zaire SP - 104 EP - 9 JF - The Journal of tropical medicine and hygiene JO - J Trop Med Hyg VL - 94 IS - 2 N2 - We assessed the iron status of 203 Zairean pregnant women: 38 with chronic hepatitis B virus (HBV) infection (HBsAg(+)), 94 with antibodies to the surface antigen (Anti-HBs(+)) and 71 without HBV markers (HBsAg(-)/Anti-HBs(-)). Participants, age range 15-42 years and parity 1-12, were recruited from Mama Yemo Hospital in summer 1983. Haemoglobin (Hb), serum iron, total iron binding capacity and transferrin saturation (TS) were determined by standard techniques and serum ferritin (FERR) by radioimmunoassay. To rule out inflammation and/or infection which increase FERR levels, C-reactive protein (CRP) and alpha 1-acid glycoprotein (AGP) were also measured. There was no significant difference in the mean levels of any of the haematologic measurements, FERR, CRP and AGP between the three HBV groups. Women who took iron supplements had slightly higher mean levels of Hb but not serum FERR or TS than those who did not. Women with inflammation and identical HBV markers had higher mean FERR levels than those without inflammation. Neither the prevalence of anaemia, which varied between 32 and 35%, nor that of iron deficiency, which varied between 52 and 59%, differed significantly between the three groups of women. We conclude that in pregnant women, chronic asymptomatic HBV infection is not associated with a lower prevalence of iron deficiency and/or anaemia. SN - 0022-5304 UR - https://www.unboundmedicine.com/medline/citation/2023285/Iron_status_of_Zairean_pregnant_women_with_and_without_serological_markers_of_hepatitis_B_virus_infection_ L2 - http://www.diseaseinfosearch.org/result/3332 DB - PRIME DP - Unbound Medicine ER -