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Phytochemical and antimicrobial activity of Swietenia mahagoni crude methanolic seed extract.
Trop Biomed 2009; 26(3):274-9TB

Abstract

The present study was designed to evaluate the antibacterial activities of Swietenia mahagoni crude methanolic (SMCM) seed extract. The antimicrobial activity of the oily extract against Gram-positive, Gram-negative, yeast and fungus strains was evaluated based on the inhibition zone using disc diffusion assay, minimal inhibition concentration (MIC) and minimal bactericidal concentration (MBC) values. The crude extract was subjected to various phytochemicals analysis. The demonstrated qualitative phytochemical tests exhibited the presences of common phytocompounds including alkaloids, terpenoids, antraquinones, cardiac glycosides, saponins, and volatile oils as major active constituents. The SMCM seed extract had inhibitory effects on the growth of Candida albicans, Staphylococcus aureus, Pseudomonas aeroginosa, Streptococcus faecalis and Proteus mirabillase and illustrated MIC and MBC values ranging from 25 mg/ml to 50 mg/ml.

Authors+Show Affiliations

Centre for Drug Research, University Sains Malaysia, 11800 Penang, Malaysia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20237441

Citation

Sahgal, G, et al. "Phytochemical and Antimicrobial Activity of Swietenia Mahagoni Crude Methanolic Seed Extract." Tropical Biomedicine, vol. 26, no. 3, 2009, pp. 274-9.
Sahgal G, Ramanathan S, Sasidharan S, et al. Phytochemical and antimicrobial activity of Swietenia mahagoni crude methanolic seed extract. Trop Biomed. 2009;26(3):274-9.
Sahgal, G., Ramanathan, S., Sasidharan, S., Mordi, M. N., Ismail, S., & Mansor, S. M. (2009). Phytochemical and antimicrobial activity of Swietenia mahagoni crude methanolic seed extract. Tropical Biomedicine, 26(3), pp. 274-9.
Sahgal G, et al. Phytochemical and Antimicrobial Activity of Swietenia Mahagoni Crude Methanolic Seed Extract. Trop Biomed. 2009;26(3):274-9. PubMed PMID: 20237441.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phytochemical and antimicrobial activity of Swietenia mahagoni crude methanolic seed extract. AU - Sahgal,G, AU - Ramanathan,S, AU - Sasidharan,S, AU - Mordi,M N, AU - Ismail,S, AU - Mansor,S M, PY - 2010/3/19/entrez PY - 2010/3/20/pubmed PY - 2011/3/30/medline SP - 274 EP - 9 JF - Tropical biomedicine JO - Trop Biomed VL - 26 IS - 3 N2 - The present study was designed to evaluate the antibacterial activities of Swietenia mahagoni crude methanolic (SMCM) seed extract. The antimicrobial activity of the oily extract against Gram-positive, Gram-negative, yeast and fungus strains was evaluated based on the inhibition zone using disc diffusion assay, minimal inhibition concentration (MIC) and minimal bactericidal concentration (MBC) values. The crude extract was subjected to various phytochemicals analysis. The demonstrated qualitative phytochemical tests exhibited the presences of common phytocompounds including alkaloids, terpenoids, antraquinones, cardiac glycosides, saponins, and volatile oils as major active constituents. The SMCM seed extract had inhibitory effects on the growth of Candida albicans, Staphylococcus aureus, Pseudomonas aeroginosa, Streptococcus faecalis and Proteus mirabillase and illustrated MIC and MBC values ranging from 25 mg/ml to 50 mg/ml. SN - 0127-5720 UR - https://www.unboundmedicine.com/medline/citation/20237441/Phytochemical_and_antimicrobial_activity_of_Swietenia_mahagoni_crude_methanolic_seed_extract_ L2 - http://www.msptm.org/files/274_-_279_Sasidharan_S.pdf DB - PRIME DP - Unbound Medicine ER -