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High dose chloral hydrate sedation for children undergoing CT.
J Comput Assist Tomogr 1991 May-Jun; 15(3):467-9JC

Abstract

Chloral hydrate is commonly used to sedate children before CT. However, no prospective study has been published of the safety and efficacy of chloral hydrate at high dose levels for children undergoing CT. We define high dose levels of oral chloral hydrate to be 80-100 mg/kg, with a maximum total dose of 2 g. High dose chloral hydrate sedation was administered orally to 295 children for 326 CT examinations. Adverse reactions occurred in 7% of the children, with vomiting being the most common (4.3% of children). Hyperactivity and respiratory symptoms each occurred in less than 2% of children. Prolonged sedation (greater than 2 h) was not encountered in our series. Sedation was successful in producing motion free CT examinations, so that in 303 (93%) of the cases, no repeat CT scans were needed. We conclude that high dose oral chloral hydrate provides safe and effective sedation for children undergoing CT.

Authors+Show Affiliations

Department of Radiology, St. Christopher's Hospital for Children, Philadelphia, PA 19134-1095.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2026812

Citation

Greenberg, S B., et al. "High Dose Chloral Hydrate Sedation for Children Undergoing CT." Journal of Computer Assisted Tomography, vol. 15, no. 3, 1991, pp. 467-9.
Greenberg SB, Faerber EN, Aspinall CL. High dose chloral hydrate sedation for children undergoing CT. J Comput Assist Tomogr. 1991;15(3):467-9.
Greenberg, S. B., Faerber, E. N., & Aspinall, C. L. (1991). High dose chloral hydrate sedation for children undergoing CT. Journal of Computer Assisted Tomography, 15(3), pp. 467-9.
Greenberg SB, Faerber EN, Aspinall CL. High Dose Chloral Hydrate Sedation for Children Undergoing CT. J Comput Assist Tomogr. 1991;15(3):467-9. PubMed PMID: 2026812.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - High dose chloral hydrate sedation for children undergoing CT. AU - Greenberg,S B, AU - Faerber,E N, AU - Aspinall,C L, PY - 1991/5/1/pubmed PY - 1991/5/1/medline PY - 1991/5/1/entrez SP - 467 EP - 9 JF - Journal of computer assisted tomography JO - J Comput Assist Tomogr VL - 15 IS - 3 N2 - Chloral hydrate is commonly used to sedate children before CT. However, no prospective study has been published of the safety and efficacy of chloral hydrate at high dose levels for children undergoing CT. We define high dose levels of oral chloral hydrate to be 80-100 mg/kg, with a maximum total dose of 2 g. High dose chloral hydrate sedation was administered orally to 295 children for 326 CT examinations. Adverse reactions occurred in 7% of the children, with vomiting being the most common (4.3% of children). Hyperactivity and respiratory symptoms each occurred in less than 2% of children. Prolonged sedation (greater than 2 h) was not encountered in our series. Sedation was successful in producing motion free CT examinations, so that in 303 (93%) of the cases, no repeat CT scans were needed. We conclude that high dose oral chloral hydrate provides safe and effective sedation for children undergoing CT. SN - 0363-8715 UR - https://www.unboundmedicine.com/medline/citation/2026812/High_dose_chloral_hydrate_sedation_for_children_undergoing_CT_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=2026812.ui DB - PRIME DP - Unbound Medicine ER -