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[Plasma levels of beta-endorphin in obese subjects with normal glucose tolerance test and in diabetics].
Recenti Prog Med. 1991 Jan; 82(1):1-3.RP

Abstract

Forty obese subjects with normal glucose tolerance test (NGTT) thirteen diabetic obese subjects and sixteen normal subjects were studied to evaluate the possible interactions between beta-endorphin (B-Ep) and glucose homeostasis. On the basis of baseline B-Ep levels, two subgroups were selected: one group with normal mean values of B-Ep (7.02 +/- 0.59 pmol/l); another group with elevated mean values of B-Ep (18.95 +/- 1.52 pmol/l). No differences between these subgroups were found as regards body mass index (BMI), insulin and glucagon levels. Normal B-Ep values were found in diabetic obese subjects. No significant correlation was found between B-Ep and BMI, insulin or glucagon. Considering that B-Ep is involved in eating behavior and on the basis of our results, we suggest that elevated B-Ep levels can be found only in those obese NGTT subjects whose obesity is probably related to an abnormal modulation of food intake, such as hyperphagia.

Authors+Show Affiliations

Donatelli M
Cattedra di Clinica medica I, Università, Palermo.
Terrizzi C
No affiliation info available
Russo V
No affiliation info available
Bucalo ML
No affiliation info available
Scarpinato A
No affiliation info available
Verga S
No affiliation info available
Puglisi S
No affiliation info available
Miceli G
No affiliation info available
Iraci T
No affiliation info available
Bompiani GD
No affiliation info available

MeSH

AdultBlood GlucoseDiabetes MellitusFemaleGlucagonGlucose Tolerance TestHumansInsulinMaleObesitybeta-Endorphin

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

ita

PubMed ID

2028070

Citation

Donatelli, M, et al. "[Plasma Levels of Beta-endorphin in Obese Subjects With Normal Glucose Tolerance Test and in Diabetics]." Recenti Progressi in Medicina, vol. 82, no. 1, 1991, pp. 1-3.
Donatelli M, Terrizzi C, Russo V, et al. [Plasma levels of beta-endorphin in obese subjects with normal glucose tolerance test and in diabetics]. Recenti Prog Med. 1991;82(1):1-3.
Donatelli, M., Terrizzi, C., Russo, V., Bucalo, M. L., Scarpinato, A., Verga, S., Puglisi, S., Miceli, G., Iraci, T., & Bompiani, G. D. (1991). [Plasma levels of beta-endorphin in obese subjects with normal glucose tolerance test and in diabetics]. Recenti Progressi in Medicina, 82(1), 1-3.
Donatelli M, et al. [Plasma Levels of Beta-endorphin in Obese Subjects With Normal Glucose Tolerance Test and in Diabetics]. Recenti Prog Med. 1991;82(1):1-3. PubMed PMID: 2028070.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Plasma levels of beta-endorphin in obese subjects with normal glucose tolerance test and in diabetics]. AU - Donatelli,M, AU - Terrizzi,C, AU - Russo,V, AU - Bucalo,M L, AU - Scarpinato,A, AU - Verga,S, AU - Puglisi,S, AU - Miceli,G, AU - Iraci,T, AU - Bompiani,G D, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 1 EP - 3 JF - Recenti progressi in medicina JO - Recenti Prog Med VL - 82 IS - 1 N2 - Forty obese subjects with normal glucose tolerance test (NGTT) thirteen diabetic obese subjects and sixteen normal subjects were studied to evaluate the possible interactions between beta-endorphin (B-Ep) and glucose homeostasis. On the basis of baseline B-Ep levels, two subgroups were selected: one group with normal mean values of B-Ep (7.02 +/- 0.59 pmol/l); another group with elevated mean values of B-Ep (18.95 +/- 1.52 pmol/l). No differences between these subgroups were found as regards body mass index (BMI), insulin and glucagon levels. Normal B-Ep values were found in diabetic obese subjects. No significant correlation was found between B-Ep and BMI, insulin or glucagon. Considering that B-Ep is involved in eating behavior and on the basis of our results, we suggest that elevated B-Ep levels can be found only in those obese NGTT subjects whose obesity is probably related to an abnormal modulation of food intake, such as hyperphagia. SN - 0034-1193 UR - https://www.unboundmedicine.com/medline/citation/2028070/[Plasma_levels_of_beta_endorphin_in_obese_subjects_with_normal_glucose_tolerance_test_and_in_diabetics]_ DB - PRIME DP - Unbound Medicine ER -