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[Plasma levels of beta-endorphin in obese subjects with normal glucose tolerance test and in diabetics].
Recenti Prog Med. 1991 Jan; 82(1):1-3.RP

Abstract

Forty obese subjects with normal glucose tolerance test (NGTT) thirteen diabetic obese subjects and sixteen normal subjects were studied to evaluate the possible interactions between beta-endorphin (B-Ep) and glucose homeostasis. On the basis of baseline B-Ep levels, two subgroups were selected: one group with normal mean values of B-Ep (7.02 +/- 0.59 pmol/l); another group with elevated mean values of B-Ep (18.95 +/- 1.52 pmol/l). No differences between these subgroups were found as regards body mass index (BMI), insulin and glucagon levels. Normal B-Ep values were found in diabetic obese subjects. No significant correlation was found between B-Ep and BMI, insulin or glucagon. Considering that B-Ep is involved in eating behavior and on the basis of our results, we suggest that elevated B-Ep levels can be found only in those obese NGTT subjects whose obesity is probably related to an abnormal modulation of food intake, such as hyperphagia.

Authors+Show Affiliations

Cattedra di Clinica medica I, Università, Palermo.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

ita

PubMed ID

2028070

Citation

Donatelli, M, et al. "[Plasma Levels of Beta-endorphin in Obese Subjects With Normal Glucose Tolerance Test and in Diabetics]." Recenti Progressi in Medicina, vol. 82, no. 1, 1991, pp. 1-3.
Donatelli M, Terrizzi C, Russo V, et al. [Plasma levels of beta-endorphin in obese subjects with normal glucose tolerance test and in diabetics]. Recenti Prog Med. 1991;82(1):1-3.
Donatelli, M., Terrizzi, C., Russo, V., Bucalo, M. L., Scarpinato, A., Verga, S., Puglisi, S., Miceli, G., Iraci, T., & Bompiani, G. D. (1991). [Plasma levels of beta-endorphin in obese subjects with normal glucose tolerance test and in diabetics]. Recenti Progressi in Medicina, 82(1), 1-3.
Donatelli M, et al. [Plasma Levels of Beta-endorphin in Obese Subjects With Normal Glucose Tolerance Test and in Diabetics]. Recenti Prog Med. 1991;82(1):1-3. PubMed PMID: 2028070.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Plasma levels of beta-endorphin in obese subjects with normal glucose tolerance test and in diabetics]. AU - Donatelli,M, AU - Terrizzi,C, AU - Russo,V, AU - Bucalo,M L, AU - Scarpinato,A, AU - Verga,S, AU - Puglisi,S, AU - Miceli,G, AU - Iraci,T, AU - Bompiani,G D, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 1 EP - 3 JF - Recenti progressi in medicina JO - Recenti Prog Med VL - 82 IS - 1 N2 - Forty obese subjects with normal glucose tolerance test (NGTT) thirteen diabetic obese subjects and sixteen normal subjects were studied to evaluate the possible interactions between beta-endorphin (B-Ep) and glucose homeostasis. On the basis of baseline B-Ep levels, two subgroups were selected: one group with normal mean values of B-Ep (7.02 +/- 0.59 pmol/l); another group with elevated mean values of B-Ep (18.95 +/- 1.52 pmol/l). No differences between these subgroups were found as regards body mass index (BMI), insulin and glucagon levels. Normal B-Ep values were found in diabetic obese subjects. No significant correlation was found between B-Ep and BMI, insulin or glucagon. Considering that B-Ep is involved in eating behavior and on the basis of our results, we suggest that elevated B-Ep levels can be found only in those obese NGTT subjects whose obesity is probably related to an abnormal modulation of food intake, such as hyperphagia. SN - 0034-1193 UR - https://www.unboundmedicine.com/medline/citation/2028070/[Plasma_levels_of_beta_endorphin_in_obese_subjects_with_normal_glucose_tolerance_test_and_in_diabetics]_ L2 - https://medlineplus.gov/obesity.html DB - PRIME DP - Unbound Medicine ER -