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Electrochemical incineration of diclofenac in neutral aqueous medium by anodic oxidation using Pt and boron-doped diamond anodes.
Chemosphere. 2010 Apr; 79(6):605-12.C

Abstract

The degradation of diclofenac, a common non-steroidal anti-inflammatory drug, in aqueous medium has been studied by anodic oxidation (AO) using an undivided cell with a Pt or boron-doped diamond (BDD) anode. Operating without pH regulation, AO with Pt acidifies the solution with precipitation of its protonated form, whereas using BDD, the solution becomes alkaline and only attains partial mineralization. Total incineration of low contents of the drug is feasible by AO with BDD in a neutral buffer medium of pH 6.5. Comparative treatment with Pt gives poor decontamination. The diclofenac decay always follows a pseudo first-order reaction. The increase in current for AO with BDD accelerates the degradative process, but decreases its efficiency. 2-Hydroxyphenylacetic acid, 2,5-dihydroxyphenylacetic acid, 2,6-dichloroaniline and 2,6-dichlorohydroquinone have been identified as aromatic intermediates. For AO with Pt, high amounts of malic, succinic, tartaric and oxalic acids are accumulated in the bulk and the N-derivatives produced are rapidly destroyed with loss of NH4+. When BDD is employed, some carboxylic acids are also accumulated in small extent, with a larger persistence of oxalic and oxamic acids. The process involves the formation of different N-derivatives that slowly release NH4+ and NO3(-) ions. Chloride ion is lost in all cases.

Authors+Show Affiliations

Laboratori d'Electroquímica de Materials i del Medi Ambient, Departament de Química Física, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1-11, 08028 Barcelona, Spain. brillas@ub.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20307900

Citation

Brillas, Enric, et al. "Electrochemical Incineration of Diclofenac in Neutral Aqueous Medium By Anodic Oxidation Using Pt and Boron-doped Diamond Anodes." Chemosphere, vol. 79, no. 6, 2010, pp. 605-12.
Brillas E, Garcia-Segura S, Skoumal M, et al. Electrochemical incineration of diclofenac in neutral aqueous medium by anodic oxidation using Pt and boron-doped diamond anodes. Chemosphere. 2010;79(6):605-12.
Brillas, E., Garcia-Segura, S., Skoumal, M., & Arias, C. (2010). Electrochemical incineration of diclofenac in neutral aqueous medium by anodic oxidation using Pt and boron-doped diamond anodes. Chemosphere, 79(6), 605-12. https://doi.org/10.1016/j.chemosphere.2010.03.004
Brillas E, et al. Electrochemical Incineration of Diclofenac in Neutral Aqueous Medium By Anodic Oxidation Using Pt and Boron-doped Diamond Anodes. Chemosphere. 2010;79(6):605-12. PubMed PMID: 20307900.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Electrochemical incineration of diclofenac in neutral aqueous medium by anodic oxidation using Pt and boron-doped diamond anodes. AU - Brillas,Enric, AU - Garcia-Segura,Sergi, AU - Skoumal,Marcel, AU - Arias,Conchita, Y1 - 2010/03/21/ PY - 2010/01/15/received PY - 2010/03/02/revised PY - 2010/03/02/accepted PY - 2010/3/24/entrez PY - 2010/3/24/pubmed PY - 2010/6/29/medline SP - 605 EP - 12 JF - Chemosphere JO - Chemosphere VL - 79 IS - 6 N2 - The degradation of diclofenac, a common non-steroidal anti-inflammatory drug, in aqueous medium has been studied by anodic oxidation (AO) using an undivided cell with a Pt or boron-doped diamond (BDD) anode. Operating without pH regulation, AO with Pt acidifies the solution with precipitation of its protonated form, whereas using BDD, the solution becomes alkaline and only attains partial mineralization. Total incineration of low contents of the drug is feasible by AO with BDD in a neutral buffer medium of pH 6.5. Comparative treatment with Pt gives poor decontamination. The diclofenac decay always follows a pseudo first-order reaction. The increase in current for AO with BDD accelerates the degradative process, but decreases its efficiency. 2-Hydroxyphenylacetic acid, 2,5-dihydroxyphenylacetic acid, 2,6-dichloroaniline and 2,6-dichlorohydroquinone have been identified as aromatic intermediates. For AO with Pt, high amounts of malic, succinic, tartaric and oxalic acids are accumulated in the bulk and the N-derivatives produced are rapidly destroyed with loss of NH4+. When BDD is employed, some carboxylic acids are also accumulated in small extent, with a larger persistence of oxalic and oxamic acids. The process involves the formation of different N-derivatives that slowly release NH4+ and NO3(-) ions. Chloride ion is lost in all cases. SN - 1879-1298 UR - https://www.unboundmedicine.com/medline/citation/20307900/Electrochemical_incineration_of_diclofenac_in_neutral_aqueous_medium_by_anodic_oxidation_using_Pt_and_boron_doped_diamond_anodes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0045-6535(10)00261-4 DB - PRIME DP - Unbound Medicine ER -