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Radial scars without atypia diagnosed at imaging-guided needle biopsy: how often is associated malignancy found at subsequent surgical excision, and do mammography and sonography predict which lesions are malignant?
AJR Am J Roentgenol. 2010 Apr; 194(4):1146-51.AA

Abstract

OBJECTIVE

The purposes of our study were to evaluate the surgical outcome of cases of radial scar without atypia diagnosed at imaging-guided percutaneous needle biopsy and to determine whether the mammographic and sonographic features are able to predict which lesions will be upgraded to malignancy at surgical excision.

MATERIALS AND METHODS

The records of 4,458 consecutive imaging-guided biopsies were retrospectively reviewed. Surgical excision results were available in 62 cases in which radial scar was the highest-risk lesion at stereotactically guided or sonographically guided biopsy. The mammographic and sonographic images and surgical findings were reviewed. The underestimation rate of malignancy of percutaneous biopsy was calculated. Differences in mammographic and sonographic appearances between radial scars with and without associated malignancy were evaluated using the Fisher's exact test.

RESULTS

The percutaneous malignancy underestimation rate was 8% (5/62): 9% (4/43) for sonography guided 14-gauge biopsies and 5% (1/19) for stereotactically guided 11-gauge vacuum-assisted biopsies (p = 1.000). Mammographic and sonographic appearances were not significantly different between radial scars with and those without associated malignancy.

CONCLUSION

A percutaneous diagnosis of a radial scar does not exclude associated malignancy at surgical excision. Mammographic and sonographic features of a lesion diagnosed as a radial scar at percutaneous imaging-guided biopsy do not predict which lesions will have associated malignancy at surgery. Therefore, all patients with percutaneous diagnosis of a radial scar should undergo surgical excision regardless of mammographic and sonographic appearances, until further criteria can be determined.

Authors+Show Affiliations

Institute of Radiology, Azienda Ospedaliero Universitaria, University of Udine, Via Colugna 50, Udine, UD 33100, Italy. annalinda33@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20308524

Citation

Linda, Anna, et al. "Radial Scars Without Atypia Diagnosed at Imaging-guided Needle Biopsy: How Often Is Associated Malignancy Found at Subsequent Surgical Excision, and Do Mammography and Sonography Predict Which Lesions Are Malignant?" AJR. American Journal of Roentgenology, vol. 194, no. 4, 2010, pp. 1146-51.
Linda A, Zuiani C, Furlan A, et al. Radial scars without atypia diagnosed at imaging-guided needle biopsy: how often is associated malignancy found at subsequent surgical excision, and do mammography and sonography predict which lesions are malignant? AJR Am J Roentgenol. 2010;194(4):1146-51.
Linda, A., Zuiani, C., Furlan, A., Londero, V., Girometti, R., Machin, P., & Bazzocchi, M. (2010). Radial scars without atypia diagnosed at imaging-guided needle biopsy: how often is associated malignancy found at subsequent surgical excision, and do mammography and sonography predict which lesions are malignant? AJR. American Journal of Roentgenology, 194(4), 1146-51. https://doi.org/10.2214/AJR.09.2326
Linda A, et al. Radial Scars Without Atypia Diagnosed at Imaging-guided Needle Biopsy: How Often Is Associated Malignancy Found at Subsequent Surgical Excision, and Do Mammography and Sonography Predict Which Lesions Are Malignant. AJR Am J Roentgenol. 2010;194(4):1146-51. PubMed PMID: 20308524.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Radial scars without atypia diagnosed at imaging-guided needle biopsy: how often is associated malignancy found at subsequent surgical excision, and do mammography and sonography predict which lesions are malignant? AU - Linda,Anna, AU - Zuiani,Chiara, AU - Furlan,Alessandro, AU - Londero,Viviana, AU - Girometti,Rossano, AU - Machin,Piernicola, AU - Bazzocchi,Massimo, PY - 2010/3/24/entrez PY - 2010/3/24/pubmed PY - 2010/5/7/medline SP - 1146 EP - 51 JF - AJR. American journal of roentgenology JO - AJR Am J Roentgenol VL - 194 IS - 4 N2 - OBJECTIVE: The purposes of our study were to evaluate the surgical outcome of cases of radial scar without atypia diagnosed at imaging-guided percutaneous needle biopsy and to determine whether the mammographic and sonographic features are able to predict which lesions will be upgraded to malignancy at surgical excision. MATERIALS AND METHODS: The records of 4,458 consecutive imaging-guided biopsies were retrospectively reviewed. Surgical excision results were available in 62 cases in which radial scar was the highest-risk lesion at stereotactically guided or sonographically guided biopsy. The mammographic and sonographic images and surgical findings were reviewed. The underestimation rate of malignancy of percutaneous biopsy was calculated. Differences in mammographic and sonographic appearances between radial scars with and without associated malignancy were evaluated using the Fisher's exact test. RESULTS: The percutaneous malignancy underestimation rate was 8% (5/62): 9% (4/43) for sonography guided 14-gauge biopsies and 5% (1/19) for stereotactically guided 11-gauge vacuum-assisted biopsies (p = 1.000). Mammographic and sonographic appearances were not significantly different between radial scars with and those without associated malignancy. CONCLUSION: A percutaneous diagnosis of a radial scar does not exclude associated malignancy at surgical excision. Mammographic and sonographic features of a lesion diagnosed as a radial scar at percutaneous imaging-guided biopsy do not predict which lesions will have associated malignancy at surgery. Therefore, all patients with percutaneous diagnosis of a radial scar should undergo surgical excision regardless of mammographic and sonographic appearances, until further criteria can be determined. SN - 1546-3141 UR - https://www.unboundmedicine.com/medline/citation/20308524/Radial_scars_without_atypia_diagnosed_at_imaging_guided_needle_biopsy:_how_often_is_associated_malignancy_found_at_subsequent_surgical_excision_and_do_mammography_and_sonography_predict_which_lesions_are_malignant L2 - https://www.ajronline.org/doi/10.2214/AJR.09.2326 DB - PRIME DP - Unbound Medicine ER -