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Visceral leishmaniasis: another HIV-associated opportunistic infection? Report of eight cases and review of the literature.
AIDS. 1991 Feb; 5(2):201-7.AIDS

Abstract

Visceral leishmaniasis (VL) is considered an opportunistic infection in immunocompromised patients. We review the clinical, laboratory, and therapeutic data in 63 patients (eight new cases and 55 cases reported in the literature) with Mediterranean VL (kala azar) and HIV-1 infection to determine whether VL should be considered an opportunistic infection in HIV-infected adults. We conclude that: (1) in areas where both leishmaniasis and HIV-1 infection are endemic, VL may be more frequent among HIV-infected adults; (2) in HIV-infected patients, the clinical picture did not differ significantly from classical kala azar, although it often ran a recurrent course, with resistance to antimonial therapy. We propose the inclusion of VL in the IVC-2 subgroup of the Centers for Disease Control (CDC) clinical classification of HIV-1 infection while prospective and larger studies further define whether there are clinical presentations that could justify adding VL to the list of opportunistic infections indicative of AIDS.

Authors+Show Affiliations

Hospital Son Dureta (Palma de Mallorca), Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2031693

Citation

Altés, J, et al. "Visceral Leishmaniasis: Another HIV-associated Opportunistic Infection? Report of Eight Cases and Review of the Literature." AIDS (London, England), vol. 5, no. 2, 1991, pp. 201-7.
Altés J, Salas A, Riera M, et al. Visceral leishmaniasis: another HIV-associated opportunistic infection? Report of eight cases and review of the literature. AIDS. 1991;5(2):201-7.
Altés, J., Salas, A., Riera, M., Udina, M., Galmés, A., Balanzat, J., Ballesteros, A., Buades, J., Salvá, F., & Villalonga, C. (1991). Visceral leishmaniasis: another HIV-associated opportunistic infection? Report of eight cases and review of the literature. AIDS (London, England), 5(2), 201-7.
Altés J, et al. Visceral Leishmaniasis: Another HIV-associated Opportunistic Infection? Report of Eight Cases and Review of the Literature. AIDS. 1991;5(2):201-7. PubMed PMID: 2031693.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Visceral leishmaniasis: another HIV-associated opportunistic infection? Report of eight cases and review of the literature. AU - Altés,J, AU - Salas,A, AU - Riera,M, AU - Udina,M, AU - Galmés,A, AU - Balanzat,J, AU - Ballesteros,A, AU - Buades,J, AU - Salvá,F, AU - Villalonga,C, PY - 1991/2/1/pubmed PY - 1991/2/1/medline PY - 1991/2/1/entrez SP - 201 EP - 7 JF - AIDS (London, England) JO - AIDS VL - 5 IS - 2 N2 - Visceral leishmaniasis (VL) is considered an opportunistic infection in immunocompromised patients. We review the clinical, laboratory, and therapeutic data in 63 patients (eight new cases and 55 cases reported in the literature) with Mediterranean VL (kala azar) and HIV-1 infection to determine whether VL should be considered an opportunistic infection in HIV-infected adults. We conclude that: (1) in areas where both leishmaniasis and HIV-1 infection are endemic, VL may be more frequent among HIV-infected adults; (2) in HIV-infected patients, the clinical picture did not differ significantly from classical kala azar, although it often ran a recurrent course, with resistance to antimonial therapy. We propose the inclusion of VL in the IVC-2 subgroup of the Centers for Disease Control (CDC) clinical classification of HIV-1 infection while prospective and larger studies further define whether there are clinical presentations that could justify adding VL to the list of opportunistic infections indicative of AIDS. SN - 0269-9370 UR - https://www.unboundmedicine.com/medline/citation/2031693/Visceral_leishmaniasis:_another_HIV_associated_opportunistic_infection_Report_of_eight_cases_and_review_of_the_literature_ DB - PRIME DP - Unbound Medicine ER -