Tags

Type your tag names separated by a space and hit enter

Essential oil from the underground parts of Laserpitium zernyi: potential source of alpha-bisabolol and its antimicrobial activity.
Nat Prod Commun. 2010 Feb; 5(2):307-10.NP

Abstract

The composition and antimicrobial activity of the essential oil from the underground parts (roots and rhizomes) of Laserpitium zernyi Hayek (Apiaceae) were investigated. The pale blue essential oil, obtained by hydrodistillation, was analyzed by GC and GC-MS. Forty-three compounds were identified (94.3% of total oil). The main constituent, beside alpha-pinene (31.6%) was alpha-bisabolol (30.9%), so this oil may be a novel potential natural source of this sesquiterpene alcohol. The antimicrobial activity was tested using the microdilution method against Gram (+) bacteria (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis), Gram (-) bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli), and two strains of yeast (Candida albicans). L. zernyi oil showed significant antibacterial activity against S. epidermidis, S. aureus and M. luteus, but lower activities against the other tested strains.

Authors+Show Affiliations

Institute of Pharmacognosy, Faculty of Pharmacy, University of Belgrade, V. Stepe 450, 11221 Belgrade, Serbia. visnjap@pharmacy.bg.ac.rsNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20334149

Citation

Popović, Visnja, et al. "Essential Oil From the Underground Parts of Laserpitium Zernyi: Potential Source of Alpha-bisabolol and Its Antimicrobial Activity." Natural Product Communications, vol. 5, no. 2, 2010, pp. 307-10.
Popović V, Petrović S, Pavlović M, et al. Essential oil from the underground parts of Laserpitium zernyi: potential source of alpha-bisabolol and its antimicrobial activity. Nat Prod Commun. 2010;5(2):307-10.
Popović, V., Petrović, S., Pavlović, M., Milenković, M., Couladis, M., Tzakou, O., Duraki, S., & Niketić, M. (2010). Essential oil from the underground parts of Laserpitium zernyi: potential source of alpha-bisabolol and its antimicrobial activity. Natural Product Communications, 5(2), 307-10.
Popović V, et al. Essential Oil From the Underground Parts of Laserpitium Zernyi: Potential Source of Alpha-bisabolol and Its Antimicrobial Activity. Nat Prod Commun. 2010;5(2):307-10. PubMed PMID: 20334149.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Essential oil from the underground parts of Laserpitium zernyi: potential source of alpha-bisabolol and its antimicrobial activity. AU - Popović,Visnja, AU - Petrović,Silvana, AU - Pavlović,Milica, AU - Milenković,Marina, AU - Couladis,Maria, AU - Tzakou,Olga, AU - Duraki,Semija, AU - Niketić,Marjan, PY - 2010/3/26/entrez PY - 2010/3/26/pubmed PY - 2010/5/5/medline SP - 307 EP - 10 JF - Natural product communications JO - Nat Prod Commun VL - 5 IS - 2 N2 - The composition and antimicrobial activity of the essential oil from the underground parts (roots and rhizomes) of Laserpitium zernyi Hayek (Apiaceae) were investigated. The pale blue essential oil, obtained by hydrodistillation, was analyzed by GC and GC-MS. Forty-three compounds were identified (94.3% of total oil). The main constituent, beside alpha-pinene (31.6%) was alpha-bisabolol (30.9%), so this oil may be a novel potential natural source of this sesquiterpene alcohol. The antimicrobial activity was tested using the microdilution method against Gram (+) bacteria (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Enterococcus faecalis), Gram (-) bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli), and two strains of yeast (Candida albicans). L. zernyi oil showed significant antibacterial activity against S. epidermidis, S. aureus and M. luteus, but lower activities against the other tested strains. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/20334149/Essential_oil_from_the_underground_parts_of_Laserpitium_zernyi:_potential_source_of_alpha_bisabolol_and_its_antimicrobial_activity_ L2 - https://medlineplus.gov/antibiotics.html DB - PRIME DP - Unbound Medicine ER -