Tags

Type your tag names separated by a space and hit enter

Relative glycaemic impact of customarily consumed portions of eighty-three foods measured by digesting in vitro and adjusting for food mass and apparent glucose disposal.
Br J Nutr. 2010 Aug; 104(3):407-17.BJ

Abstract

Practical values to guide food choices for control of postprandial glycaemia need to refer to entire foods in amounts customarily consumed. We tested an in vitro method for determining the relative glycaemic impact (RGI) of customarily consumed portions of foods. Sugars released during in vitro pancreatic digestion of eighty-three foods were measured as glucose equivalents (GE) per gram of food, adjusted by the glycaemic indexes of the sugars to obtain glycaemic GE (GGE) per gram and multiplied by food portion weight to obtain the GGE contribution of the food portion, its RGI. The results were compared with clinical GGE values from subjects who consumed the same food amounts. In vitro and in vivo GGE values were significantly correlated, but the slope of the regression equation was significantly less than one, meaning in vitro GGE values overestimated in vivo GGE values. Bland-Altman method comparison showed the in vitro-in vivo disparity to increase as mean GGE increased, suggesting the need to allow for different rates of homeostatic blood glucose disposal (GD) due to different GGE doses in the customarily consumed food portions. After GD correction, Bland-Altman method comparison showed that the bias in predicting in vivo GGE values from in vitro GGE values was almost completely removed (y = 0.071x - 0.89; R2 0.01). We conclude that in vitro food values for use in managing the glycaemic impact of customarily consumed food quantities require correction for blood GD that is dependent on the GGE content of the food portions involved.

Links

Publisher Full Text

Authors+Show Affiliations

Monro JA
New Zealand Institute for Plant and Food Research Limited, Palmerston North, New Zealand. monroj@crop.cri.nz
Wallace A
No affiliation info available
Mishra S
No affiliation info available
Eady S
No affiliation info available
Willis JA
No affiliation info available
Scott RS
No affiliation info available
Hedderley D
No affiliation info available

MeSH

AdultBlood GlucoseClinical Laboratory TechniquesDietary SucroseDigestionFoodGlycemic IndexHomeostasisHumansMaleMiddle AgedRegression AnalysisReproducibility of ResultsYoung Adult

Pub Type(s)

Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't
Validation Study

Language

eng

PubMed ID

20338071

Citation

Monro, John A., et al. "Relative Glycaemic Impact of Customarily Consumed Portions of Eighty-three Foods Measured By Digesting in Vitro and Adjusting for Food Mass and Apparent Glucose Disposal." The British Journal of Nutrition, vol. 104, no. 3, 2010, pp. 407-17.
Monro JA, Wallace A, Mishra S, et al. Relative glycaemic impact of customarily consumed portions of eighty-three foods measured by digesting in vitro and adjusting for food mass and apparent glucose disposal. Br J Nutr. 2010;104(3):407-17.
Monro, J. A., Wallace, A., Mishra, S., Eady, S., Willis, J. A., Scott, R. S., & Hedderley, D. (2010). Relative glycaemic impact of customarily consumed portions of eighty-three foods measured by digesting in vitro and adjusting for food mass and apparent glucose disposal. The British Journal of Nutrition, 104(3), 407-17. https://doi.org/10.1017/S0007114510000589
Monro JA, et al. Relative Glycaemic Impact of Customarily Consumed Portions of Eighty-three Foods Measured By Digesting in Vitro and Adjusting for Food Mass and Apparent Glucose Disposal. Br J Nutr. 2010;104(3):407-17. PubMed PMID: 20338071.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relative glycaemic impact of customarily consumed portions of eighty-three foods measured by digesting in vitro and adjusting for food mass and apparent glucose disposal. AU - Monro,John A, AU - Wallace,Alison, AU - Mishra,Suman, AU - Eady,Sarah, AU - Willis,Jinny A, AU - Scott,Russell S, AU - Hedderley,Duncan, Y1 - 2010/03/26/ PY - 2010/3/27/entrez PY - 2010/3/27/pubmed PY - 2010/8/13/medline SP - 407 EP - 17 JF - The British journal of nutrition JO - Br J Nutr VL - 104 IS - 3 N2 - Practical values to guide food choices for control of postprandial glycaemia need to refer to entire foods in amounts customarily consumed. We tested an in vitro method for determining the relative glycaemic impact (RGI) of customarily consumed portions of foods. Sugars released during in vitro pancreatic digestion of eighty-three foods were measured as glucose equivalents (GE) per gram of food, adjusted by the glycaemic indexes of the sugars to obtain glycaemic GE (GGE) per gram and multiplied by food portion weight to obtain the GGE contribution of the food portion, its RGI. The results were compared with clinical GGE values from subjects who consumed the same food amounts. In vitro and in vivo GGE values were significantly correlated, but the slope of the regression equation was significantly less than one, meaning in vitro GGE values overestimated in vivo GGE values. Bland-Altman method comparison showed the in vitro-in vivo disparity to increase as mean GGE increased, suggesting the need to allow for different rates of homeostatic blood glucose disposal (GD) due to different GGE doses in the customarily consumed food portions. After GD correction, Bland-Altman method comparison showed that the bias in predicting in vivo GGE values from in vitro GGE values was almost completely removed (y = 0.071x - 0.89; R2 0.01). We conclude that in vitro food values for use in managing the glycaemic impact of customarily consumed food quantities require correction for blood GD that is dependent on the GGE content of the food portions involved. SN - 1475-2662 UR - https://www.unboundmedicine.com/medline/citation/20338071/Relative_glycaemic_impact_of_customarily_consumed_portions_of_eighty_three_foods_measured_by_digesting_in_vitro_and_adjusting_for_food_mass_and_apparent_glucose_disposal_ L2 - https://www.cambridge.org/core/product/identifier/S0007114510000589/type/journal_article DB - PRIME DP - Unbound Medicine ER -