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[Mycotic keratitis in an eye care hospital in Mexico City].
Rev Iberoam Micol 2010; 27(2):57-61RI

Abstract

BACKGROUND

Some of the most common precipitating events for keratomycoses (fungal keratitis), include surgical trauma (after cornea transplantation), the use of contaminated contact lenses or alterations in lacrimal secretions. Diagnosis and treatment (to avoid loss of vision) for these type of infections are challenging.

OBJECTIVE

Retrospective review of the diagnosis, epidemiology, etiology and response to treatment in 219 patients with fungal keratitis in Mexico.

METHODS

We have studied the diagnosis, epidemiology, etiology and response to treatment in 219 patients from different states in the Mexican Republic in the Cornea Department at an Ophthalmology Hospital in Mexico D.F.

RESULTS

Trauma was the precipitating event in 77 patients (36%), of which 12 (5.4%) were due to surgical trauma; 152 patients (64.8%) did not report any prior trauma. There were 165 male (75.3%) and 54 female (24.6%) patients, with an average age of 46 years old. For clinical and visual treatment patients were treated with topical and oral antifungals and surgery. One or more surgeries were performed on a total of 81 patients (36.9%). A total of 62 patients (28.3%) received a corneal transplant, and 19 patients (8.7%) were subjected to conjunctival flap or scleral-conjunctival surgery.

CONCLUSIONS

In Mexico, keratomycoses affect mostly male patients in a 4:1 ratio over females. Fusarium solani was the most frequent agent of fungal keratitis in our study (37.2%), and the highest number of corneal ulcers and eviscerations (26%) was present in patients infected by Aspergillus. The best therapeutic responses were with combination of topical antifungals against dematiaceous fungi.

Authors+Show Affiliations

Laboratorio de Patología, Hospital Asociación Para Evitar la Ceguera en México Dr. Luis Sánchez Bulnes, Coyoacán, D. F., México. vivanzzini@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

spa

PubMed ID

20346302

Citation

Vanzzini Zago, Virginia, et al. "[Mycotic Keratitis in an Eye Care Hospital in Mexico City]." Revista Iberoamericana De Micologia, vol. 27, no. 2, 2010, pp. 57-61.
Vanzzini Zago V, Manzano-Gayosso P, Hernández-Hernández F, et al. [Mycotic keratitis in an eye care hospital in Mexico City]. Rev Iberoam Micol. 2010;27(2):57-61.
Vanzzini Zago, V., Manzano-Gayosso, P., Hernández-Hernández, F., Méndez-Tovar, L. J., Gómez-Leal, A., & López Martínez, R. (2010). [Mycotic keratitis in an eye care hospital in Mexico City]. Revista Iberoamericana De Micologia, 27(2), pp. 57-61. doi:10.1016/j.riam.2009.09.003.
Vanzzini Zago V, et al. [Mycotic Keratitis in an Eye Care Hospital in Mexico City]. Rev Iberoam Micol. 2010 Jun 30;27(2):57-61. PubMed PMID: 20346302.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Mycotic keratitis in an eye care hospital in Mexico City]. AU - Vanzzini Zago,Virginia, AU - Manzano-Gayosso,Patricia, AU - Hernández-Hernández,Francisca, AU - Méndez-Tovar,Luis Javier, AU - Gómez-Leal,Alfredo, AU - López Martínez,Rubén, Y1 - 2010/03/24/ PY - 2009/05/08/received PY - 2009/09/28/accepted PY - 2010/3/30/entrez PY - 2010/3/30/pubmed PY - 2010/12/18/medline SP - 57 EP - 61 JF - Revista iberoamericana de micologia JO - Rev Iberoam Micol VL - 27 IS - 2 N2 - BACKGROUND: Some of the most common precipitating events for keratomycoses (fungal keratitis), include surgical trauma (after cornea transplantation), the use of contaminated contact lenses or alterations in lacrimal secretions. Diagnosis and treatment (to avoid loss of vision) for these type of infections are challenging. OBJECTIVE: Retrospective review of the diagnosis, epidemiology, etiology and response to treatment in 219 patients with fungal keratitis in Mexico. METHODS: We have studied the diagnosis, epidemiology, etiology and response to treatment in 219 patients from different states in the Mexican Republic in the Cornea Department at an Ophthalmology Hospital in Mexico D.F. RESULTS: Trauma was the precipitating event in 77 patients (36%), of which 12 (5.4%) were due to surgical trauma; 152 patients (64.8%) did not report any prior trauma. There were 165 male (75.3%) and 54 female (24.6%) patients, with an average age of 46 years old. For clinical and visual treatment patients were treated with topical and oral antifungals and surgery. One or more surgeries were performed on a total of 81 patients (36.9%). A total of 62 patients (28.3%) received a corneal transplant, and 19 patients (8.7%) were subjected to conjunctival flap or scleral-conjunctival surgery. CONCLUSIONS: In Mexico, keratomycoses affect mostly male patients in a 4:1 ratio over females. Fusarium solani was the most frequent agent of fungal keratitis in our study (37.2%), and the highest number of corneal ulcers and eviscerations (26%) was present in patients infected by Aspergillus. The best therapeutic responses were with combination of topical antifungals against dematiaceous fungi. SN - 1130-1406 UR - https://www.unboundmedicine.com/medline/citation/20346302/[Mycotic_keratitis_in_an_eye_care_hospital_in_Mexico_City]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1130-1406(10)00017-3 DB - PRIME DP - Unbound Medicine ER -