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Metabolic evaluation in stone disease metabolic differences between the pediatric and adult patients with stone disease.
Urology 2010; 76(1):238-41U

Abstract

OBJECTIVE

To determine the metabolic risk factors in children and adults with stone disease and any differences between the metabolic risk factors of children and adult patients with stone disease.

METHODS

Between 1999 and 2007, 285 adults with recurrent stone disease and 71 children with primary or recurrent urinary stone disease underwent metabolic evaluation in our clinic. The evaluation included blood chemistry studies and 24-hour urine collection in the pediatric and adult groups.

RESULTS

The mean age of the children was 9.35 years (range: 1-14) and 42.1 years (range: 14-71) in the adult patients. Metabolic risk factors were demonstrated in 90.53% (n = 258) of the adult and 88.73% (n = 63) of the pediatric patients. Although hypercalciuria (50.5%, n = 144) was the most common metabolic risk factor in the adult group, hypocitraturia was the most common metabolic risk factor in the pediatric group (57.74%, n = 41). Furthermore, in the adult group, 136 patients had more than 1 risk factor, and in the pediatric group, 24 patients had more than 1 risk factor.

CONCLUSION

Although hypocitraturia is the most common risk factor in pediatric urolithiasis patients and hypercalciuria is the most common risk factor in adult patients, all patients with stone formation should be given a limited metabolic evaluation because such patients may also have a metabolic abnormality.

Authors+Show Affiliations

Ministry of Health, Ankara Dişkapi Yildirim Beyazit Education and Research Hospital, Department of Urology, Ankara, Turkey. osmanraifkarabacak@mynet.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

20350756

Citation

Karabacak, Osman Raif, et al. "Metabolic Evaluation in Stone Disease Metabolic Differences Between the Pediatric and Adult Patients With Stone Disease." Urology, vol. 76, no. 1, 2010, pp. 238-41.
Karabacak OR, Ipek B, Ozturk U, et al. Metabolic evaluation in stone disease metabolic differences between the pediatric and adult patients with stone disease. Urology. 2010;76(1):238-41.
Karabacak, O. R., Ipek, B., Ozturk, U., Demirel, F., Saltas, H., & Altug, U. (2010). Metabolic evaluation in stone disease metabolic differences between the pediatric and adult patients with stone disease. Urology, 76(1), pp. 238-41. doi:10.1016/j.urology.2010.01.036.
Karabacak OR, et al. Metabolic Evaluation in Stone Disease Metabolic Differences Between the Pediatric and Adult Patients With Stone Disease. Urology. 2010;76(1):238-41. PubMed PMID: 20350756.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Metabolic evaluation in stone disease metabolic differences between the pediatric and adult patients with stone disease. AU - Karabacak,Osman Raif, AU - Ipek,Bulent, AU - Ozturk,Ufuk, AU - Demirel,Fuat, AU - Saltas,Hakan, AU - Altug,Ugur, Y1 - 2010/03/28/ PY - 2009/09/09/received PY - 2009/12/16/revised PY - 2010/01/16/accepted PY - 2010/3/31/entrez PY - 2010/3/31/pubmed PY - 2010/8/17/medline SP - 238 EP - 41 JF - Urology JO - Urology VL - 76 IS - 1 N2 - OBJECTIVE: To determine the metabolic risk factors in children and adults with stone disease and any differences between the metabolic risk factors of children and adult patients with stone disease. METHODS: Between 1999 and 2007, 285 adults with recurrent stone disease and 71 children with primary or recurrent urinary stone disease underwent metabolic evaluation in our clinic. The evaluation included blood chemistry studies and 24-hour urine collection in the pediatric and adult groups. RESULTS: The mean age of the children was 9.35 years (range: 1-14) and 42.1 years (range: 14-71) in the adult patients. Metabolic risk factors were demonstrated in 90.53% (n = 258) of the adult and 88.73% (n = 63) of the pediatric patients. Although hypercalciuria (50.5%, n = 144) was the most common metabolic risk factor in the adult group, hypocitraturia was the most common metabolic risk factor in the pediatric group (57.74%, n = 41). Furthermore, in the adult group, 136 patients had more than 1 risk factor, and in the pediatric group, 24 patients had more than 1 risk factor. CONCLUSION: Although hypocitraturia is the most common risk factor in pediatric urolithiasis patients and hypercalciuria is the most common risk factor in adult patients, all patients with stone formation should be given a limited metabolic evaluation because such patients may also have a metabolic abnormality. SN - 1527-9995 UR - https://www.unboundmedicine.com/medline/citation/20350756/Metabolic_evaluation_in_stone_disease_metabolic_differences_between_the_pediatric_and_adult_patients_with_stone_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0090-4295(10)00115-9 DB - PRIME DP - Unbound Medicine ER -