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Hepatitis E virus infection: a general review with a focus on hemodialysis and kidney transplant patients.
Am J Nephrol. 2010; 31(5):398-407.AJ

Abstract

BACKGROUND

Hepatitis E virus (HEV) infection is a self-limited viral disease that causes acute hepatitis epidemics in developing countries. The common route of transmission for HEV is supposedly fecal-oral. Serological evidence may be unexpectedly found in hemodialysis (HD) patients and kidney transplant recipients. Although the route of HEV transmission is not usually determined in HD subjects, this virus seems to be transmitted either directly through HD or nosocomially. In this study, we gathered the published information on HEV infection in HD patients and kidney transplant recipients.

METHODS

For this review, we collected the relevant articles by searching through Medline and Google Scholar from January 1980 up to September 2009.

RESULTS

Some variables including older age, low education, living in rural versus urban areas and the duration of HD seem to be risk factors for HEV infection in HD patients. Compared with non-HD subjects, HEV infection may be specifically associated with poor outcome in HD patients. Specific considerations seem to be required to prevent transmission of HEV to HD patients.

CONCLUSION

More extensive investigations are required to determine the disease burden of HEV infection in HD subjects in countries which experience outbreaks of HEV infection.

Authors+Show Affiliations

Infectious Diseases and Tropical Medicine, Urology and Nephrology Research Center, Shahid Beheshti University, Tehran, Islamic Republic of Iran. h_sasan @ hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

20357431

Citation

Hosseini-Moghaddam, Seyed Mohammadmehdi, et al. "Hepatitis E Virus Infection: a General Review With a Focus On Hemodialysis and Kidney Transplant Patients." American Journal of Nephrology, vol. 31, no. 5, 2010, pp. 398-407.
Hosseini-Moghaddam SM, Zarei A, Alavian SM, et al. Hepatitis E virus infection: a general review with a focus on hemodialysis and kidney transplant patients. Am J Nephrol. 2010;31(5):398-407.
Hosseini-Moghaddam, S. M., Zarei, A., Alavian, S. M., & Mansouri, M. (2010). Hepatitis E virus infection: a general review with a focus on hemodialysis and kidney transplant patients. American Journal of Nephrology, 31(5), 398-407. https://doi.org/10.1159/000294505
Hosseini-Moghaddam SM, et al. Hepatitis E Virus Infection: a General Review With a Focus On Hemodialysis and Kidney Transplant Patients. Am J Nephrol. 2010;31(5):398-407. PubMed PMID: 20357431.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hepatitis E virus infection: a general review with a focus on hemodialysis and kidney transplant patients. AU - Hosseini-Moghaddam,Seyed Mohammadmehdi, AU - Zarei,Afagh, AU - Alavian,Seyed Moayed, AU - Mansouri,Mehdi, Y1 - 2010/03/31/ PY - 2009/09/13/received PY - 2010/03/01/accepted PY - 2010/4/2/entrez PY - 2010/4/2/pubmed PY - 2010/10/13/medline SP - 398 EP - 407 JF - American journal of nephrology JO - Am J Nephrol VL - 31 IS - 5 N2 - BACKGROUND: Hepatitis E virus (HEV) infection is a self-limited viral disease that causes acute hepatitis epidemics in developing countries. The common route of transmission for HEV is supposedly fecal-oral. Serological evidence may be unexpectedly found in hemodialysis (HD) patients and kidney transplant recipients. Although the route of HEV transmission is not usually determined in HD subjects, this virus seems to be transmitted either directly through HD or nosocomially. In this study, we gathered the published information on HEV infection in HD patients and kidney transplant recipients. METHODS: For this review, we collected the relevant articles by searching through Medline and Google Scholar from January 1980 up to September 2009. RESULTS: Some variables including older age, low education, living in rural versus urban areas and the duration of HD seem to be risk factors for HEV infection in HD patients. Compared with non-HD subjects, HEV infection may be specifically associated with poor outcome in HD patients. Specific considerations seem to be required to prevent transmission of HEV to HD patients. CONCLUSION: More extensive investigations are required to determine the disease burden of HEV infection in HD subjects in countries which experience outbreaks of HEV infection. SN - 1421-9670 UR - https://www.unboundmedicine.com/medline/citation/20357431/Hepatitis_E_virus_infection:_a_general_review_with_a_focus_on_hemodialysis_and_kidney_transplant_patients_ L2 - https://www.karger.com?DOI=10.1159/000294505 DB - PRIME DP - Unbound Medicine ER -