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[Prevalence of vitamin B-12 deficiency in older adults].
Rev Med Chil. 2010 Jan; 138(1):44-52.RM

Abstract

BACKGROUND

There is a correlation between aging and the decrease of plasma levels of vitamin B-12.

AIM

To determine the prevalence of vitamin B-12 and folate deficiency and its hematological impact among older adults (AM).

MATERIAL AND METHODS

Cross-sectional study, in 1028 subjects aged 65 to 87years, living in community and evaluated between 2005 and 2008. Percentile distribution of vitamin B-12, folate, hemoglobin, packed red cell volume and mean cell volume by gender and age were analyzed. Deficiency was defined as vitamin B-12 levels < 148 pmol/L, marginal deficiency as vitamin B-12 levels < 221 pmol/L, anemia was defined as a hemoglobin < 13 and 12 g/dL among men and women, respectively.

RESULTS

The prevalence of vitamin B-12 deficiency was 12% and the figure for marginal deficiency was 25.4%. Males were more affected than females (p < 0.001). The frequency of anemia was 8.6%o, and was higher among women (p = 0.004).

CONCLUSIONS

There is a high prevalence of full blown and marginal deficit of vitamin B-12 among the elderly. This deficiency should be considered for correction through public nutrition policies.

Authors+Show Affiliations

Unidad de Salud Pública y Nutrición, Instituto Nutrición y Tecnología en Alimentos, Universidad de Chile, Santiago, Chile. hsanchez@inta.clNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

spa

PubMed ID

20361150

Citation

Sánchez, Hugo, et al. "[Prevalence of Vitamin B-12 Deficiency in Older Adults]." Revista Medica De Chile, vol. 138, no. 1, 2010, pp. 44-52.
Sánchez H, Albala C, Herlramp F E, et al. [Prevalence of vitamin B-12 deficiency in older adults]. Rev Med Chil. 2010;138(1):44-52.
Sánchez, H., Albala, C., Herlramp F, E., Verdugo, R., Lavados, M., Castillo, J. L., Lera, L., & Uauy, R. (2010). [Prevalence of vitamin B-12 deficiency in older adults]. Revista Medica De Chile, 138(1), 44-52. https://doi.org//S0034-98872010000100006
Sánchez H, et al. [Prevalence of Vitamin B-12 Deficiency in Older Adults]. Rev Med Chil. 2010;138(1):44-52. PubMed PMID: 20361150.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Prevalence of vitamin B-12 deficiency in older adults]. AU - Sánchez,Hugo, AU - Albala,Cecilia, AU - Herlramp F,Eva, AU - Verdugo,Renato, AU - Lavados,Manuel, AU - Castillo,José Luis, AU - Lera,Lydia, AU - Uauy,Ricardo, Y1 - 2010/03/26/ PY - 2010/4/3/entrez PY - 2010/4/3/pubmed PY - 2010/11/16/medline SP - 44 EP - 52 JF - Revista medica de Chile JO - Rev Med Chil VL - 138 IS - 1 N2 - BACKGROUND: There is a correlation between aging and the decrease of plasma levels of vitamin B-12. AIM: To determine the prevalence of vitamin B-12 and folate deficiency and its hematological impact among older adults (AM). MATERIAL AND METHODS: Cross-sectional study, in 1028 subjects aged 65 to 87years, living in community and evaluated between 2005 and 2008. Percentile distribution of vitamin B-12, folate, hemoglobin, packed red cell volume and mean cell volume by gender and age were analyzed. Deficiency was defined as vitamin B-12 levels < 148 pmol/L, marginal deficiency as vitamin B-12 levels < 221 pmol/L, anemia was defined as a hemoglobin < 13 and 12 g/dL among men and women, respectively. RESULTS: The prevalence of vitamin B-12 deficiency was 12% and the figure for marginal deficiency was 25.4%. Males were more affected than females (p < 0.001). The frequency of anemia was 8.6%o, and was higher among women (p = 0.004). CONCLUSIONS: There is a high prevalence of full blown and marginal deficit of vitamin B-12 among the elderly. This deficiency should be considered for correction through public nutrition policies. SN - 0034-9887 UR - https://www.unboundmedicine.com/medline/citation/20361150/[Prevalence_of_vitamin_B_12_deficiency_in_older_adults]_ L2 - http://www.scielo.cl/scielo.php?script=sci_arttext&amp;pid=S0034-98872010000100006&amp;lng=en&amp;nrm=iso&amp;tlng=en DB - PRIME DP - Unbound Medicine ER -