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Formulation and evaluation of Cetirizine dihydrochloride orodispersible tablet.
Pak J Pharm Sci. 2010 Apr; 23(2):232-5.PJ

Abstract

Cetirizine orodispersible tablets were prepared to achieve quick onset of action and for maximum bioavailability. Tablets were prepared using cetirizine along with camphor and mannitol in the proportion of 1:1:1, 1:1:3, and 1:1:6. The flow property of granules was found to be good for the formulation CZ2 (1:1:3). The hardness and friability of all the formulations were found to be within the standard limit for orodispersible tablets. Disintegration time was found to be rapid in formulation CZ2 (1:1:3).The in vitro dissolution time was found to be 100% in 11 minutes for the formulation CZ2 (1:1:3).

Authors+Show Affiliations

Department of Pharmaceutics, PSG College of Pharmacy, Coimbatore - 641004. subbu3j@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20363705

Citation

Subramanian, S, et al. "Formulation and Evaluation of Cetirizine Dihydrochloride Orodispersible Tablet." Pakistan Journal of Pharmaceutical Sciences, vol. 23, no. 2, 2010, pp. 232-5.
Subramanian S, Sankar V, Manakadan AA, et al. Formulation and evaluation of Cetirizine dihydrochloride orodispersible tablet. Pak J Pharm Sci. 2010;23(2):232-5.
Subramanian, S., Sankar, V., Manakadan, A. A., Ismail, S., & Andhuvan, G. (2010). Formulation and evaluation of Cetirizine dihydrochloride orodispersible tablet. Pakistan Journal of Pharmaceutical Sciences, 23(2), 232-5.
Subramanian S, et al. Formulation and Evaluation of Cetirizine Dihydrochloride Orodispersible Tablet. Pak J Pharm Sci. 2010;23(2):232-5. PubMed PMID: 20363705.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Formulation and evaluation of Cetirizine dihydrochloride orodispersible tablet. AU - Subramanian,S, AU - Sankar,V, AU - Manakadan,Asha Asokan, AU - Ismail,Sareena, AU - Andhuvan,G, PY - 2010/4/6/entrez PY - 2010/4/7/pubmed PY - 2010/6/4/medline SP - 232 EP - 5 JF - Pakistan journal of pharmaceutical sciences JO - Pak J Pharm Sci VL - 23 IS - 2 N2 - Cetirizine orodispersible tablets were prepared to achieve quick onset of action and for maximum bioavailability. Tablets were prepared using cetirizine along with camphor and mannitol in the proportion of 1:1:1, 1:1:3, and 1:1:6. The flow property of granules was found to be good for the formulation CZ2 (1:1:3). The hardness and friability of all the formulations were found to be within the standard limit for orodispersible tablets. Disintegration time was found to be rapid in formulation CZ2 (1:1:3).The in vitro dissolution time was found to be 100% in 11 minutes for the formulation CZ2 (1:1:3). SN - 1011-601X UR - https://www.unboundmedicine.com/medline/citation/20363705/Formulation_and_evaluation_of_Cetirizine_dihydrochloride_orodispersible_tablet_ DB - PRIME DP - Unbound Medicine ER -