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[Effect of soy isoflavones on peri-menopausal symptom and estrogen].
Wei Sheng Yan Jiu. 2010 Jan; 39(1):56-9.WS

Abstract

OBJECTIVE

To study the effect of soy isoflavones (SI) on improving peri-menopausal symptoms and the secretion of estrogen.

METHODS

Fifty women accompany with peri-menopausal symptoms were single-blindly randomized into two groups, the SI group with a daily 120 mg/d of soy isoflavones for eight weeks and the control group with placebos. Serum 17 beta-estrodiol (E2), follicle-stimulating hormone (FSH) and luteinizing hormone (LH), progesterone, testosterone and prolactin (PRL) were assessed at baseline and after 8 weeks of observation. The symptoms, such as the frequency of hot flash and sweating, insomnia and Kuppermann scores were observed.

RESULTS

By the end of the trial, BMI was significantly increased (P < 0.05). Hot flashes, Kuppermann scores and other index were significantly decreased (P < 0.01), and E2, progesterone and testosterone were significantly increased (P < 0.01 or P < 0.05). FSH was significantly decreased in SI group (P < 0.01). In comparison with control group, hot flash frequency, vaginal dryness, Kuppermann scores and other index were significantly decreased in SI group, E2, PRL and testosterone were also significantly increased in SI group and FSH, 2H were decreased.

CONCLUSION

Menopausal symptoms and the secretion of estrogen were improved in peri-menopausal women on a daily dosage of 120 mg of soy isoflavones.

Authors+Show Affiliations

Department of Nutrition, The first Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. clala_008@sina.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Randomized Controlled Trial

Language

chi

PubMed ID

20364590

Citation

Li, Yanling, et al. "[Effect of Soy Isoflavones On Peri-menopausal Symptom and Estrogen]." Wei Sheng Yan Jiu = Journal of Hygiene Research, vol. 39, no. 1, 2010, pp. 56-9.
Li Y, Liu K, Lei W, et al. [Effect of soy isoflavones on peri-menopausal symptom and estrogen]. Wei Sheng Yan Jiu. 2010;39(1):56-9.
Li, Y., Liu, K., Lei, W., & Zhang, K. (2010). [Effect of soy isoflavones on peri-menopausal symptom and estrogen]. Wei Sheng Yan Jiu = Journal of Hygiene Research, 39(1), 56-9.
Li Y, et al. [Effect of Soy Isoflavones On Peri-menopausal Symptom and Estrogen]. Wei Sheng Yan Jiu. 2010;39(1):56-9. PubMed PMID: 20364590.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Effect of soy isoflavones on peri-menopausal symptom and estrogen]. AU - Li,Yanling, AU - Liu,Kemin, AU - Lei,Wen, AU - Zhang,Keming, PY - 2010/4/7/entrez PY - 2010/4/7/pubmed PY - 2012/7/7/medline SP - 56 EP - 9 JF - Wei sheng yan jiu = Journal of hygiene research JO - Wei Sheng Yan Jiu VL - 39 IS - 1 N2 - OBJECTIVE: To study the effect of soy isoflavones (SI) on improving peri-menopausal symptoms and the secretion of estrogen. METHODS: Fifty women accompany with peri-menopausal symptoms were single-blindly randomized into two groups, the SI group with a daily 120 mg/d of soy isoflavones for eight weeks and the control group with placebos. Serum 17 beta-estrodiol (E2), follicle-stimulating hormone (FSH) and luteinizing hormone (LH), progesterone, testosterone and prolactin (PRL) were assessed at baseline and after 8 weeks of observation. The symptoms, such as the frequency of hot flash and sweating, insomnia and Kuppermann scores were observed. RESULTS: By the end of the trial, BMI was significantly increased (P < 0.05). Hot flashes, Kuppermann scores and other index were significantly decreased (P < 0.01), and E2, progesterone and testosterone were significantly increased (P < 0.01 or P < 0.05). FSH was significantly decreased in SI group (P < 0.01). In comparison with control group, hot flash frequency, vaginal dryness, Kuppermann scores and other index were significantly decreased in SI group, E2, PRL and testosterone were also significantly increased in SI group and FSH, 2H were decreased. CONCLUSION: Menopausal symptoms and the secretion of estrogen were improved in peri-menopausal women on a daily dosage of 120 mg of soy isoflavones. SN - 1000-8020 UR - https://www.unboundmedicine.com/medline/citation/20364590/[Effect_of_soy_isoflavones_on_peri_menopausal_symptom_and_estrogen]_ L2 - https://medlineplus.gov/menopause.html DB - PRIME DP - Unbound Medicine ER -