[Review on the neuroprotective effects of green tea polyphenols for the treatment of neurodegenerative diseases].Wei Sheng Yan Jiu. 2010 Jan; 39(1):123-6.WS
Considering the multi-etiological characters of neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease, the current pharmacological approaches using drugs oriented towards a single molecular target possess limited ability to modify the course of the diseases. Green tea polyphenols have been reported to possess more than two active neuroprotective-neurorescue moieties that simultaneously manipulate multiple targets involved in neurodegeneration. This review aims to shed light on the multipharmacological neuroprotective activities and the mechanisms of green tea polyphenols on neurodegenerative diseases.