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Burst transcranial magnetic stimulation: which tinnitus characteristics influence the amount of transient tinnitus suppression?
Eur J Neurol. 2010 Sep; 17(9):1141-7.EJ

Abstract

BACKGROUND

Transcranial Magnetic Stimulation (TMS) is a method capable of temporarily suppressing tinnitus by delivering tonic or burst stimuli. Burst TMS has a high interindividual variability and low effect size. Tinnitus type and laterality, tinnitus-related distress, and tinnitus duration might contribute to this large individual variation.

METHODS

The effect of burst TMS on the auditory cortex in 100 male individuals is evaluated with coil placed over the auditory cortex. For unilateral tinnitus, this coil was placed contralaterally to the tinnitus, whilst for bilateral tinnitus the coil was placed over the right auditory cortex. The site of maximal tinnitus suppression is determined using 1-Hz stimulation with five pulses per burst (intensity of the stimulation set at 90% of the motor threshold). When tinnitus suppression is noted, the patients are asked to estimate the decrease in tinnitus in percentage using the numeric rating scale. The procedure is repeated with stimulations at 5, 10 and 20 Hz, each stimulation session consisting of 200 pulses.

RESULTS

Results demonstrate that burst stimulation can decrease the perceived tinnitus intensity transiently in 57.83% of the patients. Patients with bilateral tinnitus respond better to burst TMS than patients with unilateral tinnitus and highly distressed patients presenting with unilateral pure tone tinnitus fail to bust TMS.

CONCLUSIONS

Burst TMS modulates both unilateral and bilateral tinnitus, both high and low distress and both pure tones and narrow band tinnitus. However, the suppression effect is moderated by tinnitus type and laterality, tinnitus-related distress, and tinnitus duration.

Authors+Show Affiliations

Brain, & TRI, University Hospital Antwerp, Antwerp, Belgium. sven.vanneste@ua.ac.beNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

20374277

Citation

Vanneste, S, et al. "Burst Transcranial Magnetic Stimulation: Which Tinnitus Characteristics Influence the Amount of Transient Tinnitus Suppression?" European Journal of Neurology, vol. 17, no. 9, 2010, pp. 1141-7.
Vanneste S, Plazier M, van der Loo E, et al. Burst transcranial magnetic stimulation: which tinnitus characteristics influence the amount of transient tinnitus suppression? Eur J Neurol. 2010;17(9):1141-7.
Vanneste, S., Plazier, M., van der Loo, E., Ost, J., Van de Heyning, P., & De Ridder, D. (2010). Burst transcranial magnetic stimulation: which tinnitus characteristics influence the amount of transient tinnitus suppression? European Journal of Neurology, 17(9), 1141-7. https://doi.org/10.1111/j.1468-1331.2010.02987.x
Vanneste S, et al. Burst Transcranial Magnetic Stimulation: Which Tinnitus Characteristics Influence the Amount of Transient Tinnitus Suppression. Eur J Neurol. 2010;17(9):1141-7. PubMed PMID: 20374277.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Burst transcranial magnetic stimulation: which tinnitus characteristics influence the amount of transient tinnitus suppression? AU - Vanneste,S, AU - Plazier,M, AU - van der Loo,E, AU - Ost,J, AU - Van de Heyning,P, AU - De Ridder,D, Y1 - 2010/03/30/ PY - 2010/4/9/entrez PY - 2010/4/9/pubmed PY - 2011/4/27/medline SP - 1141 EP - 7 JF - European journal of neurology JO - Eur J Neurol VL - 17 IS - 9 N2 - BACKGROUND: Transcranial Magnetic Stimulation (TMS) is a method capable of temporarily suppressing tinnitus by delivering tonic or burst stimuli. Burst TMS has a high interindividual variability and low effect size. Tinnitus type and laterality, tinnitus-related distress, and tinnitus duration might contribute to this large individual variation. METHODS: The effect of burst TMS on the auditory cortex in 100 male individuals is evaluated with coil placed over the auditory cortex. For unilateral tinnitus, this coil was placed contralaterally to the tinnitus, whilst for bilateral tinnitus the coil was placed over the right auditory cortex. The site of maximal tinnitus suppression is determined using 1-Hz stimulation with five pulses per burst (intensity of the stimulation set at 90% of the motor threshold). When tinnitus suppression is noted, the patients are asked to estimate the decrease in tinnitus in percentage using the numeric rating scale. The procedure is repeated with stimulations at 5, 10 and 20 Hz, each stimulation session consisting of 200 pulses. RESULTS: Results demonstrate that burst stimulation can decrease the perceived tinnitus intensity transiently in 57.83% of the patients. Patients with bilateral tinnitus respond better to burst TMS than patients with unilateral tinnitus and highly distressed patients presenting with unilateral pure tone tinnitus fail to bust TMS. CONCLUSIONS: Burst TMS modulates both unilateral and bilateral tinnitus, both high and low distress and both pure tones and narrow band tinnitus. However, the suppression effect is moderated by tinnitus type and laterality, tinnitus-related distress, and tinnitus duration. SN - 1468-1331 UR - https://www.unboundmedicine.com/medline/citation/20374277/Burst_transcranial_magnetic_stimulation:_which_tinnitus_characteristics_influence_the_amount_of_transient_tinnitus_suppression L2 - https://doi.org/10.1111/j.1468-1331.2010.02987.x DB - PRIME DP - Unbound Medicine ER -