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Squaramide-catalyzed enantioselective Friedel-Crafts reaction of indoles with imines.
Chem Commun (Camb). 2010 May 07; 46(17):3004-6.CC

Abstract

Chiral squaramides are highly enantioselective catalysts for Friedel-Crafts reaction of indoles with N-tosyl imines, affording 3-indolyl methanamine products in 85-96% yields and 84-96% ees.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Qian Y
State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Ma G
No affiliation info available
Lv A
No affiliation info available
Zhu HL
No affiliation info available
Zhao J
No affiliation info available
Rawal VH
No affiliation info available

MeSH

AmidesCatalysisIminesIndolesStereoisomerism

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20386849

Citation

Qian, Yong, et al. "Squaramide-catalyzed Enantioselective Friedel-Crafts Reaction of Indoles With Imines." Chemical Communications (Cambridge, England), vol. 46, no. 17, 2010, pp. 3004-6.
Qian Y, Ma G, Lv A, et al. Squaramide-catalyzed enantioselective Friedel-Crafts reaction of indoles with imines. Chem Commun (Camb). 2010;46(17):3004-6.
Qian, Y., Ma, G., Lv, A., Zhu, H. L., Zhao, J., & Rawal, V. H. (2010). Squaramide-catalyzed enantioselective Friedel-Crafts reaction of indoles with imines. Chemical Communications (Cambridge, England), 46(17), 3004-6. https://doi.org/10.1039/b922120d
Qian Y, et al. Squaramide-catalyzed Enantioselective Friedel-Crafts Reaction of Indoles With Imines. Chem Commun (Camb). 2010 May 7;46(17):3004-6. PubMed PMID: 20386849.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Squaramide-catalyzed enantioselective Friedel-Crafts reaction of indoles with imines. AU - Qian,Yong, AU - Ma,Gaoyuan, AU - Lv,Aifeng, AU - Zhu,Hai-Liang, AU - Zhao,Jing, AU - Rawal,Viresh H, Y1 - 2010/03/23/ PY - 2010/4/14/entrez PY - 2010/4/14/pubmed PY - 2010/6/29/medline SP - 3004 EP - 6 JF - Chemical communications (Cambridge, England) JO - Chem Commun (Camb) VL - 46 IS - 17 N2 - Chiral squaramides are highly enantioselective catalysts for Friedel-Crafts reaction of indoles with N-tosyl imines, affording 3-indolyl methanamine products in 85-96% yields and 84-96% ees. SN - 1364-548X UR - https://www.unboundmedicine.com/medline/citation/20386849/Squaramide_catalyzed_enantioselective_Friedel_Crafts_reaction_of_indoles_with_imines_ DB - PRIME DP - Unbound Medicine ER -
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