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Extraction, separation and isolation of volatiles from Vitex agnus-castus L. (Verbenaceae) wild species of Sardinia, Italy, by supercritical CO2.
Nat Prod Res. 2010 Apr; 24(6):569-79.NP

Abstract

Isolation of volatile concentrates from leaves, flowers and fruits of Vitex agnus-castus L. have been obtained by supercritical extraction with carbon dioxide. The composition of the volatile concentrates has been analysed by GC/MS. In all plant organs, the extracts are composed chiefly of alpha-pinene, sabinene, 1,8-cineole, alpha-terpinyl acetate, (E)-caryophyllene, (E)-beta-farnesene, bicyclogermacrene, spathulenol and manool. The main difference observed was in the content of sclarene, which was not present in the samples from flowers or fruits. To complete the investigation, a comparison with the hydrodistilled oil has been carried out. The minimal inhibitory concentration (MIC) and the minimal lethal concentration were used to evaluate the antifungal activity of the oils against dermatophyte strains (Trichophyton mentagrophytes, Microsporum canis, T. rubrum, M. gypseum and Epidermophyton floccosum). Antifungal activity of the leaf essential oil was the highest, with MIC values of 0.64 microL mL(-1) for most of the strains.

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Authors+Show Affiliations

Marongiu B
Dipartimento di Scienze Chimiche, Universita degli Studi di Cagliari, Cittadella Universitaria di Monserrato, 09042 Monserrato, Italy.
Piras A
No affiliation info available
Porcedda S
No affiliation info available
Falconieri D
No affiliation info available
Goncalves MJ
No affiliation info available
Salgueiro L
No affiliation info available
Maxia A
No affiliation info available
Lai R
No affiliation info available

MeSH

Antifungal AgentsArthrodermataceaeFlowersFruitItalyMicrobial Sensitivity TestsOils, VolatilePlant LeavesVitex

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20397107

Citation

Marongiu, Bruno, et al. "Extraction, Separation and Isolation of Volatiles From Vitex Agnus-castus L. (Verbenaceae) Wild Species of Sardinia, Italy, By Supercritical CO2." Natural Product Research, vol. 24, no. 6, 2010, pp. 569-79.
Marongiu B, Piras A, Porcedda S, et al. Extraction, separation and isolation of volatiles from Vitex agnus-castus L. (Verbenaceae) wild species of Sardinia, Italy, by supercritical CO2. Nat Prod Res. 2010;24(6):569-79.
Marongiu, B., Piras, A., Porcedda, S., Falconieri, D., Goncalves, M. J., Salgueiro, L., Maxia, A., & Lai, R. (2010). Extraction, separation and isolation of volatiles from Vitex agnus-castus L. (Verbenaceae) wild species of Sardinia, Italy, by supercritical CO2. Natural Product Research, 24(6), 569-79. https://doi.org/10.1080/14786410902899915
Marongiu B, et al. Extraction, Separation and Isolation of Volatiles From Vitex Agnus-castus L. (Verbenaceae) Wild Species of Sardinia, Italy, By Supercritical CO2. Nat Prod Res. 2010;24(6):569-79. PubMed PMID: 20397107.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Extraction, separation and isolation of volatiles from Vitex agnus-castus L. (Verbenaceae) wild species of Sardinia, Italy, by supercritical CO2. AU - Marongiu,Bruno, AU - Piras,Alessandra, AU - Porcedda,Silvia, AU - Falconieri,Danilo, AU - Goncalves,Maria J, AU - Salgueiro,Ligia, AU - Maxia,Andrea, AU - Lai,Roberta, PY - 2010/4/17/entrez PY - 2010/4/17/pubmed PY - 2010/7/28/medline SP - 569 EP - 79 JF - Natural product research JO - Nat Prod Res VL - 24 IS - 6 N2 - Isolation of volatile concentrates from leaves, flowers and fruits of Vitex agnus-castus L. have been obtained by supercritical extraction with carbon dioxide. The composition of the volatile concentrates has been analysed by GC/MS. In all plant organs, the extracts are composed chiefly of alpha-pinene, sabinene, 1,8-cineole, alpha-terpinyl acetate, (E)-caryophyllene, (E)-beta-farnesene, bicyclogermacrene, spathulenol and manool. The main difference observed was in the content of sclarene, which was not present in the samples from flowers or fruits. To complete the investigation, a comparison with the hydrodistilled oil has been carried out. The minimal inhibitory concentration (MIC) and the minimal lethal concentration were used to evaluate the antifungal activity of the oils against dermatophyte strains (Trichophyton mentagrophytes, Microsporum canis, T. rubrum, M. gypseum and Epidermophyton floccosum). Antifungal activity of the leaf essential oil was the highest, with MIC values of 0.64 microL mL(-1) for most of the strains. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/20397107/Extraction_separation_and_isolation_of_volatiles_from_Vitex_agnus_castus_L___Verbenaceae__wild_species_of_Sardinia_Italy_by_supercritical_CO2_ L2 - https://www.tandfonline.com/doi/full/10.1080/14786410902899915 DB - PRIME DP - Unbound Medicine ER -