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[Value of estimated glomerular filtration rate and serum creatinine for predicting long-term survival in Chinese patients after isolated coronary artery bypass graft surgery].
Zhonghua Xin Xue Guan Bing Za Zhi. 2010 Feb; 38(2):99-102.ZX

Abstract

OBJECTIVE

To compare the predictive value of glomerular filtration rate (GFR) estimated by the Cockcroft-Gault formula or the modification of diet in renal disease (MDRD) equation and serum creatinine for in-hospital and long-term mortality post coronary artery bypass graft surgery (CABG).

METHODS

Clinical data of 5559 consecutive patients undergoing isolated CABG were retrospectively analyzed. The main outcomes were in-hospital mortality and long-term mortality. Estimated GFR was calculated by the Cockcroft-Gault formula and MDRD equation respectively. Receiver-operating characteristic curves and Cox's analysis were used for the comparison.

RESULTS

Follow-up was complete in 5485 patients (97.6%). Analysis of receiver-operating characteristic curves showed that GFR estimated by the Cockcroft-Gault formula had a maximal accuracy for predicting in-hospital mortality (area under the curve: 0.755, P < 0.01). Multivariate logistic analysis and the Cox's analysis results indicated estimated GFR < 60 mlxmin(-1)x1.73 m(-2) base on the Cockcroft-Gault formula was an independent risk factor for in-hospital and long-term mortality (hazard ratio 4.51 for in-hospital mortality, P < 0.01; hazard ratio 1.54 for long-term mortality, P < 0.01), both Cockcroft-Gault formula and MDRD equation were superior to serum creatinine for predicting in-hospital and long-term mortality post CABG.

CONCLUSION

GFR estimated by the Cockcroft-Gault formula was superior to GFR estimated by the MDRD equation for predicting in-hospital mortality, and estimated GFR was superior to serum creatinine for predicting in-hospital and long-term mortality.

Authors+Show Affiliations

Department of Cardiac Surgery, Cardiovascular Institute and Fu Wai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

20398551

Citation

Lin, Ye, et al. "[Value of Estimated Glomerular Filtration Rate and Serum Creatinine for Predicting Long-term Survival in Chinese Patients After Isolated Coronary Artery Bypass Graft Surgery]." Zhonghua Xin Xue Guan Bing Za Zhi, vol. 38, no. 2, 2010, pp. 99-102.
Lin Y, Zheng Z, Hu SS, et al. [Value of estimated glomerular filtration rate and serum creatinine for predicting long-term survival in Chinese patients after isolated coronary artery bypass graft surgery]. Zhonghua Xin Xue Guan Bing Za Zhi. 2010;38(2):99-102.
Lin, Y., Zheng, Z., Hu, S. S., Xu, J. P., Lü, F., Wang, W., Song, Y. H., Sun, H. S., Yuan, X., & Pan, X. B. (2010). [Value of estimated glomerular filtration rate and serum creatinine for predicting long-term survival in Chinese patients after isolated coronary artery bypass graft surgery]. Zhonghua Xin Xue Guan Bing Za Zhi, 38(2), 99-102.
Lin Y, et al. [Value of Estimated Glomerular Filtration Rate and Serum Creatinine for Predicting Long-term Survival in Chinese Patients After Isolated Coronary Artery Bypass Graft Surgery]. Zhonghua Xin Xue Guan Bing Za Zhi. 2010;38(2):99-102. PubMed PMID: 20398551.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Value of estimated glomerular filtration rate and serum creatinine for predicting long-term survival in Chinese patients after isolated coronary artery bypass graft surgery]. AU - Lin,Ye, AU - Zheng,Zhe, AU - Hu,Sheng-Shou, AU - Xu,Jian-Ping, AU - Lü,Feng, AU - Wang,Wei, AU - Song,Yun-Hu, AU - Sun,Han-Song, AU - Yuan,Xin, AU - Pan,Xiang-Bin, PY - 2010/4/20/entrez PY - 2010/4/20/pubmed PY - 2011/10/14/medline SP - 99 EP - 102 JF - Zhonghua xin xue guan bing za zhi JO - Zhonghua Xin Xue Guan Bing Za Zhi VL - 38 IS - 2 N2 - OBJECTIVE: To compare the predictive value of glomerular filtration rate (GFR) estimated by the Cockcroft-Gault formula or the modification of diet in renal disease (MDRD) equation and serum creatinine for in-hospital and long-term mortality post coronary artery bypass graft surgery (CABG). METHODS: Clinical data of 5559 consecutive patients undergoing isolated CABG were retrospectively analyzed. The main outcomes were in-hospital mortality and long-term mortality. Estimated GFR was calculated by the Cockcroft-Gault formula and MDRD equation respectively. Receiver-operating characteristic curves and Cox's analysis were used for the comparison. RESULTS: Follow-up was complete in 5485 patients (97.6%). Analysis of receiver-operating characteristic curves showed that GFR estimated by the Cockcroft-Gault formula had a maximal accuracy for predicting in-hospital mortality (area under the curve: 0.755, P < 0.01). Multivariate logistic analysis and the Cox's analysis results indicated estimated GFR < 60 mlxmin(-1)x1.73 m(-2) base on the Cockcroft-Gault formula was an independent risk factor for in-hospital and long-term mortality (hazard ratio 4.51 for in-hospital mortality, P < 0.01; hazard ratio 1.54 for long-term mortality, P < 0.01), both Cockcroft-Gault formula and MDRD equation were superior to serum creatinine for predicting in-hospital and long-term mortality post CABG. CONCLUSION: GFR estimated by the Cockcroft-Gault formula was superior to GFR estimated by the MDRD equation for predicting in-hospital mortality, and estimated GFR was superior to serum creatinine for predicting in-hospital and long-term mortality. SN - 0253-3758 UR - https://www.unboundmedicine.com/medline/citation/20398551/[Value_of_estimated_glomerular_filtration_rate_and_serum_creatinine_for_predicting_long_term_survival_in_Chinese_patients_after_isolated_coronary_artery_bypass_graft_surgery]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0253-3758&amp;year=2010&amp;vol=38&amp;issue=2&amp;fpage=99 DB - PRIME DP - Unbound Medicine ER -