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Copper-mediated cyclization-halogenation and cyclization-cyanation reactions of beta-hydroxyalkynes and o-alkynylphenols and anilines.
J Org Chem. 2010 May 21; 75(10):3412-9.JO

Abstract

The CuX (X = I, Br, Cl, CN)-mediated cyclization-halogenation and cyclization-cyanation reactions of beta-hydroxyalkynes and o-alkynylphenol and -aniline derivatives give rise to 3-halo- and 3-cyanofuro[3,2-b]pyrroles, 3-iodo-, 3-bromo-, and 3-cyanobenzofurans, and 3-cyanoindoles, respectively.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Swamy NK
School of Chemistry, University of Wollongong, Wollongong, New South Wales 2522, Australia.
Yazici A
No affiliation info available
Pyne SG
No affiliation info available

MeSH

AlkynesAniline CompoundsBenzofuransCopperCyclizationIndolesMolecular StructurePhenolsPyrrolesStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20408528

Citation

Swamy, Nalivela Kumara, et al. "Copper-mediated Cyclization-halogenation and Cyclization-cyanation Reactions of Beta-hydroxyalkynes and O-alkynylphenols and Anilines." The Journal of Organic Chemistry, vol. 75, no. 10, 2010, pp. 3412-9.
Swamy NK, Yazici A, Pyne SG. Copper-mediated cyclization-halogenation and cyclization-cyanation reactions of beta-hydroxyalkynes and o-alkynylphenols and anilines. J Org Chem. 2010;75(10):3412-9.
Swamy, N. K., Yazici, A., & Pyne, S. G. (2010). Copper-mediated cyclization-halogenation and cyclization-cyanation reactions of beta-hydroxyalkynes and o-alkynylphenols and anilines. The Journal of Organic Chemistry, 75(10), 3412-9. https://doi.org/10.1021/jo1005119
Swamy NK, Yazici A, Pyne SG. Copper-mediated Cyclization-halogenation and Cyclization-cyanation Reactions of Beta-hydroxyalkynes and O-alkynylphenols and Anilines. J Org Chem. 2010 May 21;75(10):3412-9. PubMed PMID: 20408528.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Copper-mediated cyclization-halogenation and cyclization-cyanation reactions of beta-hydroxyalkynes and o-alkynylphenols and anilines. AU - Swamy,Nalivela Kumara, AU - Yazici,Arife, AU - Pyne,Stephen G, PY - 2010/4/23/entrez PY - 2010/4/23/pubmed PY - 2010/9/2/medline SP - 3412 EP - 9 JF - The Journal of organic chemistry JO - J Org Chem VL - 75 IS - 10 N2 - The CuX (X = I, Br, Cl, CN)-mediated cyclization-halogenation and cyclization-cyanation reactions of beta-hydroxyalkynes and o-alkynylphenol and -aniline derivatives give rise to 3-halo- and 3-cyanofuro[3,2-b]pyrroles, 3-iodo-, 3-bromo-, and 3-cyanobenzofurans, and 3-cyanoindoles, respectively. SN - 1520-6904 UR - https://www.unboundmedicine.com/medline/citation/20408528/Copper_mediated_cyclization_halogenation_and_cyclization_cyanation_reactions_of_beta_hydroxyalkynes_and_o_alkynylphenols_and_anilines_ L2 - https://doi.org/10.1021/jo1005119 DB - PRIME DP - Unbound Medicine ER -