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Demonstration of angle widening using EyeCam after laser peripheral iridotomy in eyes with angle closure.
Am J Ophthalmol. 2010 Jun; 149(6):903-7.AJ

Abstract

PURPOSE

To evaluate EyeCam in detecting changes in angle configuration after laser peripheral iridotomy (LPI) in comparison to gonioscopy, the reference standard.

DESIGN

Prospective comparative study.

METHODS

Twenty-four subjects (24 eyes) with primary angle-closure glaucoma (PACG) were recruited. Gonioscopy and EyeCam (Clarity Medical Systems) imaging of all 4 angle quadrants were performed, before and 2 weeks after LPI. Images were graded according to angle structures visible by an observer masked to clinical data or the status of LPI, and were performed in a random order. Angle closure in a quadrant was defined as the inability to visualize the posterior trabecular meshwork. We determined the number of quadrants with closed angles and the mean number of clock hours of angle closure before and after LPI in comparison to gonioscopy.

RESULTS

Using EyeCam, all 24 eyes showed at least 1 quadrant of angle widening after LPI. The mean number of clock hours of angle closure decreased significantly, from 8.15 +/- 3.47 clock hours before LPI to 1.75 +/- 2.27 clock hours after LPI (P < .0001, Wilcoxon signed rank test). Overall, gonioscopy showed 1.0 +/- 1.41 (95% CI, 0.43-1.57) quadrants opening from closed to open after LPI compared to 2.0 +/- 1.28 (95% CI, 1.49-2.51, P = .009) quadrants with EyeCam. Intra-observer reproducibility of grading the extent of angle closure in clock hours in EyeCam images was moderate to good (intraclass correlation coefficient 0.831).

CONCLUSIONS

EyeCam may be used to document changes in angle configuration after LPI in eyes with PACG.

Authors+Show Affiliations

Singapore National Eye Centre & Singapore Eye Research Institute, Singapore.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20417499

Citation

Perera, Shamira A., et al. "Demonstration of Angle Widening Using EyeCam After Laser Peripheral Iridotomy in Eyes With Angle Closure." American Journal of Ophthalmology, vol. 149, no. 6, 2010, pp. 903-7.
Perera SA, Quek DT, Baskaran M, et al. Demonstration of angle widening using EyeCam after laser peripheral iridotomy in eyes with angle closure. Am J Ophthalmol. 2010;149(6):903-7.
Perera, S. A., Quek, D. T., Baskaran, M., Tun, T. A., Kumar, R. S., Friedman, D. S., & Aung, T. (2010). Demonstration of angle widening using EyeCam after laser peripheral iridotomy in eyes with angle closure. American Journal of Ophthalmology, 149(6), 903-7. https://doi.org/10.1016/j.ajo.2010.01.013
Perera SA, et al. Demonstration of Angle Widening Using EyeCam After Laser Peripheral Iridotomy in Eyes With Angle Closure. Am J Ophthalmol. 2010;149(6):903-7. PubMed PMID: 20417499.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Demonstration of angle widening using EyeCam after laser peripheral iridotomy in eyes with angle closure. AU - Perera,Shamira A, AU - Quek,Desmond T, AU - Baskaran,Mani, AU - Tun,Tin A, AU - Kumar,Rajesh S, AU - Friedman,David S, AU - Aung,Tin, Y1 - 2010/04/24/ PY - 2009/05/04/received PY - 2010/01/05/revised PY - 2010/01/05/accepted PY - 2010/4/27/entrez PY - 2010/4/27/pubmed PY - 2010/6/18/medline SP - 903 EP - 7 JF - American journal of ophthalmology JO - Am J Ophthalmol VL - 149 IS - 6 N2 - PURPOSE: To evaluate EyeCam in detecting changes in angle configuration after laser peripheral iridotomy (LPI) in comparison to gonioscopy, the reference standard. DESIGN: Prospective comparative study. METHODS: Twenty-four subjects (24 eyes) with primary angle-closure glaucoma (PACG) were recruited. Gonioscopy and EyeCam (Clarity Medical Systems) imaging of all 4 angle quadrants were performed, before and 2 weeks after LPI. Images were graded according to angle structures visible by an observer masked to clinical data or the status of LPI, and were performed in a random order. Angle closure in a quadrant was defined as the inability to visualize the posterior trabecular meshwork. We determined the number of quadrants with closed angles and the mean number of clock hours of angle closure before and after LPI in comparison to gonioscopy. RESULTS: Using EyeCam, all 24 eyes showed at least 1 quadrant of angle widening after LPI. The mean number of clock hours of angle closure decreased significantly, from 8.15 +/- 3.47 clock hours before LPI to 1.75 +/- 2.27 clock hours after LPI (P < .0001, Wilcoxon signed rank test). Overall, gonioscopy showed 1.0 +/- 1.41 (95% CI, 0.43-1.57) quadrants opening from closed to open after LPI compared to 2.0 +/- 1.28 (95% CI, 1.49-2.51, P = .009) quadrants with EyeCam. Intra-observer reproducibility of grading the extent of angle closure in clock hours in EyeCam images was moderate to good (intraclass correlation coefficient 0.831). CONCLUSIONS: EyeCam may be used to document changes in angle configuration after LPI in eyes with PACG. SN - 1879-1891 UR - https://www.unboundmedicine.com/medline/citation/20417499/Demonstration_of_angle_widening_using_EyeCam_after_laser_peripheral_iridotomy_in_eyes_with_angle_closure_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(10)00029-2 DB - PRIME DP - Unbound Medicine ER -