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Fetal cleft lip with and without cleft palate: comparison between MR imaging and US for prenatal diagnosis.
Eur J Radiol. 2011 Sep; 79(3):437-42.EJ

Abstract

OBJECTIVE

To describe the magnetic resonance (MR) imaging findings of fetal CL/CP and evaluate its diagnostic value.

METHODS AND MATERIALS

Twelve fetuses with CL/CP diagnosed by transabdominal US underwent MR imaging within 2 days of US. Half-Fourier acquisition single-shot turbo spin echo (HASTE) sequence on T2-weighted images was performed on sagittal, coronal, and axial planes anatomic to the fetuses during maternal breath holding. US and MR imaging findings were compared with final diagnoses obtained from post-natal physical examination or fetal autopsy.

RESULTS

Final diagnoses confirmed incomplete midline cleft lip (n=1), unilateral cleft lip and palate (n=7), bilateral cleft lip and palate (n=1), midline cleft lip and palate (n=3). US and MR imaging diagnosed all 12 fetuses with cleft lip and the laterality. 5 (45.5%) of 11 cleft palates were identified with US, 2 of 7 fetuses with unilateral cleft palate, 2 of 3 fetuses with midline cleft palate, and one fetus with bilateral cleft palate. On MR imaging, 10 (91%) of 11 cleft palates were correctly detected. One fetus with unilateral cleft palate was not detected. No false-positives occurred.

CONCLUSION

MR imaging is valuable for diagnosis of fetal CL/CP. It can demonstrate additional findings and provide more information compared with US.

Authors+Show Affiliations

Shandong Medical Imaging Research Institute, Jinan, 250021, China. wgb7932596@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

20418035

Citation

Wang, Guangbin, et al. "Fetal Cleft Lip With and Without Cleft Palate: Comparison Between MR Imaging and US for Prenatal Diagnosis." European Journal of Radiology, vol. 79, no. 3, 2011, pp. 437-42.
Wang G, Shan R, Zhao L, et al. Fetal cleft lip with and without cleft palate: comparison between MR imaging and US for prenatal diagnosis. Eur J Radiol. 2011;79(3):437-42.
Wang, G., Shan, R., Zhao, L., Zhu, X., & Zhang, X. (2011). Fetal cleft lip with and without cleft palate: comparison between MR imaging and US for prenatal diagnosis. European Journal of Radiology, 79(3), 437-42. https://doi.org/10.1016/j.ejrad.2010.03.026
Wang G, et al. Fetal Cleft Lip With and Without Cleft Palate: Comparison Between MR Imaging and US for Prenatal Diagnosis. Eur J Radiol. 2011;79(3):437-42. PubMed PMID: 20418035.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fetal cleft lip with and without cleft palate: comparison between MR imaging and US for prenatal diagnosis. AU - Wang,Guangbin, AU - Shan,Ruiqin, AU - Zhao,Lianxin, AU - Zhu,Xiangyu, AU - Zhang,Xinjuan, Y1 - 2010/04/24/ PY - 2010/02/08/received PY - 2010/03/22/revised PY - 2010/03/26/accepted PY - 2010/4/27/entrez PY - 2010/4/27/pubmed PY - 2012/5/23/medline SP - 437 EP - 42 JF - European journal of radiology JO - Eur J Radiol VL - 79 IS - 3 N2 - OBJECTIVE: To describe the magnetic resonance (MR) imaging findings of fetal CL/CP and evaluate its diagnostic value. METHODS AND MATERIALS: Twelve fetuses with CL/CP diagnosed by transabdominal US underwent MR imaging within 2 days of US. Half-Fourier acquisition single-shot turbo spin echo (HASTE) sequence on T2-weighted images was performed on sagittal, coronal, and axial planes anatomic to the fetuses during maternal breath holding. US and MR imaging findings were compared with final diagnoses obtained from post-natal physical examination or fetal autopsy. RESULTS: Final diagnoses confirmed incomplete midline cleft lip (n=1), unilateral cleft lip and palate (n=7), bilateral cleft lip and palate (n=1), midline cleft lip and palate (n=3). US and MR imaging diagnosed all 12 fetuses with cleft lip and the laterality. 5 (45.5%) of 11 cleft palates were identified with US, 2 of 7 fetuses with unilateral cleft palate, 2 of 3 fetuses with midline cleft palate, and one fetus with bilateral cleft palate. On MR imaging, 10 (91%) of 11 cleft palates were correctly detected. One fetus with unilateral cleft palate was not detected. No false-positives occurred. CONCLUSION: MR imaging is valuable for diagnosis of fetal CL/CP. It can demonstrate additional findings and provide more information compared with US. SN - 1872-7727 UR - https://www.unboundmedicine.com/medline/citation/20418035/Fetal_cleft_lip_with_and_without_cleft_palate:_comparison_between_MR_imaging_and_US_for_prenatal_diagnosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0720-048X(10)00143-9 DB - PRIME DP - Unbound Medicine ER -