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[Respiratory tract infection and acute deterioration of obstructive lung disease].
Ugeskr Laeger 1991; 153(19):1336-9UL

Abstract

Respiratory infection may aggravate chronic obstructive pulmonary disease. Viral respiratory infections may aggravate asthma, particularly in young individuals. Respiratory Syncytial virus and Rhinovirus dominate in children while, in adults, Influenza or Rhinovirus infections are most frequently concerned. Viral respiratory infections may also cause exacerbation of chronic bronchitis. Bacteria and their products scarcely play any part in asthmatic disease but may possibly aggravate chronic bronchitis and other forms of obstructive respiratory disease. In particular, Haemophilus influenzae and Streptococcus pneumoniae and bacterial endotoxin appear to be of significance. The mechanisms of the effects of viruses have several points of attack: Destruction of epithelium, release of mediators, potentiation of mediator-release and reduced beta-adrenergic function. Bacteria and their products may, similarly, cause bronchoconstriction and may, in vitro, release mediators and potentiate release of mediators.

Authors+Show Affiliations

Københavns Universitet, Farmakologisk Institut.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

dan

PubMed ID

2042239

Citation

Clementsen, P S., et al. "[Respiratory Tract Infection and Acute Deterioration of Obstructive Lung Disease]." Ugeskrift for Laeger, vol. 153, no. 19, 1991, pp. 1336-9.
Clementsen PS, Kristensen KS, Espersen F, et al. [Respiratory tract infection and acute deterioration of obstructive lung disease]. Ugeskr Laeg. 1991;153(19):1336-9.
Clementsen, P. S., Kristensen, K. S., Espersen, F., & Norn, S. (1991). [Respiratory tract infection and acute deterioration of obstructive lung disease]. Ugeskrift for Laeger, 153(19), pp. 1336-9.
Clementsen PS, et al. [Respiratory Tract Infection and Acute Deterioration of Obstructive Lung Disease]. Ugeskr Laeg. 1991 May 6;153(19):1336-9. PubMed PMID: 2042239.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Respiratory tract infection and acute deterioration of obstructive lung disease]. AU - Clementsen,P S, AU - Kristensen,K S, AU - Espersen,F, AU - Norn,S, PY - 1991/5/6/pubmed PY - 1991/5/6/medline PY - 1991/5/6/entrez SP - 1336 EP - 9 JF - Ugeskrift for laeger JO - Ugeskr. Laeg. VL - 153 IS - 19 N2 - Respiratory infection may aggravate chronic obstructive pulmonary disease. Viral respiratory infections may aggravate asthma, particularly in young individuals. Respiratory Syncytial virus and Rhinovirus dominate in children while, in adults, Influenza or Rhinovirus infections are most frequently concerned. Viral respiratory infections may also cause exacerbation of chronic bronchitis. Bacteria and their products scarcely play any part in asthmatic disease but may possibly aggravate chronic bronchitis and other forms of obstructive respiratory disease. In particular, Haemophilus influenzae and Streptococcus pneumoniae and bacterial endotoxin appear to be of significance. The mechanisms of the effects of viruses have several points of attack: Destruction of epithelium, release of mediators, potentiation of mediator-release and reduced beta-adrenergic function. Bacteria and their products may, similarly, cause bronchoconstriction and may, in vitro, release mediators and potentiate release of mediators. SN - 0041-5782 UR - https://www.unboundmedicine.com/medline/citation/2042239/[Respiratory_tract_infection_and_acute_deterioration_of_obstructive_lung_disease]_ L2 - https://medlineplus.gov/viralinfections.html DB - PRIME DP - Unbound Medicine ER -