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Genetic and biological characterization of avian influenza H5N1 viruses isolated from wild birds and poultry in Western Siberia.
Arch Virol. 2010 Jul; 155(7):1145-50.AV

Abstract

Three viruses included in the study were isolated from dead birds (A/duck/Omsk/1822/2006, A/chicken/Reshoty/02/2006, and A/duck/Tuva/01/2006), whereas the virus A/common gull/Chany/P/2006 was isolated from an apparently healthy gull during outbreaks of highly pathogenic avian influenza in Russia in 2006. The intravenous pathogenicity index (IVPI) of viruses A/duck/Omsk/1822/2006, A/chicken/Reshoty/02/2006, and A/duck/Tuva/01/2006 ranged from 2.7 to 3.0, while the virus A/common gull/Chany/P/2006 had a markedly lower IVPI of 1.7. The virus A/common gull/Chany/P/2006 had a unique pattern of six amino acid substitutions in the regions of viral proteins crucial for virulence of H5N1 viruses. We hypothesize that these substitutions may affect the pathogenicity of A/common gull/Chany/P/2006.

Authors+Show Affiliations

FSRI SRC VB Vector, Novosibirsk, Russia. sharshov@yandex.ruNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20432047

Citation

Sharshov, Kirill, et al. "Genetic and Biological Characterization of Avian Influenza H5N1 Viruses Isolated From Wild Birds and Poultry in Western Siberia." Archives of Virology, vol. 155, no. 7, 2010, pp. 1145-50.
Sharshov K, Romanovskaya A, Uzhachenko R, et al. Genetic and biological characterization of avian influenza H5N1 viruses isolated from wild birds and poultry in Western Siberia. Arch Virol. 2010;155(7):1145-50.
Sharshov, K., Romanovskaya, A., Uzhachenko, R., Durymanov, A., Zaykovskaya, A., Kurskaya, O., Ilinykh, P., Silko, N., Kulak, M., Alekseev, A., Zolotykh, S., Shestopalov, A., & Drozdov, I. (2010). Genetic and biological characterization of avian influenza H5N1 viruses isolated from wild birds and poultry in Western Siberia. Archives of Virology, 155(7), 1145-50. https://doi.org/10.1007/s00705-010-0676-2
Sharshov K, et al. Genetic and Biological Characterization of Avian Influenza H5N1 Viruses Isolated From Wild Birds and Poultry in Western Siberia. Arch Virol. 2010;155(7):1145-50. PubMed PMID: 20432047.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Genetic and biological characterization of avian influenza H5N1 viruses isolated from wild birds and poultry in Western Siberia. AU - Sharshov,Kirill, AU - Romanovskaya,Alesia, AU - Uzhachenko,Roman, AU - Durymanov,Alexander, AU - Zaykovskaya,Anna, AU - Kurskaya,Olga, AU - Ilinykh,Philipp, AU - Silko,Nikita, AU - Kulak,Mikhail, AU - Alekseev,Alexander, AU - Zolotykh,Sergei, AU - Shestopalov,Alexander, AU - Drozdov,Iliya, Y1 - 2010/04/30/ PY - 2009/12/17/received PY - 2010/03/23/accepted PY - 2010/5/1/entrez PY - 2010/5/1/pubmed PY - 2010/7/21/medline SP - 1145 EP - 50 JF - Archives of virology JO - Arch Virol VL - 155 IS - 7 N2 - Three viruses included in the study were isolated from dead birds (A/duck/Omsk/1822/2006, A/chicken/Reshoty/02/2006, and A/duck/Tuva/01/2006), whereas the virus A/common gull/Chany/P/2006 was isolated from an apparently healthy gull during outbreaks of highly pathogenic avian influenza in Russia in 2006. The intravenous pathogenicity index (IVPI) of viruses A/duck/Omsk/1822/2006, A/chicken/Reshoty/02/2006, and A/duck/Tuva/01/2006 ranged from 2.7 to 3.0, while the virus A/common gull/Chany/P/2006 had a markedly lower IVPI of 1.7. The virus A/common gull/Chany/P/2006 had a unique pattern of six amino acid substitutions in the regions of viral proteins crucial for virulence of H5N1 viruses. We hypothesize that these substitutions may affect the pathogenicity of A/common gull/Chany/P/2006. SN - 1432-8798 UR - https://www.unboundmedicine.com/medline/citation/20432047/Genetic_and_biological_characterization_of_avian_influenza_H5N1_viruses_isolated_from_wild_birds_and_poultry_in_Western_Siberia_ L2 - https://dx.doi.org/10.1007/s00705-010-0676-2 DB - PRIME DP - Unbound Medicine ER -