Tags

Type your tag names separated by a space and hit enter

Contribution of estimated insulin resistance and glucose intolerance to essential hypertension.
J Intern Med Suppl. 1991; 735:75-83.JI

Abstract

In a population study of 6956 middle-aged men, 5% received drug treatment for hypertension, another 25% had a blood pressure of greater than 160.90 mmHg, and 3.2% were diabetic. Prevalence of impaired glucose tolerance and diabetes was two- to threefold in hypertensive subjects, and 50% of the glucose intolerant or diabetic cases had hypertension. In 4677 unselected subjects without clinical coronary heart disease or previous diabetes, estimated insulin resistance (i.e. the 2-h insulin-to-glucose ratio during an oral glucose tolerance test, controlled for body mass index) correlated with both systolic and diastolic blood pressure. In untreated subjects, a diastolic blood pressure of greater than 90 mmHg was found in conjunction with a higher insulin resistance value than predicted, whereafter blood pressure progressively increased. The contribution of drug treatment to insulin resistance was significant, but less than 1% in the whole material and about 2.5% in cases with impaired glucose tolerance.

Authors+Show Affiliations

Department of Internal Medicine, University of Lund, Malmö General Hospital, Sweden.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2043225

Citation

Eriksson, K F., and F Lindgärde. "Contribution of Estimated Insulin Resistance and Glucose Intolerance to Essential Hypertension." Journal of Internal Medicine. Supplement, vol. 735, 1991, pp. 75-83.
Eriksson KF, Lindgärde F. Contribution of estimated insulin resistance and glucose intolerance to essential hypertension. J Intern Med Suppl. 1991;735:75-83.
Eriksson, K. F., & Lindgärde, F. (1991). Contribution of estimated insulin resistance and glucose intolerance to essential hypertension. Journal of Internal Medicine. Supplement, 735, 75-83.
Eriksson KF, Lindgärde F. Contribution of Estimated Insulin Resistance and Glucose Intolerance to Essential Hypertension. J Intern Med Suppl. 1991;735:75-83. PubMed PMID: 2043225.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Contribution of estimated insulin resistance and glucose intolerance to essential hypertension. AU - Eriksson,K F, AU - Lindgärde,F, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 75 EP - 83 JF - Journal of internal medicine. Supplement JO - J Intern Med Suppl VL - 735 N2 - In a population study of 6956 middle-aged men, 5% received drug treatment for hypertension, another 25% had a blood pressure of greater than 160.90 mmHg, and 3.2% were diabetic. Prevalence of impaired glucose tolerance and diabetes was two- to threefold in hypertensive subjects, and 50% of the glucose intolerant or diabetic cases had hypertension. In 4677 unselected subjects without clinical coronary heart disease or previous diabetes, estimated insulin resistance (i.e. the 2-h insulin-to-glucose ratio during an oral glucose tolerance test, controlled for body mass index) correlated with both systolic and diastolic blood pressure. In untreated subjects, a diastolic blood pressure of greater than 90 mmHg was found in conjunction with a higher insulin resistance value than predicted, whereafter blood pressure progressively increased. The contribution of drug treatment to insulin resistance was significant, but less than 1% in the whole material and about 2.5% in cases with impaired glucose tolerance. SN - 0955-7873 UR - https://www.unboundmedicine.com/medline/citation/2043225/Contribution_of_estimated_insulin_resistance_and_glucose_intolerance_to_essential_hypertension_ L2 - http://www.diseaseinfosearch.org/result/8360 DB - PRIME DP - Unbound Medicine ER -