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GC-MS analysis, antibacterial activity and genotoxic property of Erigeron mucronatus essential oil.
Nat Prod Commun. 2010 Apr; 5(4):621-4.NP

Abstract

GC-MS analysis of the hydrodistilled oil of Erigeron mucronatus DC was carried out, after the separation of a crystalline compound, lachnophyllum cumulene. Twenty-four components were identified. The oil contained 59.6% sesquiterpenoids, 16.1% monoterpenoids and 24.3% poly-acetylenic esters. Among the mono and sesquiterpenoids, limonene (10.3%) and caryophyllenes (11.4%) were the major constituents. The essential oil also revealed the unusual presence of both cis (8.3%) and trans (1.1%) methyl lachnophyllum esters. Seasonal variation in the yield of E. mucronatus oil was observed. The yield varied from 0.49 to 0.58%, being highest during the rainy season. Antimicrobial activity was assessed using a method based on zones of inhibition; the oil exhibited maximum anti- bacterial activity against both Staphylococcus aureus and Escherichia coli, but moderate activity against Pseudomonas aeruginosa. Genotoxicity of the oil was determined in AB blood serum at different concentrations and hours of exposure. The antibacterial activity of the oil and its insignificant genotoxicity at low concentrations make the oil a good candidate as a curative agent.

Authors+Show Affiliations

Awen BZ
Department of Medicinal Pharmacognosy, Faculty of Pharmacy, Seventh of April University, Libya.
Unnithan CR
No affiliation info available
Ravi S
No affiliation info available
Lakshmanan AJ
No affiliation info available

MeSH

Anti-Bacterial AgentsErigeronGas Chromatography-Mass SpectrometryHumansMexicoMicrobial Sensitivity TestsMutagenicity TestsOils, VolatilePlant OilsTerpenes

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20433085

Citation

Awen, Bahlul Z., et al. "GC-MS Analysis, Antibacterial Activity and Genotoxic Property of Erigeron Mucronatus Essential Oil." Natural Product Communications, vol. 5, no. 4, 2010, pp. 621-4.
Awen BZ, Unnithan CR, Ravi S, et al. GC-MS analysis, antibacterial activity and genotoxic property of Erigeron mucronatus essential oil. Nat Prod Commun. 2010;5(4):621-4.
Awen, B. Z., Unnithan, C. R., Ravi, S., & Lakshmanan, A. J. (2010). GC-MS analysis, antibacterial activity and genotoxic property of Erigeron mucronatus essential oil. Natural Product Communications, 5(4), 621-4.
Awen BZ, et al. GC-MS Analysis, Antibacterial Activity and Genotoxic Property of Erigeron Mucronatus Essential Oil. Nat Prod Commun. 2010;5(4):621-4. PubMed PMID: 20433085.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - GC-MS analysis, antibacterial activity and genotoxic property of Erigeron mucronatus essential oil. AU - Awen,Bahlul Z, AU - Unnithan,C Ramachandra, AU - Ravi,Subban, AU - Lakshmanan,Akoni J, PY - 2010/5/4/entrez PY - 2010/5/4/pubmed PY - 2010/6/2/medline SP - 621 EP - 4 JF - Natural product communications JO - Nat Prod Commun VL - 5 IS - 4 N2 - GC-MS analysis of the hydrodistilled oil of Erigeron mucronatus DC was carried out, after the separation of a crystalline compound, lachnophyllum cumulene. Twenty-four components were identified. The oil contained 59.6% sesquiterpenoids, 16.1% monoterpenoids and 24.3% poly-acetylenic esters. Among the mono and sesquiterpenoids, limonene (10.3%) and caryophyllenes (11.4%) were the major constituents. The essential oil also revealed the unusual presence of both cis (8.3%) and trans (1.1%) methyl lachnophyllum esters. Seasonal variation in the yield of E. mucronatus oil was observed. The yield varied from 0.49 to 0.58%, being highest during the rainy season. Antimicrobial activity was assessed using a method based on zones of inhibition; the oil exhibited maximum anti- bacterial activity against both Staphylococcus aureus and Escherichia coli, but moderate activity against Pseudomonas aeruginosa. Genotoxicity of the oil was determined in AB blood serum at different concentrations and hours of exposure. The antibacterial activity of the oil and its insignificant genotoxicity at low concentrations make the oil a good candidate as a curative agent. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/20433085/GC_MS_analysis_antibacterial_activity_and_genotoxic_property_of_Erigeron_mucronatus_essential_oil_ DB - PRIME DP - Unbound Medicine ER -