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Clinical and radiological outcome of craniocervical osteo-dural decompression for Chiari I-associated syringomyelia.
Neurosurg Rev. 2010 Jul; 33(3):297-303; discussion 303-4.NR

Abstract

The aim of this study was to analyze the long-term clinical and radiological outcomes of craniocervical decompression for patients affected by Chiari I-related syringomyelia. We performed a retrospective analysis of a group of patients affected by Chiari I-associated syringomyelia treated by craniocervical decompression (CCD). Surgical and technical aspects and preoperative factors predicting outcome were discussed. A total of 36 patients were reviewed. There were 17 men and 19 women (female/male ratio 1.11), and the mean age was 40.4 (range 18-68). The most important preoperative symptoms were related to myelopathy (pain, weakness, atrophy, spasticity, sensory loss, and dysesthesias). Most syrinxes were in the cervico-thoracic region (61.1%), and the majority of patients had tonsillar descent between the foramen magnum and C1. All patients underwent a craniectomy less than 3 cm in diameter followed by a duroplasty with dura substitute. No arachnoid manipulation was necessary. Three patients (8.1%) experienced cerebrospinal fluid leaks that resolved without complications. At a mean follow up of 40 months (range 16-72) 80.5% of patients exhibited improvement over their preoperative neurological examination while 11.1% stabilized. The syrinx shrank in 80.5% of patients. Chi-square test showed that preoperative syrinx extension and degree of tonsillar descent did not correlate with clinical and neuroradiological postoperative evolution. Treating syringomyelia associated in Chiari I malformation with CCD leads to a large percentage of patients with satisfying results and no irreversible complications.

Authors+Show Affiliations

Division of Neurosurgery, Civil Hospital, Alessandria, Italy. giannantonios@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20437070

Citation

Spena, Giannantonio, et al. "Clinical and Radiological Outcome of Craniocervical Osteo-dural Decompression for Chiari I-associated Syringomyelia." Neurosurgical Review, vol. 33, no. 3, 2010, pp. 297-303; discussion 303-4.
Spena G, Bernucci C, Garbossa D, et al. Clinical and radiological outcome of craniocervical osteo-dural decompression for Chiari I-associated syringomyelia. Neurosurg Rev. 2010;33(3):297-303; discussion 303-4.
Spena, G., Bernucci, C., Garbossa, D., Valfrè, W., & Versari, P. (2010). Clinical and radiological outcome of craniocervical osteo-dural decompression for Chiari I-associated syringomyelia. Neurosurgical Review, 33(3), 297-303; discussion 303-4. https://doi.org/10.1007/s10143-010-0260-y
Spena G, et al. Clinical and Radiological Outcome of Craniocervical Osteo-dural Decompression for Chiari I-associated Syringomyelia. Neurosurg Rev. 2010;33(3):297-303; discussion 303-4. PubMed PMID: 20437070.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical and radiological outcome of craniocervical osteo-dural decompression for Chiari I-associated syringomyelia. AU - Spena,Giannantonio, AU - Bernucci,Claudio, AU - Garbossa,Diego, AU - Valfrè,Walter, AU - Versari,Pietro, Y1 - 2010/05/01/ PY - 2009/08/19/received PY - 2010/03/08/accepted PY - 2010/03/07/revised PY - 2010/5/4/entrez PY - 2010/5/4/pubmed PY - 2010/9/18/medline SP - 297-303; discussion 303-4 JF - Neurosurgical review JO - Neurosurg Rev VL - 33 IS - 3 N2 - The aim of this study was to analyze the long-term clinical and radiological outcomes of craniocervical decompression for patients affected by Chiari I-related syringomyelia. We performed a retrospective analysis of a group of patients affected by Chiari I-associated syringomyelia treated by craniocervical decompression (CCD). Surgical and technical aspects and preoperative factors predicting outcome were discussed. A total of 36 patients were reviewed. There were 17 men and 19 women (female/male ratio 1.11), and the mean age was 40.4 (range 18-68). The most important preoperative symptoms were related to myelopathy (pain, weakness, atrophy, spasticity, sensory loss, and dysesthesias). Most syrinxes were in the cervico-thoracic region (61.1%), and the majority of patients had tonsillar descent between the foramen magnum and C1. All patients underwent a craniectomy less than 3 cm in diameter followed by a duroplasty with dura substitute. No arachnoid manipulation was necessary. Three patients (8.1%) experienced cerebrospinal fluid leaks that resolved without complications. At a mean follow up of 40 months (range 16-72) 80.5% of patients exhibited improvement over their preoperative neurological examination while 11.1% stabilized. The syrinx shrank in 80.5% of patients. Chi-square test showed that preoperative syrinx extension and degree of tonsillar descent did not correlate with clinical and neuroradiological postoperative evolution. Treating syringomyelia associated in Chiari I malformation with CCD leads to a large percentage of patients with satisfying results and no irreversible complications. SN - 1437-2320 UR - https://www.unboundmedicine.com/medline/citation/20437070/Clinical_and_radiological_outcome_of_craniocervical_osteo_dural_decompression_for_Chiari_I_associated_syringomyelia_ L2 - https://dx.doi.org/10.1007/s10143-010-0260-y DB - PRIME DP - Unbound Medicine ER -