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In vitro antimicrobial, antioxidant, and antispasmodic activities and the composition of the essential oil of Origanum acutidens (Hand.-Mazz.) Ietswaart.
J Med Food. 2010 Jun; 13(3):705-9.JM

Abstract

The radical scavenging, antimicrobial, and antispasmodic activities and the composition of Origanum acutidens (Hand.-Mazz.) Ietswaart (Order Labiatte) essential oil were evaluated in vitro. Gas chromatography/mass spectrometry analysis of the oil resulted in the identification of 20 compounds, representing 93.61% of the oil; carvacrol (65%) was the main component. The sample was also subjected to a screening for antioxidant activity by using the 1,1-diphenyl-2-picrylhydrazyl and beta-carotene/linoleic acid assays. The essential oil exhibited strong antioxidant activity. Using the agar disk diffusion method, antimicrobial activities of the essential oils were determined for nine microorganisms; antimicrobial activity was shown against eight of them. O. acutidens oil exhibited spontaneous contractions in rat ileum at the 100% level at 0.1 mg/mL level.

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Authors+Show Affiliations

Goze I
Vocational School of Health Services, Cumhuriyet University, Sivas, Turkey. igoze58@mynet.com
Alim A
No affiliation info available
Cetinus SA
No affiliation info available
Cetin A
No affiliation info available
Durmus N
No affiliation info available
Atas AT
No affiliation info available
Vural N
No affiliation info available

MeSH

AnimalsAnti-Infective AgentsAntioxidantsBacteriaCandida albicansIleumIn Vitro TechniquesMaleMuscle ContractionOils, VolatileOriganumParasympatholyticsPlant OilsRatsRats, Wistar

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20438322

Citation

Goze, Ismihan, et al. "In Vitro Antimicrobial, Antioxidant, and Antispasmodic Activities and the Composition of the Essential Oil of Origanum Acutidens (Hand.-Mazz.) Ietswaart." Journal of Medicinal Food, vol. 13, no. 3, 2010, pp. 705-9.
Goze I, Alim A, Cetinus SA, et al. In vitro antimicrobial, antioxidant, and antispasmodic activities and the composition of the essential oil of Origanum acutidens (Hand.-Mazz.) Ietswaart. J Med Food. 2010;13(3):705-9.
Goze, I., Alim, A., Cetinus, S. A., Cetin, A., Durmus, N., Atas, A. T., & Vural, N. (2010). In vitro antimicrobial, antioxidant, and antispasmodic activities and the composition of the essential oil of Origanum acutidens (Hand.-Mazz.) Ietswaart. Journal of Medicinal Food, 13(3), 705-9. https://doi.org/10.1089/jmf.2009.0094
Goze I, et al. In Vitro Antimicrobial, Antioxidant, and Antispasmodic Activities and the Composition of the Essential Oil of Origanum Acutidens (Hand.-Mazz.) Ietswaart. J Med Food. 2010;13(3):705-9. PubMed PMID: 20438322.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In vitro antimicrobial, antioxidant, and antispasmodic activities and the composition of the essential oil of Origanum acutidens (Hand.-Mazz.) Ietswaart. AU - Goze,Ismihan, AU - Alim,Ahmet, AU - Cetinus,Senay Akkus, AU - Cetin,Ali, AU - Durmus,Nedim, AU - Atas,Ahmet Turan, AU - Vural,Nilufer, PY - 2010/5/5/entrez PY - 2010/5/5/pubmed PY - 2010/8/28/medline SP - 705 EP - 9 JF - Journal of medicinal food JO - J Med Food VL - 13 IS - 3 N2 - The radical scavenging, antimicrobial, and antispasmodic activities and the composition of Origanum acutidens (Hand.-Mazz.) Ietswaart (Order Labiatte) essential oil were evaluated in vitro. Gas chromatography/mass spectrometry analysis of the oil resulted in the identification of 20 compounds, representing 93.61% of the oil; carvacrol (65%) was the main component. The sample was also subjected to a screening for antioxidant activity by using the 1,1-diphenyl-2-picrylhydrazyl and beta-carotene/linoleic acid assays. The essential oil exhibited strong antioxidant activity. Using the agar disk diffusion method, antimicrobial activities of the essential oils were determined for nine microorganisms; antimicrobial activity was shown against eight of them. O. acutidens oil exhibited spontaneous contractions in rat ileum at the 100% level at 0.1 mg/mL level. SN - 1557-7600 UR - https://www.unboundmedicine.com/medline/citation/20438322/In_vitro_antimicrobial_antioxidant_and_antispasmodic_activities_and_the_composition_of_the_essential_oil_of_Origanum_acutidens__Hand__Mazz___Ietswaart_ L2 - https://www.liebertpub.com/doi/10.1089/jmf.2009.0094?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -
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