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High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey Replication.
Arch Gen Psychiatry. 2010 May; 67(5):489-96.AG

Abstract

CONTEXT

Little is known about prevalence rates of DSM-IV disorders across age strata of older adults, including common conditions such as individual and coexisting mood and anxiety disorders.

OBJECTIVE

To determine nationally representative estimates of 12-month prevalence rates of mood, anxiety, and comorbid mood-anxiety disorders across young-old, mid-old, old-old, and oldest-old community-dwelling adults.

DESIGN

The National Comorbidity Survey Replication (NCS-R) is a population-based probability sample of 9282 participants 18 years and older, conducted between February 2001 and April 2003. The NCS-R survey used the fully structured World Health Organization World Mental Health Survey version of the Composite International Diagnostic Interview.

SETTING

Continental United States.

PARTICIPANTS

We studied the 2575 participants 55 years and older who were part of NCS-R (43%, 55-64 years; 32%, 65-74 years; 20%, 75-84 years; 5%, >or=85 years). This included only noninstitutionalized adults, as all NCS-R participants resided in households within the community.

MAIN OUTCOME MEASURES

Twelve-month prevalence of mood disorders (major depressive disorder, dysthymia, bipolar disorder), anxiety disorders (panic disorder, agoraphobia, specific phobia, social phobia, generalized anxiety disorder, posttraumatic stress disorder), and coexisting mood-anxiety disorder were assessed using DSM-IV criteria. Prevalence rates were weighted to adjust for the complex design to infer generalizability to the US population.

RESULTS

The likelihood of having a mood, anxiety, or combined mood-anxiety disorder generally showed a pattern of decline with age (P < .05). Twelve-month disorders showed higher rates in women compared with men, a statistically significant trend with age. In addition, anxiety disorders were as high if not higher than mood disorders across age groups (overall 12-month rates: mood, 5% and anxiety, 12%). No differences were found between race/ethnicity groups.

CONCLUSION

Prevalence rates of DSM-IV mood and anxiety disorders in late life tend to decline with age, but remain very common, especially in women. These results highlight the need for intervention and prevention strategies.

Authors+Show Affiliations

Department of Psychiatry, University of California, San Francisco, San Francisco, San Francisco, CA 94121, USA. amy.byers@ucsf.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20439830

Citation

Byers, Amy L., et al. "High Occurrence of Mood and Anxiety Disorders Among Older Adults: the National Comorbidity Survey Replication." Archives of General Psychiatry, vol. 67, no. 5, 2010, pp. 489-96.
Byers AL, Yaffe K, Covinsky KE, et al. High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey Replication. Arch Gen Psychiatry. 2010;67(5):489-96.
Byers, A. L., Yaffe, K., Covinsky, K. E., Friedman, M. B., & Bruce, M. L. (2010). High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey Replication. Archives of General Psychiatry, 67(5), 489-96. https://doi.org/10.1001/archgenpsychiatry.2010.35
Byers AL, et al. High Occurrence of Mood and Anxiety Disorders Among Older Adults: the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2010;67(5):489-96. PubMed PMID: 20439830.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey Replication. AU - Byers,Amy L, AU - Yaffe,Kristine, AU - Covinsky,Kenneth E, AU - Friedman,Michael B, AU - Bruce,Martha L, PY - 2010/5/5/entrez PY - 2010/5/5/pubmed PY - 2010/5/18/medline SP - 489 EP - 96 JF - Archives of general psychiatry JO - Arch Gen Psychiatry VL - 67 IS - 5 N2 - CONTEXT: Little is known about prevalence rates of DSM-IV disorders across age strata of older adults, including common conditions such as individual and coexisting mood and anxiety disorders. OBJECTIVE: To determine nationally representative estimates of 12-month prevalence rates of mood, anxiety, and comorbid mood-anxiety disorders across young-old, mid-old, old-old, and oldest-old community-dwelling adults. DESIGN: The National Comorbidity Survey Replication (NCS-R) is a population-based probability sample of 9282 participants 18 years and older, conducted between February 2001 and April 2003. The NCS-R survey used the fully structured World Health Organization World Mental Health Survey version of the Composite International Diagnostic Interview. SETTING: Continental United States. PARTICIPANTS: We studied the 2575 participants 55 years and older who were part of NCS-R (43%, 55-64 years; 32%, 65-74 years; 20%, 75-84 years; 5%, >or=85 years). This included only noninstitutionalized adults, as all NCS-R participants resided in households within the community. MAIN OUTCOME MEASURES: Twelve-month prevalence of mood disorders (major depressive disorder, dysthymia, bipolar disorder), anxiety disorders (panic disorder, agoraphobia, specific phobia, social phobia, generalized anxiety disorder, posttraumatic stress disorder), and coexisting mood-anxiety disorder were assessed using DSM-IV criteria. Prevalence rates were weighted to adjust for the complex design to infer generalizability to the US population. RESULTS: The likelihood of having a mood, anxiety, or combined mood-anxiety disorder generally showed a pattern of decline with age (P < .05). Twelve-month disorders showed higher rates in women compared with men, a statistically significant trend with age. In addition, anxiety disorders were as high if not higher than mood disorders across age groups (overall 12-month rates: mood, 5% and anxiety, 12%). No differences were found between race/ethnicity groups. CONCLUSION: Prevalence rates of DSM-IV mood and anxiety disorders in late life tend to decline with age, but remain very common, especially in women. These results highlight the need for intervention and prevention strategies. SN - 1538-3636 UR - https://www.unboundmedicine.com/medline/citation/20439830/High_occurrence_of_mood_and_anxiety_disorders_among_older_adults:_The_National_Comorbidity_Survey_Replication_ L2 - https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/archgenpsychiatry.2010.35 DB - PRIME DP - Unbound Medicine ER -