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Lyme neuroborreliosis: aetiology and diagnosis of facial palsy in children from Tyrol.
Klin Padiatr. 2010 Sep; 222(5):302-7.KP

Abstract

BACKGROUND

Lyme neuroborreliosis (LNB) is the second most common manifestation of Borrelia burgdorferi sensu lato (s. l.) infection in Europe. LNB is difficult to differentiate from other aetiologies of aseptic meningitis. Diagnostic criteria for LNB in children are not established. Therfore, based on the epidemiology of LNB in children from Tyrol, the aim of our study was to point out the necessity of a clear definition of pediatric LNB to avoid underdiagnosis and overtreatment.

PATIENTS AND METHODS

All medical charts of patients presented with acute peripheral facial palsy from January 2002 to December 2005 were reviewed. The patients were rediagnosed according to the criteria of the German Society of Neurology (DGN).

RESULTS

We identified 66 patients with peripheral facial palsy. 30 children were handled as B. burgdorferi s. l. infection. 5 patients were overtreated with antibiotic therapy. After reevaluation according to the DGN criteria 7 cases were reclassified as possible, 16 cases as probable and 7 cases as confirmed LNB.

CONCLUSIONS

Utilization of the established DGN criteria for pediatric LNB might help to elucidate the propability of LNB. Prospective studies are required to establish a classification system. A diagnostic tool, based on laboratory and clinical data, should avoid overtreatment of pediatric LNB.

Authors+Show Affiliations

Department of Pediatrics, Medical University Innsbruck, Austria. juergen.brunner@uki.atNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20455197

Citation

Brunner, J, et al. "Lyme Neuroborreliosis: Aetiology and Diagnosis of Facial Palsy in Children From Tyrol." Klinische Padiatrie, vol. 222, no. 5, 2010, pp. 302-7.
Brunner J, Moschovakis G, Prelog M, et al. Lyme neuroborreliosis: aetiology and diagnosis of facial palsy in children from Tyrol. Klin Padiatr. 2010;222(5):302-7.
Brunner, J., Moschovakis, G., Prelog, M., Walder, G., Wuerzner, R., & Zimmerhackl, L. B. (2010). Lyme neuroborreliosis: aetiology and diagnosis of facial palsy in children from Tyrol. Klinische Padiatrie, 222(5), 302-7. https://doi.org/10.1055/s-0030-1249091
Brunner J, et al. Lyme Neuroborreliosis: Aetiology and Diagnosis of Facial Palsy in Children From Tyrol. Klin Padiatr. 2010;222(5):302-7. PubMed PMID: 20455197.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lyme neuroborreliosis: aetiology and diagnosis of facial palsy in children from Tyrol. AU - Brunner,J, AU - Moschovakis,G, AU - Prelog,M, AU - Walder,G, AU - Wuerzner,R, AU - Zimmerhackl,L B, Y1 - 2010/05/07/ PY - 2010/5/11/entrez PY - 2010/5/11/pubmed PY - 2011/2/1/medline SP - 302 EP - 7 JF - Klinische Padiatrie JO - Klin Padiatr VL - 222 IS - 5 N2 - BACKGROUND: Lyme neuroborreliosis (LNB) is the second most common manifestation of Borrelia burgdorferi sensu lato (s. l.) infection in Europe. LNB is difficult to differentiate from other aetiologies of aseptic meningitis. Diagnostic criteria for LNB in children are not established. Therfore, based on the epidemiology of LNB in children from Tyrol, the aim of our study was to point out the necessity of a clear definition of pediatric LNB to avoid underdiagnosis and overtreatment. PATIENTS AND METHODS: All medical charts of patients presented with acute peripheral facial palsy from January 2002 to December 2005 were reviewed. The patients were rediagnosed according to the criteria of the German Society of Neurology (DGN). RESULTS: We identified 66 patients with peripheral facial palsy. 30 children were handled as B. burgdorferi s. l. infection. 5 patients were overtreated with antibiotic therapy. After reevaluation according to the DGN criteria 7 cases were reclassified as possible, 16 cases as probable and 7 cases as confirmed LNB. CONCLUSIONS: Utilization of the established DGN criteria for pediatric LNB might help to elucidate the propability of LNB. Prospective studies are required to establish a classification system. A diagnostic tool, based on laboratory and clinical data, should avoid overtreatment of pediatric LNB. SN - 1439-3824 UR - https://www.unboundmedicine.com/medline/citation/20455197/Lyme_neuroborreliosis:_aetiology_and_diagnosis_of_facial_palsy_in_children_from_Tyrol_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-0030-1249091 DB - PRIME DP - Unbound Medicine ER -