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The importance of a differential diagnosis between true hemifacial microsomia and pseudo-hemifacial microsomia in the post-surgical long-term prognosis.
J Craniomaxillofac Surg. 2011 Jan; 39(1):10-6.JC

Abstract

Long-term results after surgical treatment of the mandibular asymmetry in growing children with hemifacial microsomia (HFM), whether with osteotomies or distraction osteogenesis, have mostly shown a tendency towards the recurrence of the asymmetry. In contrast, in the literature we find sporadic case reports where the long-term post-surgical follow-up of patients diagnosed as HFM, are surprisingly stable. All these reports refer to patients who have substantially no soft tissue involvement, but only severe mandibular ramus and condyle deformities. The phenotypes of these cases are unexpectedly similar. The authors suggest, that it is possible that all of these cases might be isolated hemimandibular hypoplasias, misdiagnosed as HFM, which present a normal functional matrix and, therefore, tend to grow towards the original symmetry. Differential diagnosis between true HFM and this HFM-like isolated hemimandibular hypoplasia (pseudo-HFM) is of great importance given the very different prognosis and it is possible through the collaboration between not only surgeons and orthodontists, but also of geneticists and dysmorphologists.

Authors+Show Affiliations

Department of Maxillofacial Surgery, Cleft lip and palate Center, University of Milano, Italy. cmeazzini@yahoo.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20456963

Citation

Meazzini, Maria C., et al. "The Importance of a Differential Diagnosis Between True Hemifacial Microsomia and Pseudo-hemifacial Microsomia in the Post-surgical Long-term Prognosis." Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery, vol. 39, no. 1, 2011, pp. 10-6.
Meazzini MC, Brusati R, Diner P, et al. The importance of a differential diagnosis between true hemifacial microsomia and pseudo-hemifacial microsomia in the post-surgical long-term prognosis. J Craniomaxillofac Surg. 2011;39(1):10-6.
Meazzini, M. C., Brusati, R., Diner, P., Giannì, E., Lalatta, F., Magri, A. S., Picard, A., & Sesenna, E. (2011). The importance of a differential diagnosis between true hemifacial microsomia and pseudo-hemifacial microsomia in the post-surgical long-term prognosis. Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery, 39(1), 10-6. https://doi.org/10.1016/j.jcms.2010.03.003
Meazzini MC, et al. The Importance of a Differential Diagnosis Between True Hemifacial Microsomia and Pseudo-hemifacial Microsomia in the Post-surgical Long-term Prognosis. J Craniomaxillofac Surg. 2011;39(1):10-6. PubMed PMID: 20456963.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The importance of a differential diagnosis between true hemifacial microsomia and pseudo-hemifacial microsomia in the post-surgical long-term prognosis. AU - Meazzini,Maria C, AU - Brusati,Roberto, AU - Diner,Patrik, AU - Giannì,Ennio, AU - Lalatta,Faustina, AU - Magri,Alice S, AU - Picard,Arnaud, AU - Sesenna,Enrico, Y1 - 2010/04/24/ PY - 2009/07/13/received PY - 2010/03/05/revised PY - 2010/03/09/accepted PY - 2010/5/12/entrez PY - 2010/5/12/pubmed PY - 2011/6/3/medline SP - 10 EP - 6 JF - Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery JO - J Craniomaxillofac Surg VL - 39 IS - 1 N2 - Long-term results after surgical treatment of the mandibular asymmetry in growing children with hemifacial microsomia (HFM), whether with osteotomies or distraction osteogenesis, have mostly shown a tendency towards the recurrence of the asymmetry. In contrast, in the literature we find sporadic case reports where the long-term post-surgical follow-up of patients diagnosed as HFM, are surprisingly stable. All these reports refer to patients who have substantially no soft tissue involvement, but only severe mandibular ramus and condyle deformities. The phenotypes of these cases are unexpectedly similar. The authors suggest, that it is possible that all of these cases might be isolated hemimandibular hypoplasias, misdiagnosed as HFM, which present a normal functional matrix and, therefore, tend to grow towards the original symmetry. Differential diagnosis between true HFM and this HFM-like isolated hemimandibular hypoplasia (pseudo-HFM) is of great importance given the very different prognosis and it is possible through the collaboration between not only surgeons and orthodontists, but also of geneticists and dysmorphologists. SN - 1878-4119 UR - https://www.unboundmedicine.com/medline/citation/20456963/The_importance_of_a_differential_diagnosis_between_true_hemifacial_microsomia_and_pseudo_hemifacial_microsomia_in_the_post_surgical_long_term_prognosis_ DB - PRIME DP - Unbound Medicine ER -