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Asymmetric synthesis of cyclic cis-beta-amino acid derivatives using sulfinimines and prochiral Weinreb amide enolates.
J Org Chem. 2010 Jun 04; 75(11):3814-20.JO

Abstract

Cyclic cis-beta-amino Weinreb amides, valuable building blocks for the asymmetric synthesis of cyclic beta-amino acids derivatives, are readily prepared via ring-closing metathesis of sulfinimine-derived N-sulfinyl beta-amino diene Weinreb amides. These unsaturated cyclic cis-beta-amino Weinreb amides are valuable building blocks for the asymmetric synthesis of cyclic beta-amino acid derivatives.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Davis FA
Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA. fdavis@temple.edu
Theddu N
No affiliation info available

MeSH

AmidesAmino AcidsCyclizationIminesSulfonium Compounds

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

20462208

Citation

Davis, Franklin A., and Naresh Theddu. "Asymmetric Synthesis of Cyclic Cis-beta-amino Acid Derivatives Using Sulfinimines and Prochiral Weinreb Amide Enolates." The Journal of Organic Chemistry, vol. 75, no. 11, 2010, pp. 3814-20.
Davis FA, Theddu N. Asymmetric synthesis of cyclic cis-beta-amino acid derivatives using sulfinimines and prochiral Weinreb amide enolates. J Org Chem. 2010;75(11):3814-20.
Davis, F. A., & Theddu, N. (2010). Asymmetric synthesis of cyclic cis-beta-amino acid derivatives using sulfinimines and prochiral Weinreb amide enolates. The Journal of Organic Chemistry, 75(11), 3814-20. https://doi.org/10.1021/jo100680b
Davis FA, Theddu N. Asymmetric Synthesis of Cyclic Cis-beta-amino Acid Derivatives Using Sulfinimines and Prochiral Weinreb Amide Enolates. J Org Chem. 2010 Jun 4;75(11):3814-20. PubMed PMID: 20462208.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Asymmetric synthesis of cyclic cis-beta-amino acid derivatives using sulfinimines and prochiral Weinreb amide enolates. AU - Davis,Franklin A, AU - Theddu,Naresh, PY - 2010/5/14/entrez PY - 2010/5/14/pubmed PY - 2010/9/4/medline SP - 3814 EP - 20 JF - The Journal of organic chemistry JO - J Org Chem VL - 75 IS - 11 N2 - Cyclic cis-beta-amino Weinreb amides, valuable building blocks for the asymmetric synthesis of cyclic beta-amino acids derivatives, are readily prepared via ring-closing metathesis of sulfinimine-derived N-sulfinyl beta-amino diene Weinreb amides. These unsaturated cyclic cis-beta-amino Weinreb amides are valuable building blocks for the asymmetric synthesis of cyclic beta-amino acid derivatives. SN - 1520-6904 UR - https://www.unboundmedicine.com/medline/citation/20462208/Asymmetric_synthesis_of_cyclic_cis_beta_amino_acid_derivatives_using_sulfinimines_and_prochiral_Weinreb_amide_enolates_ L2 - https://doi.org/10.1021/jo100680b DB - PRIME DP - Unbound Medicine ER -