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Clinical study of repigmentation patterns with either narrow-band ultraviolet B (NBUVB) or 308 nm excimer laser treatment in Korean vitiligo patients.
Int J Dermatol. 2010 Mar; 49(3):317-23.IJ

Abstract

BACKGROUND

Various repigmentation patterns such as perifollicular, marginal, diffuse, and mixed configuration can occur in vitiligo. The aim of this study was to clinically assess the types of repigmentation patterns obtained with narrow-band ultraviolet B (NBUVB) phototherapy or targeted phototherapy using a 308 nm excimer laser and to reveal whether the repigmentation patterns have any relationship to the location of lesions, patient's age, duration of lesions, or speed of improvement.

METHODS

This study enrolled 51 patients who had effective responses as compared with baseline when treated with NBUVB alone and 52 patients who had effective responses as compared with baseline when treated with excimer laser alone. We evaluated the repigmentation patterns when the responses to treatments appeared.

RESULTS

The most frequent repigmentation pattern was the perifollicular type in both groups treated with NBUVB (42.2%) or excimer laser (51.3%), followed by marginal, diffuse, and combined, in that order. There was no significant difference in the repigmentation pattern according to the location of lesions, patient's age, or duration of lesions. The marginal pattern was predominant in both NBUVB and excimer laser-treated groups when excellent responses (more than 75% repigmentation achieved at 12 weeks) appeared.

CONCLUSIONS

The repigmentation patterns according to location, age, duration of lesions, and speed of response showed similarities in both the NBUVB and excimer laser-treated groups.

Authors+Show Affiliations

Department of Dermatology, School of Medicine, Kyunghee University, Seoul, Korea.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

20465673

Citation

Yang, Yun-Seok, et al. "Clinical Study of Repigmentation Patterns With Either Narrow-band Ultraviolet B (NBUVB) or 308 Nm Excimer Laser Treatment in Korean Vitiligo Patients." International Journal of Dermatology, vol. 49, no. 3, 2010, pp. 317-23.
Yang YS, Cho HR, Ryou JH, et al. Clinical study of repigmentation patterns with either narrow-band ultraviolet B (NBUVB) or 308 nm excimer laser treatment in Korean vitiligo patients. Int J Dermatol. 2010;49(3):317-23.
Yang, Y. S., Cho, H. R., Ryou, J. H., & Lee, M. H. (2010). Clinical study of repigmentation patterns with either narrow-band ultraviolet B (NBUVB) or 308 nm excimer laser treatment in Korean vitiligo patients. International Journal of Dermatology, 49(3), 317-23. https://doi.org/10.1111/j.1365-4632.2009.04332.x
Yang YS, et al. Clinical Study of Repigmentation Patterns With Either Narrow-band Ultraviolet B (NBUVB) or 308 Nm Excimer Laser Treatment in Korean Vitiligo Patients. Int J Dermatol. 2010;49(3):317-23. PubMed PMID: 20465673.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical study of repigmentation patterns with either narrow-band ultraviolet B (NBUVB) or 308 nm excimer laser treatment in Korean vitiligo patients. AU - Yang,Yun-Seok, AU - Cho,Hee-Ryung, AU - Ryou,Ji-Ho, AU - Lee,Mu-Hyoung, PY - 2010/5/15/entrez PY - 2010/5/15/pubmed PY - 2010/8/25/medline SP - 317 EP - 23 JF - International journal of dermatology JO - Int. J. Dermatol. VL - 49 IS - 3 N2 - BACKGROUND: Various repigmentation patterns such as perifollicular, marginal, diffuse, and mixed configuration can occur in vitiligo. The aim of this study was to clinically assess the types of repigmentation patterns obtained with narrow-band ultraviolet B (NBUVB) phototherapy or targeted phototherapy using a 308 nm excimer laser and to reveal whether the repigmentation patterns have any relationship to the location of lesions, patient's age, duration of lesions, or speed of improvement. METHODS: This study enrolled 51 patients who had effective responses as compared with baseline when treated with NBUVB alone and 52 patients who had effective responses as compared with baseline when treated with excimer laser alone. We evaluated the repigmentation patterns when the responses to treatments appeared. RESULTS: The most frequent repigmentation pattern was the perifollicular type in both groups treated with NBUVB (42.2%) or excimer laser (51.3%), followed by marginal, diffuse, and combined, in that order. There was no significant difference in the repigmentation pattern according to the location of lesions, patient's age, or duration of lesions. The marginal pattern was predominant in both NBUVB and excimer laser-treated groups when excellent responses (more than 75% repigmentation achieved at 12 weeks) appeared. CONCLUSIONS: The repigmentation patterns according to location, age, duration of lesions, and speed of response showed similarities in both the NBUVB and excimer laser-treated groups. SN - 1365-4632 UR - https://www.unboundmedicine.com/medline/citation/20465673/Clinical_study_of_repigmentation_patterns_with_either_narrow_band_ultraviolet_B__NBUVB__or_308_nm_excimer_laser_treatment_in_Korean_vitiligo_patients_ L2 - https://doi.org/10.1111/j.1365-4632.2009.04332.x DB - PRIME DP - Unbound Medicine ER -