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Anodic oxidation of ketoprofen-an anti-inflammatory drug using boron doped diamond and platinum electrodes.
J Hazard Mater. 2010 Aug 15; 180(1-3):753-8.JH

Abstract

The mineralization of ketoprofen (KP) by anodic oxidation was studied by employing boron doped diamond (BDD) and Pt electrodes. The redox behavior of KP molecule, fouling of electrodes, generation of oxygen and active chlorine species were studied by cyclic voltammetry. The effect of electrolyte, pH of aqueous medium and applied current density on the mineralization behavior of KP was also investigated. The degradation and mineralization were monitored by UV-vis spectrophotometer and total organic carbon analyzer, respectively. The results were explained in terms of in situ generation of hydroxyl radical (OH), peroxodisulfate (S(2)O(8)(2-)), and active chlorine species (Cl(2), HOCl, OCl(-)). The physisorbed OH on BDD was observed to trigger the combustion of KP in to CO(2) and H(2)O. The poor mineralization at both BDD and Pt anodes in the presence of NaCl as supporting electrolyte was ascribed to the formation of chlorinated organic compounds which are refractory. Complete mineralization of KP molecule was achieved using Na(2)SO(4) as supporting electrolyte.

Authors+Show Affiliations

National Metallurgical Laboratory Madras Centre, CSIR Madras Complex, Taramani, Chennai, India. muruga.chem@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20488617

Citation

Murugananthan, M, et al. "Anodic Oxidation of Ketoprofen-an Anti-inflammatory Drug Using Boron Doped Diamond and Platinum Electrodes." Journal of Hazardous Materials, vol. 180, no. 1-3, 2010, pp. 753-8.
Murugananthan M, Latha SS, Bhaskar Raju G, et al. Anodic oxidation of ketoprofen-an anti-inflammatory drug using boron doped diamond and platinum electrodes. J Hazard Mater. 2010;180(1-3):753-8.
Murugananthan, M., Latha, S. S., Bhaskar Raju, G., & Yoshihara, S. (2010). Anodic oxidation of ketoprofen-an anti-inflammatory drug using boron doped diamond and platinum electrodes. Journal of Hazardous Materials, 180(1-3), 753-8. https://doi.org/10.1016/j.jhazmat.2010.05.007
Murugananthan M, et al. Anodic Oxidation of Ketoprofen-an Anti-inflammatory Drug Using Boron Doped Diamond and Platinum Electrodes. J Hazard Mater. 2010 Aug 15;180(1-3):753-8. PubMed PMID: 20488617.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anodic oxidation of ketoprofen-an anti-inflammatory drug using boron doped diamond and platinum electrodes. AU - Murugananthan,M, AU - Latha,S S, AU - Bhaskar Raju,G, AU - Yoshihara,S, Y1 - 2010/05/08/ PY - 2010/01/06/received PY - 2010/04/07/revised PY - 2010/05/04/accepted PY - 2010/5/22/entrez PY - 2010/5/22/pubmed PY - 2010/9/3/medline SP - 753 EP - 8 JF - Journal of hazardous materials JO - J Hazard Mater VL - 180 IS - 1-3 N2 - The mineralization of ketoprofen (KP) by anodic oxidation was studied by employing boron doped diamond (BDD) and Pt electrodes. The redox behavior of KP molecule, fouling of electrodes, generation of oxygen and active chlorine species were studied by cyclic voltammetry. The effect of electrolyte, pH of aqueous medium and applied current density on the mineralization behavior of KP was also investigated. The degradation and mineralization were monitored by UV-vis spectrophotometer and total organic carbon analyzer, respectively. The results were explained in terms of in situ generation of hydroxyl radical (OH), peroxodisulfate (S(2)O(8)(2-)), and active chlorine species (Cl(2), HOCl, OCl(-)). The physisorbed OH on BDD was observed to trigger the combustion of KP in to CO(2) and H(2)O. The poor mineralization at both BDD and Pt anodes in the presence of NaCl as supporting electrolyte was ascribed to the formation of chlorinated organic compounds which are refractory. Complete mineralization of KP molecule was achieved using Na(2)SO(4) as supporting electrolyte. SN - 1873-3336 UR - https://www.unboundmedicine.com/medline/citation/20488617/Anodic_oxidation_of_ketoprofen_an_anti_inflammatory_drug_using_boron_doped_diamond_and_platinum_electrodes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0304-3894(10)00587-X DB - PRIME DP - Unbound Medicine ER -