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Pretreatment malnutrition and quality of life - association with prolonged length of hospital stay among patients with gynecological cancer: a cohort study.
BMC Cancer. 2010 May 25; 10:232.BC

Abstract

BACKGROUND

Length of hospital stay (LOS) is a surrogate marker for patients' well-being during hospital treatment and is associated with health care costs. Identifying pretreatment factors associated with LOS in surgical patients may enable early intervention in order to reduce postoperative LOS.

METHODS

This cohort study enrolled 157 patients with suspected or proven gynecological cancer at a tertiary cancer centre (2004-2006). Before commencing treatment, the scored Patient Generated - Subjective Global Assessment (PG-SGA) measuring nutritional status and the Functional Assessment of Cancer Therapy-General (FACT-G) scale measuring quality of life (QOL) were completed. Clinical and demographic patient characteristics were prospectively obtained. Patients were grouped into those with prolonged LOS if their hospital stay was greater than the median LOS and those with average or below average LOS.

RESULTS

Patients' mean age was 58 years (SD 14 years). Preoperatively, 81 (52%) patients presented with suspected benign disease/pelvic mass, 23 (15%) with suspected advanced ovarian cancer, 36 (23%) patients with suspected endometrial and 17 (11%) with cervical cancer, respectively. In univariate models prolonged LOS was associated with low serum albumin or hemoglobin, malnutrition (PG-SGA score and PG-SGA group B or C), low pretreatment FACT-G score, and suspected diagnosis of cancer. In multivariable models, PG-SGA group B or C, FACT-G score and suspected diagnosis of advanced ovarian cancer independently predicted LOS.

CONCLUSIONS

Malnutrition, low quality of life scores and being diagnosed with advanced ovarian cancer are the major determinants of prolonged LOS amongst gynecological cancer patients. Interventions addressing malnutrition and poor QOL may decrease LOS in gynecological cancer patients.

Authors+Show Affiliations

Queensland Centre for Gynaecological Cancer, Level 6 Ned Hanlon Building, The Royal Brisbane and Women's Hospital, Herston Queensland 4029, Australia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20497581

Citation

Laky, Brenda, et al. "Pretreatment Malnutrition and Quality of Life - Association With Prolonged Length of Hospital Stay Among Patients With Gynecological Cancer: a Cohort Study." BMC Cancer, vol. 10, 2010, p. 232.
Laky B, Janda M, Kondalsamy-Chennakesavan S, et al. Pretreatment malnutrition and quality of life - association with prolonged length of hospital stay among patients with gynecological cancer: a cohort study. BMC Cancer. 2010;10:232.
Laky, B., Janda, M., Kondalsamy-Chennakesavan, S., Cleghorn, G., & Obermair, A. (2010). Pretreatment malnutrition and quality of life - association with prolonged length of hospital stay among patients with gynecological cancer: a cohort study. BMC Cancer, 10, 232. https://doi.org/10.1186/1471-2407-10-232
Laky B, et al. Pretreatment Malnutrition and Quality of Life - Association With Prolonged Length of Hospital Stay Among Patients With Gynecological Cancer: a Cohort Study. BMC Cancer. 2010 May 25;10:232. PubMed PMID: 20497581.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pretreatment malnutrition and quality of life - association with prolonged length of hospital stay among patients with gynecological cancer: a cohort study. AU - Laky,Brenda, AU - Janda,Monika, AU - Kondalsamy-Chennakesavan,Srinivas, AU - Cleghorn,Geoffrey, AU - Obermair,Andreas, Y1 - 2010/05/25/ PY - 2009/10/13/received PY - 2010/05/25/accepted PY - 2010/5/26/entrez PY - 2010/5/26/pubmed PY - 2010/8/17/medline SP - 232 EP - 232 JF - BMC cancer JO - BMC Cancer VL - 10 N2 - BACKGROUND: Length of hospital stay (LOS) is a surrogate marker for patients' well-being during hospital treatment and is associated with health care costs. Identifying pretreatment factors associated with LOS in surgical patients may enable early intervention in order to reduce postoperative LOS. METHODS: This cohort study enrolled 157 patients with suspected or proven gynecological cancer at a tertiary cancer centre (2004-2006). Before commencing treatment, the scored Patient Generated - Subjective Global Assessment (PG-SGA) measuring nutritional status and the Functional Assessment of Cancer Therapy-General (FACT-G) scale measuring quality of life (QOL) were completed. Clinical and demographic patient characteristics were prospectively obtained. Patients were grouped into those with prolonged LOS if their hospital stay was greater than the median LOS and those with average or below average LOS. RESULTS: Patients' mean age was 58 years (SD 14 years). Preoperatively, 81 (52%) patients presented with suspected benign disease/pelvic mass, 23 (15%) with suspected advanced ovarian cancer, 36 (23%) patients with suspected endometrial and 17 (11%) with cervical cancer, respectively. In univariate models prolonged LOS was associated with low serum albumin or hemoglobin, malnutrition (PG-SGA score and PG-SGA group B or C), low pretreatment FACT-G score, and suspected diagnosis of cancer. In multivariable models, PG-SGA group B or C, FACT-G score and suspected diagnosis of advanced ovarian cancer independently predicted LOS. CONCLUSIONS: Malnutrition, low quality of life scores and being diagnosed with advanced ovarian cancer are the major determinants of prolonged LOS amongst gynecological cancer patients. Interventions addressing malnutrition and poor QOL may decrease LOS in gynecological cancer patients. SN - 1471-2407 UR - https://www.unboundmedicine.com/medline/citation/20497581/Pretreatment_malnutrition_and_quality_of_life___association_with_prolonged_length_of_hospital_stay_among_patients_with_gynecological_cancer:_a_cohort_study_ L2 - https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-10-232 DB - PRIME DP - Unbound Medicine ER -