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[Clinical and serological findings of syphilis in HIV-infected patients].
Dtsch Med Wochenschr. 1991 Jun 21; 116(25):968-72.DM

Abstract

To identify the characteristic features of lues in patients infected with HIV, 402 HIV-positive patients were examined for serological and clinical signs of lues. 141 patients (133 male, 8 female, mean age 36 [18-69] years) had a positive lues serology. Treatment for lues was required in 20 of the 141 cases (14%). In ten patients (one case of lues I, nine cases of lues II) dermatological signs were predominant, macular exanthemas (n = 4) and palmo-plantar syphilides (n = 3) being most frequent. Three patients had seropositive latent lues. Eight patients presented with signs of an active neurolues (lues II: n = 1; lues III: n = 6; lues IV: n = 1). In three of the eight cases the serum FTA-ABS-IgM findings were negative. In these three patients the need for a specific treatment was realized only on the basis of cerebrospinal fluid (CSF) examination in conjunction with the clinical findings and the anamnesis. This result makes it very clear that indication for CSF puncture should be more liberal in some HIV infected patients. The markedly high proportion of cases of neurolues (40% of the luetic patients requiring treatment) is possibly due to reactivation of old lues infections.

Authors+Show Affiliations

Interdisziplinäre HIV-Ambulanz, Allgemeines Krankenhaus St. Georg, Hamburg.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

2049984

Citation

Plettenberg, A, et al. "[Clinical and Serological Findings of Syphilis in HIV-infected Patients]." Deutsche Medizinische Wochenschrift (1946), vol. 116, no. 25, 1991, pp. 968-72.
Plettenberg A, Bahlmann W, Stoehr A, et al. [Clinical and serological findings of syphilis in HIV-infected patients]. Dtsch Med Wochenschr. 1991;116(25):968-72.
Plettenberg, A., Bahlmann, W., Stoehr, A., & Meigel, W. (1991). [Clinical and serological findings of syphilis in HIV-infected patients]. Deutsche Medizinische Wochenschrift (1946), 116(25), 968-72.
Plettenberg A, et al. [Clinical and Serological Findings of Syphilis in HIV-infected Patients]. Dtsch Med Wochenschr. 1991 Jun 21;116(25):968-72. PubMed PMID: 2049984.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical and serological findings of syphilis in HIV-infected patients]. AU - Plettenberg,A, AU - Bahlmann,W, AU - Stoehr,A, AU - Meigel,W, PY - 1991/6/21/pubmed PY - 1991/6/21/medline PY - 1991/6/21/entrez SP - 968 EP - 72 JF - Deutsche medizinische Wochenschrift (1946) JO - Dtsch Med Wochenschr VL - 116 IS - 25 N2 - To identify the characteristic features of lues in patients infected with HIV, 402 HIV-positive patients were examined for serological and clinical signs of lues. 141 patients (133 male, 8 female, mean age 36 [18-69] years) had a positive lues serology. Treatment for lues was required in 20 of the 141 cases (14%). In ten patients (one case of lues I, nine cases of lues II) dermatological signs were predominant, macular exanthemas (n = 4) and palmo-plantar syphilides (n = 3) being most frequent. Three patients had seropositive latent lues. Eight patients presented with signs of an active neurolues (lues II: n = 1; lues III: n = 6; lues IV: n = 1). In three of the eight cases the serum FTA-ABS-IgM findings were negative. In these three patients the need for a specific treatment was realized only on the basis of cerebrospinal fluid (CSF) examination in conjunction with the clinical findings and the anamnesis. This result makes it very clear that indication for CSF puncture should be more liberal in some HIV infected patients. The markedly high proportion of cases of neurolues (40% of the luetic patients requiring treatment) is possibly due to reactivation of old lues infections. SN - 0012-0472 UR - https://www.unboundmedicine.com/medline/citation/2049984/[Clinical_and_serological_findings_of_syphilis_in_HIV_infected_patients]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2008-1063704 DB - PRIME DP - Unbound Medicine ER -