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Dietary fiber, source foods and colorectal cancer risk: the Fukuoka Colorectal Cancer Study.
Scand J Gastroenterol 2010; 45(10):1223-31SJ

Abstract

OBJECTIVE

Despite much evidence from laboratory work, epidemiological evidence remains elusive regarding the role of dietary fiber in colorectal carcinogenesis. We investigated associations of dietary fiber and source foods with colorectal cancer risk in the Fukuoka Colorectal Cancer Study, a community-based case-control study.

MATERIAL AND METHODS

The study subjects were 816 incident cases of colorectal cancer and 815 community controls. Nutrient and food intakes were estimated on the basis of a computer-assisted interview regarding 148 dietary items. Odds ratios of colorectal cancer according to quintile categories of energy-adjusted intakes of dietary fiber and food groups were obtained with adjustment for non-dietary factors and dietary intakes of calcium and n-3 fatty acids.

RESULTS

Total, soluble and insoluble dietary fibers were not measurably associated with overall risk or subsite-specific risk of colorectal cancer. By contrast, rice consumption was associated with a decreased risk of colorectal cancer (trend p = 0.03), particularly of distal colon and rectal cancer (trend p = 0.02), and high intake of non-rice cereals tended to be related to an increased risk of colon cancer (trend p = 0.07). There was no association between vegetable consumption and colorectal cancer, whereas individuals with the lowest intake of fruits tended to have an increased risk of colorectal cancer.

CONCLUSIONS

The present study did not corroborate a protective association between dietary fiber and colorectal cancer, but suggested a decreased risk of distal colorectal cancer associated with rice consumption.

Authors+Show Affiliations

Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20500015

Citation

Uchida, Kazuhiro, et al. "Dietary Fiber, Source Foods and Colorectal Cancer Risk: the Fukuoka Colorectal Cancer Study." Scandinavian Journal of Gastroenterology, vol. 45, no. 10, 2010, pp. 1223-31.
Uchida K, Kono S, Yin G, et al. Dietary fiber, source foods and colorectal cancer risk: the Fukuoka Colorectal Cancer Study. Scand J Gastroenterol. 2010;45(10):1223-31.
Uchida, K., Kono, S., Yin, G., Toyomura, K., Nagano, J., Mizoue, T., ... Terasaka, R. (2010). Dietary fiber, source foods and colorectal cancer risk: the Fukuoka Colorectal Cancer Study. Scandinavian Journal of Gastroenterology, 45(10), pp. 1223-31. doi:10.3109/00365521.2010.492528.
Uchida K, et al. Dietary Fiber, Source Foods and Colorectal Cancer Risk: the Fukuoka Colorectal Cancer Study. Scand J Gastroenterol. 2010;45(10):1223-31. PubMed PMID: 20500015.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary fiber, source foods and colorectal cancer risk: the Fukuoka Colorectal Cancer Study. AU - Uchida,Kazuhiro, AU - Kono,Suminori, AU - Yin,Guang, AU - Toyomura,Kengo, AU - Nagano,Jun, AU - Mizoue,Tetsuya, AU - Mibu,Ryuichi, AU - Tanaka,Masao, AU - Kakeji,Yoshihiro, AU - Maehara,Yoshihiko, AU - Okamura,Takeshi, AU - Ikejiri,Koji, AU - Futami,Kitaroh, AU - Maekawa,Takafumi, AU - Yasunami,Yohichi, AU - Takenaka,Kenji, AU - Ichimiya,Hitoshi, AU - Terasaka,Reiji, PY - 2010/5/27/entrez PY - 2010/5/27/pubmed PY - 2011/1/29/medline SP - 1223 EP - 31 JF - Scandinavian journal of gastroenterology JO - Scand. J. Gastroenterol. VL - 45 IS - 10 N2 - OBJECTIVE: Despite much evidence from laboratory work, epidemiological evidence remains elusive regarding the role of dietary fiber in colorectal carcinogenesis. We investigated associations of dietary fiber and source foods with colorectal cancer risk in the Fukuoka Colorectal Cancer Study, a community-based case-control study. MATERIAL AND METHODS: The study subjects were 816 incident cases of colorectal cancer and 815 community controls. Nutrient and food intakes were estimated on the basis of a computer-assisted interview regarding 148 dietary items. Odds ratios of colorectal cancer according to quintile categories of energy-adjusted intakes of dietary fiber and food groups were obtained with adjustment for non-dietary factors and dietary intakes of calcium and n-3 fatty acids. RESULTS: Total, soluble and insoluble dietary fibers were not measurably associated with overall risk or subsite-specific risk of colorectal cancer. By contrast, rice consumption was associated with a decreased risk of colorectal cancer (trend p = 0.03), particularly of distal colon and rectal cancer (trend p = 0.02), and high intake of non-rice cereals tended to be related to an increased risk of colon cancer (trend p = 0.07). There was no association between vegetable consumption and colorectal cancer, whereas individuals with the lowest intake of fruits tended to have an increased risk of colorectal cancer. CONCLUSIONS: The present study did not corroborate a protective association between dietary fiber and colorectal cancer, but suggested a decreased risk of distal colorectal cancer associated with rice consumption. SN - 1502-7708 UR - https://www.unboundmedicine.com/medline/citation/20500015/Dietary_fiber_source_foods_and_colorectal_cancer_risk:_the_Fukuoka_Colorectal_Cancer_Study_ L2 - http://www.tandfonline.com/doi/full/10.3109/00365521.2010.492528 DB - PRIME DP - Unbound Medicine ER -