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Endoscopic sinus surgery improves olfaction in nasal polyposis, a multi-center study.
Rhinology. 2010 Jun; 48(2):150-5.R

Abstract

BACKGROUND

A positive effect of Endoscopic Sinus Surgery (ESS) as sole treatment on olfactory thresholds and sense of smell in patients with nasal polyposis has been questioned. The aim of this study was to test the hypothesis that ESS has a positive effect on sense of smell and olfactory threshold in nasal polyposis.

METHODS

Uncontrolled post-hoc analysis of a prospective study of 160 patients, > or = 18 years, with bilateral nasal polyps that underwent ESS to treat bilateral nasal polyposis. The effect of ESS was assessed with an olfactory threshold test, a diary score and a smell and taste score, pre-, and post-ESS.

RESULTS

All three effect measures were improved from pre-ESS to post-ESS. Olfactory threshold increased from 0.0 pre-ESS to 3.0 (p < 0.001), two weeks after surgery, and the smell diary score decreased from 3.0 to 1.7 during the same period (p < 0.001), i.e. improvement. The smell and taste score increased from 1.0 pre-ESS to 2.0 post-ESS (p = 0.002). Overall, the results were similar for patients with and without previous surgery, as well as for men and women.

CONCLUSION

ESS without concomitant medical therapy seems to improve both sense of smell and olfactory thresholds in patients with nasal polyposis in the short term.

Authors+Show Affiliations

Department of Clinical Sciences, Intervention and Technology, Division of Otorhinolaryngology, Karolinska Institutet, Karolinska University Hospital Huddinge, Sockholm, Sweden. petter.olsson@ki.seNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20502751

Citation

Olsson, Petter, and Pär Stjärne. "Endoscopic Sinus Surgery Improves Olfaction in Nasal Polyposis, a Multi-center Study." Rhinology, vol. 48, no. 2, 2010, pp. 150-5.
Olsson P, Stjärne P. Endoscopic sinus surgery improves olfaction in nasal polyposis, a multi-center study. Rhinology. 2010;48(2):150-5.
Olsson, P., & Stjärne, P. (2010). Endoscopic sinus surgery improves olfaction in nasal polyposis, a multi-center study. Rhinology, 48(2), 150-5. https://doi.org/10.4193/Rhin09.097
Olsson P, Stjärne P. Endoscopic Sinus Surgery Improves Olfaction in Nasal Polyposis, a Multi-center Study. Rhinology. 2010;48(2):150-5. PubMed PMID: 20502751.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endoscopic sinus surgery improves olfaction in nasal polyposis, a multi-center study. AU - Olsson,Petter, AU - Stjärne,Pär, PY - 2010/5/27/entrez PY - 2010/5/27/pubmed PY - 2010/8/14/medline SP - 150 EP - 5 JF - Rhinology JO - Rhinology VL - 48 IS - 2 N2 - BACKGROUND: A positive effect of Endoscopic Sinus Surgery (ESS) as sole treatment on olfactory thresholds and sense of smell in patients with nasal polyposis has been questioned. The aim of this study was to test the hypothesis that ESS has a positive effect on sense of smell and olfactory threshold in nasal polyposis. METHODS: Uncontrolled post-hoc analysis of a prospective study of 160 patients, > or = 18 years, with bilateral nasal polyps that underwent ESS to treat bilateral nasal polyposis. The effect of ESS was assessed with an olfactory threshold test, a diary score and a smell and taste score, pre-, and post-ESS. RESULTS: All three effect measures were improved from pre-ESS to post-ESS. Olfactory threshold increased from 0.0 pre-ESS to 3.0 (p < 0.001), two weeks after surgery, and the smell diary score decreased from 3.0 to 1.7 during the same period (p < 0.001), i.e. improvement. The smell and taste score increased from 1.0 pre-ESS to 2.0 post-ESS (p = 0.002). Overall, the results were similar for patients with and without previous surgery, as well as for men and women. CONCLUSION: ESS without concomitant medical therapy seems to improve both sense of smell and olfactory thresholds in patients with nasal polyposis in the short term. SN - 0300-0729 UR - https://www.unboundmedicine.com/medline/citation/20502751/Endoscopic_sinus_surgery_improves_olfaction_in_nasal_polyposis_a_multi_center_study_ L2 - https://www.rhinologyjournal.com/Abstract.php?id=870 DB - PRIME DP - Unbound Medicine ER -