Tags

Type your tag names separated by a space and hit enter

Enantioselective organocatalytic phospha-Michael reaction of alpha,beta-unsaturated ketones.
Chem Commun (Camb). 2010 Jul 14; 46(26):4806-8.CC

Abstract

Enantioselective organocatalytic phospha-Michael reaction of alpha,beta-unsaturated ketones and diaryl phosphine oxides has been developed for the first time employing multifunctional organocatalysts. Optically active products bearing quaternary chiral carbon stereocenters were obtained in high yields with good to excellent enantioselectivities (up to 98% ee).

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Wen S
Engineering Research Centre of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
Li P
No affiliation info available
Wu H
No affiliation info available
Yu F
No affiliation info available
Liang X
No affiliation info available
Ye J
No affiliation info available

MeSH

CatalysisCrystallography, X-RayKetonesMolecular ConformationOxidesPhosphinesStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20502785

Citation

Wen, Shigang, et al. "Enantioselective Organocatalytic phospha-Michael Reaction of Alpha,beta-unsaturated Ketones." Chemical Communications (Cambridge, England), vol. 46, no. 26, 2010, pp. 4806-8.
Wen S, Li P, Wu H, et al. Enantioselective organocatalytic phospha-Michael reaction of alpha,beta-unsaturated ketones. Chem Commun (Camb). 2010;46(26):4806-8.
Wen, S., Li, P., Wu, H., Yu, F., Liang, X., & Ye, J. (2010). Enantioselective organocatalytic phospha-Michael reaction of alpha,beta-unsaturated ketones. Chemical Communications (Cambridge, England), 46(26), 4806-8. https://doi.org/10.1039/c0cc00094a
Wen S, et al. Enantioselective Organocatalytic phospha-Michael Reaction of Alpha,beta-unsaturated Ketones. Chem Commun (Camb). 2010 Jul 14;46(26):4806-8. PubMed PMID: 20502785.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Enantioselective organocatalytic phospha-Michael reaction of alpha,beta-unsaturated ketones. AU - Wen,Shigang, AU - Li,Pengfei, AU - Wu,Haibo, AU - Yu,Feng, AU - Liang,Xinmiao, AU - Ye,Jinxing, Y1 - 2010/05/25/ PY - 2010/5/27/entrez PY - 2010/5/27/pubmed PY - 2010/9/30/medline SP - 4806 EP - 8 JF - Chemical communications (Cambridge, England) JO - Chem Commun (Camb) VL - 46 IS - 26 N2 - Enantioselective organocatalytic phospha-Michael reaction of alpha,beta-unsaturated ketones and diaryl phosphine oxides has been developed for the first time employing multifunctional organocatalysts. Optically active products bearing quaternary chiral carbon stereocenters were obtained in high yields with good to excellent enantioselectivities (up to 98% ee). SN - 1364-548X UR - https://www.unboundmedicine.com/medline/citation/20502785/Enantioselective_organocatalytic_phospha_Michael_reaction_of_alphabeta_unsaturated_ketones_ L2 - https://doi.org/10.1039/c0cc00094a DB - PRIME DP - Unbound Medicine ER -