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[Association of risk factors for cardiovascular disease and the rate of glomerular filtration: a cross-sectional study in the population from certain areas of Beijing].
Zhonghua Liu Xing Bing Xue Za Zhi. 2010 Mar; 31(3):256-9.ZL

Abstract

OBJECTIVE

Data from several large prospective studies revealed that a low glomerular filtration rate was independently associated with cardiovascular disease (CVD) events and all-cause mortality in high-risk populations. Much on the association was explained by traditional CVD risk factors. However, findings from population-based studies were scarce and inconsistent. We explored the correlation between risks factors of cardiovascular and chronic kidney disease (CKD) in a general population from certain area of Beijing.

METHODS

A population-based cross-sectional survey was conducted during Sep. 2007 to Oct. 2008 in Beijing. Out of 5100 individuals who were selected, 4515 met the inclusion criteria and responded to the investigation. By face to face interview, a questionnaire was used to find out the risk factors of cardiovascular disease. Body height, body weight and blood pressures were measured. Serum creatinine and total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) were detected. Glomerular filtration rate through using the Modification of Diet in Renal Disease equation was estimated. Participants were grouped into three: >/= 90, 60 - 89, < 60 [mlxmin(-1)x(1.73 m(2))(-1)] by eGFR. Univariate and multivariate logistic regression models were used to identify the associated risk factors.

RESULTS

Exposure rate of cardiovascular disease risk factors increased along with the decrease of level of eGFR. Data from univariate logistic regression analyses suggested that age, smoking, history of hypertension and diabetes, BMI, SBP, LDL-C and TG were risk factors of CKD while results from multiple logistic regression indicated that age, smoking, hypertension, high level of TG appeared to be independent risk factors of CKD.

CONCLUSION

Exposure rate of cardiovascular disease risk factors increased along with the decrease of level of eGFR while age, hypertension, high level of TG and smoking were independent risk factors of CKD.

Authors+Show Affiliations

Department of Geriatric Cardiology, The Chinese PLA General Hospital, Beijing 100853, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

20510047

Citation

Wang, Fan, et al. "[Association of Risk Factors for Cardiovascular Disease and the Rate of Glomerular Filtration: a Cross-sectional Study in the Population From Certain Areas of Beijing]." Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, vol. 31, no. 3, 2010, pp. 256-9.
Wang F, Ye P, Xiao WK, et al. [Association of risk factors for cardiovascular disease and the rate of glomerular filtration: a cross-sectional study in the population from certain areas of Beijing]. Zhonghua Liu Xing Bing Xue Za Zhi. 2010;31(3):256-9.
Wang, F., Ye, P., Xiao, W. K., Luo, L. M., & Wu, H. M. (2010). [Association of risk factors for cardiovascular disease and the rate of glomerular filtration: a cross-sectional study in the population from certain areas of Beijing]. Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, 31(3), 256-9.
Wang F, et al. [Association of Risk Factors for Cardiovascular Disease and the Rate of Glomerular Filtration: a Cross-sectional Study in the Population From Certain Areas of Beijing]. Zhonghua Liu Xing Bing Xue Za Zhi. 2010;31(3):256-9. PubMed PMID: 20510047.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Association of risk factors for cardiovascular disease and the rate of glomerular filtration: a cross-sectional study in the population from certain areas of Beijing]. AU - Wang,Fan, AU - Ye,Ping, AU - Xiao,Wen-kai, AU - Luo,Lei-ming, AU - Wu,Hong-mei, PY - 2010/6/1/entrez PY - 2010/6/1/pubmed PY - 2013/3/21/medline SP - 256 EP - 9 JF - Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi JO - Zhonghua Liu Xing Bing Xue Za Zhi VL - 31 IS - 3 N2 - OBJECTIVE: Data from several large prospective studies revealed that a low glomerular filtration rate was independently associated with cardiovascular disease (CVD) events and all-cause mortality in high-risk populations. Much on the association was explained by traditional CVD risk factors. However, findings from population-based studies were scarce and inconsistent. We explored the correlation between risks factors of cardiovascular and chronic kidney disease (CKD) in a general population from certain area of Beijing. METHODS: A population-based cross-sectional survey was conducted during Sep. 2007 to Oct. 2008 in Beijing. Out of 5100 individuals who were selected, 4515 met the inclusion criteria and responded to the investigation. By face to face interview, a questionnaire was used to find out the risk factors of cardiovascular disease. Body height, body weight and blood pressures were measured. Serum creatinine and total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) were detected. Glomerular filtration rate through using the Modification of Diet in Renal Disease equation was estimated. Participants were grouped into three: >/= 90, 60 - 89, < 60 [mlxmin(-1)x(1.73 m(2))(-1)] by eGFR. Univariate and multivariate logistic regression models were used to identify the associated risk factors. RESULTS: Exposure rate of cardiovascular disease risk factors increased along with the decrease of level of eGFR. Data from univariate logistic regression analyses suggested that age, smoking, history of hypertension and diabetes, BMI, SBP, LDL-C and TG were risk factors of CKD while results from multiple logistic regression indicated that age, smoking, hypertension, high level of TG appeared to be independent risk factors of CKD. CONCLUSION: Exposure rate of cardiovascular disease risk factors increased along with the decrease of level of eGFR while age, hypertension, high level of TG and smoking were independent risk factors of CKD. SN - 0254-6450 UR - https://www.unboundmedicine.com/medline/citation/20510047/[Association_of_risk_factors_for_cardiovascular_disease_and_the_rate_of_glomerular_filtration:_a_cross_sectional_study_in_the_population_from_certain_areas_of_Beijing]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0254-6450&amp;year=2010&amp;vol=31&amp;issue=3&amp;fpage=256 DB - PRIME DP - Unbound Medicine ER -