Abstract
INTRODUCTION
Oral candidiasis is one of the most common opportunistic oral fungal infections. Oral candidal carriage in schoolchildren is a subject of increasing interest worldwide and has recently been associated with increased caries incidence in children.
AIMS
This study was carried out to identify association between oral candidal carriage in children and dental caries.
SUBJECTS AND METHODS
One hundred subjects with an age range between 6 and 12 years were included in this study. The subjects were distributed equally into two groups, i.e., study (caries-positive) and control (caries-free) groups. Oral hygiene index and DMFT/dmft scores were recorded for each subject. Sampling for Candida was carried out using intraoral swabs and concentrated oral rinse. Sabouraud dextrose agar containing 0.1 mg/ml of chloramphenicol was used as the primary culture medium. Candida was identified by employing API-20C AUX and germ tube formation tests.
RESULTS
The subjects in the caries-positive group showed a high frequency of oral candidal carriage compared to the caries-free subjects and the results were statistically very significant (p < 0.01). The odds ratio was 67.37, implying a high caries risk with positive oral candidal carriage (95% CI 14-323).
DISCUSSION
The findings of this study underscore the possible association of Candida with dental caries.
CONCLUSIONS
The occurrence of dental caries in children with mixed dentition is positively correlated with the frequency of oral candidal carriage.
TY - JOUR
T1 - Association of oral candidal carriage with dental caries in children.
AU - Raja,M,
AU - Hannan,A,
AU - Ali,K,
Y1 - 2010/05/27/
PY - 2009/05/05/received
PY - 2010/02/25/accepted
PY - 2010/6/3/entrez
PY - 2010/6/3/pubmed
PY - 2010/11/3/medline
SP - 272
EP - 6
JF - Caries research
JO - Caries Res
VL - 44
IS - 3
N2 - INTRODUCTION: Oral candidiasis is one of the most common opportunistic oral fungal infections. Oral candidal carriage in schoolchildren is a subject of increasing interest worldwide and has recently been associated with increased caries incidence in children. AIMS: This study was carried out to identify association between oral candidal carriage in children and dental caries. SUBJECTS AND METHODS: One hundred subjects with an age range between 6 and 12 years were included in this study. The subjects were distributed equally into two groups, i.e., study (caries-positive) and control (caries-free) groups. Oral hygiene index and DMFT/dmft scores were recorded for each subject. Sampling for Candida was carried out using intraoral swabs and concentrated oral rinse. Sabouraud dextrose agar containing 0.1 mg/ml of chloramphenicol was used as the primary culture medium. Candida was identified by employing API-20C AUX and germ tube formation tests. RESULTS: The subjects in the caries-positive group showed a high frequency of oral candidal carriage compared to the caries-free subjects and the results were statistically very significant (p < 0.01). The odds ratio was 67.37, implying a high caries risk with positive oral candidal carriage (95% CI 14-323). DISCUSSION: The findings of this study underscore the possible association of Candida with dental caries. CONCLUSIONS: The occurrence of dental caries in children with mixed dentition is positively correlated with the frequency of oral candidal carriage.
SN - 1421-976X
UR - https://www.unboundmedicine.com/medline/citation/20516688/Association_of_oral_candidal_carriage_with_dental_caries_in_children_
L2 - https://www.karger.com?DOI=10.1159/000314675
DB - PRIME
DP - Unbound Medicine
ER -
