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Association of oral candidal carriage with dental caries in children.
Caries Res. 2010; 44(3):272-6.CR

Abstract

INTRODUCTION

Oral candidiasis is one of the most common opportunistic oral fungal infections. Oral candidal carriage in schoolchildren is a subject of increasing interest worldwide and has recently been associated with increased caries incidence in children.

AIMS

This study was carried out to identify association between oral candidal carriage in children and dental caries.

SUBJECTS AND METHODS

One hundred subjects with an age range between 6 and 12 years were included in this study. The subjects were distributed equally into two groups, i.e., study (caries-positive) and control (caries-free) groups. Oral hygiene index and DMFT/dmft scores were recorded for each subject. Sampling for Candida was carried out using intraoral swabs and concentrated oral rinse. Sabouraud dextrose agar containing 0.1 mg/ml of chloramphenicol was used as the primary culture medium. Candida was identified by employing API-20C AUX and germ tube formation tests.

RESULTS

The subjects in the caries-positive group showed a high frequency of oral candidal carriage compared to the caries-free subjects and the results were statistically very significant (p < 0.01). The odds ratio was 67.37, implying a high caries risk with positive oral candidal carriage (95% CI 14-323).

DISCUSSION

The findings of this study underscore the possible association of Candida with dental caries.

CONCLUSIONS

The occurrence of dental caries in children with mixed dentition is positively correlated with the frequency of oral candidal carriage.

Authors+Show Affiliations

University of Health Sciences, Lahore, Pakistan. drmahwishraja@hotmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20516688

Citation

Raja, M, et al. "Association of Oral Candidal Carriage With Dental Caries in Children." Caries Research, vol. 44, no. 3, 2010, pp. 272-6.
Raja M, Hannan A, Ali K. Association of oral candidal carriage with dental caries in children. Caries Res. 2010;44(3):272-6.
Raja, M., Hannan, A., & Ali, K. (2010). Association of oral candidal carriage with dental caries in children. Caries Research, 44(3), 272-6. https://doi.org/10.1159/000314675
Raja M, Hannan A, Ali K. Association of Oral Candidal Carriage With Dental Caries in Children. Caries Res. 2010;44(3):272-6. PubMed PMID: 20516688.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association of oral candidal carriage with dental caries in children. AU - Raja,M, AU - Hannan,A, AU - Ali,K, Y1 - 2010/05/27/ PY - 2009/05/05/received PY - 2010/02/25/accepted PY - 2010/6/3/entrez PY - 2010/6/3/pubmed PY - 2010/11/3/medline SP - 272 EP - 6 JF - Caries research JO - Caries Res VL - 44 IS - 3 N2 - INTRODUCTION: Oral candidiasis is one of the most common opportunistic oral fungal infections. Oral candidal carriage in schoolchildren is a subject of increasing interest worldwide and has recently been associated with increased caries incidence in children. AIMS: This study was carried out to identify association between oral candidal carriage in children and dental caries. SUBJECTS AND METHODS: One hundred subjects with an age range between 6 and 12 years were included in this study. The subjects were distributed equally into two groups, i.e., study (caries-positive) and control (caries-free) groups. Oral hygiene index and DMFT/dmft scores were recorded for each subject. Sampling for Candida was carried out using intraoral swabs and concentrated oral rinse. Sabouraud dextrose agar containing 0.1 mg/ml of chloramphenicol was used as the primary culture medium. Candida was identified by employing API-20C AUX and germ tube formation tests. RESULTS: The subjects in the caries-positive group showed a high frequency of oral candidal carriage compared to the caries-free subjects and the results were statistically very significant (p < 0.01). The odds ratio was 67.37, implying a high caries risk with positive oral candidal carriage (95% CI 14-323). DISCUSSION: The findings of this study underscore the possible association of Candida with dental caries. CONCLUSIONS: The occurrence of dental caries in children with mixed dentition is positively correlated with the frequency of oral candidal carriage. SN - 1421-976X UR - https://www.unboundmedicine.com/medline/citation/20516688/Association_of_oral_candidal_carriage_with_dental_caries_in_children_ L2 - https://www.karger.com?DOI=10.1159/000314675 DB - PRIME DP - Unbound Medicine ER -