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UK Food Standards Agency Workshop Report: an investigation of the relative contributions of diet and sunlight to vitamin D status.
Br J Nutr. 2010 Aug; 104(4):603-11.BJ

Abstract

The UK Food Standards Agency (FSA) convened an international group of scientific experts to review three Agency-funded projects commissioned to provide evidence for the relative contributions of two sources, dietary vitamin D intake and skin exposure to UVB rays from sunlight, to vitamin D status. This review and other emerging evidence are intended to inform any future risk assessment undertaken by the Scientific Advisory Committee on Nutrition. Evidence was presented from randomised controlled trials to quantify the amount of vitamin D required to maintain a serum 25-hydroxy vitamin D (25OHD) concentration >25 nmol/l, a threshold that is regarded internationally as defining the risk of rickets and osteomalacia. Longitudinal evidence was also provided on summer sunlight exposure required to maintain 25OHD levels above this threshold in people living in the British Isles (latitude 51 degrees-57 degrees N). Data obtained from multi-level modelling of these longitudinal datasets showed that UVB exposure (i.e. season) was the major contributor to changes in 25OHD levels; this was a consistent finding in two Caucasian groups in the north and south of the UK, but was less apparent in the one group of British women of South Asian origin living in the south of the UK. The FSA-funded research suggested that the typical daily intake of vitamin D from food contributed less than UVB exposure to average year-round 25OHD levels in both Caucasian and Asian women. The low vitamin D status of Asian women has been acknowledged for some time, but the limited seasonal variation in Asian women is a novel finding. The Workshop also considered the dilemma of balancing the risks of vitamin D deficiency (from lack of skin exposure to sunlight in summer) and skin cancer (from excessive exposure to sunlight with concomitant sunburn and erythema). Cancer Research UK advises that individuals should stay below their personal sunburn threshold to minimise their skin cancer risk. The evidence suggests that vitamin D can be produced in summer at the latitude of the UK, with minimal risk of erythema and cell damage, by exposing the skin to sunlight for a short period at midday, when the intensity of UVB is at its daily peak. The implications of the new data were discussed in the context of dietary reference values for vitamin D for the general population aged 4-64 years. Future research suggestions included further analysis of the three FSA-funded studies as well as new research.

Authors+Show Affiliations

Ashwell Associates Limited, Ashwell Street, Ashwell, Hertfordshire SG7 5PZ, UK. margaret@ashwell.uk.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Consensus Development Conference
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20522274

Citation

Ashwell, Margaret, et al. "UK Food Standards Agency Workshop Report: an Investigation of the Relative Contributions of Diet and Sunlight to Vitamin D Status." The British Journal of Nutrition, vol. 104, no. 4, 2010, pp. 603-11.
Ashwell M, Stone EM, Stolte H, et al. UK Food Standards Agency Workshop Report: an investigation of the relative contributions of diet and sunlight to vitamin D status. Br J Nutr. 2010;104(4):603-11.
Ashwell, M., Stone, E. M., Stolte, H., Cashman, K. D., Macdonald, H., Lanham-New, S., Hiom, S., Webb, A., & Fraser, D. (2010). UK Food Standards Agency Workshop Report: an investigation of the relative contributions of diet and sunlight to vitamin D status. The British Journal of Nutrition, 104(4), 603-11. https://doi.org/10.1017/S0007114510002138
Ashwell M, et al. UK Food Standards Agency Workshop Report: an Investigation of the Relative Contributions of Diet and Sunlight to Vitamin D Status. Br J Nutr. 2010;104(4):603-11. PubMed PMID: 20522274.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - UK Food Standards Agency Workshop Report: an investigation of the relative contributions of diet and sunlight to vitamin D status. AU - Ashwell,Margaret, AU - Stone,Elaine M, AU - Stolte,Heiko, AU - Cashman,Kevin D, AU - Macdonald,Helen, AU - Lanham-New,Susan, AU - Hiom,Sara, AU - Webb,Ann, AU - Fraser,David, Y1 - 2010/06/04/ PY - 2010/6/5/entrez PY - 2010/6/5/pubmed PY - 2010/9/4/medline SP - 603 EP - 11 JF - The British journal of nutrition JO - Br J Nutr VL - 104 IS - 4 N2 - The UK Food Standards Agency (FSA) convened an international group of scientific experts to review three Agency-funded projects commissioned to provide evidence for the relative contributions of two sources, dietary vitamin D intake and skin exposure to UVB rays from sunlight, to vitamin D status. This review and other emerging evidence are intended to inform any future risk assessment undertaken by the Scientific Advisory Committee on Nutrition. Evidence was presented from randomised controlled trials to quantify the amount of vitamin D required to maintain a serum 25-hydroxy vitamin D (25OHD) concentration >25 nmol/l, a threshold that is regarded internationally as defining the risk of rickets and osteomalacia. Longitudinal evidence was also provided on summer sunlight exposure required to maintain 25OHD levels above this threshold in people living in the British Isles (latitude 51 degrees-57 degrees N). Data obtained from multi-level modelling of these longitudinal datasets showed that UVB exposure (i.e. season) was the major contributor to changes in 25OHD levels; this was a consistent finding in two Caucasian groups in the north and south of the UK, but was less apparent in the one group of British women of South Asian origin living in the south of the UK. The FSA-funded research suggested that the typical daily intake of vitamin D from food contributed less than UVB exposure to average year-round 25OHD levels in both Caucasian and Asian women. The low vitamin D status of Asian women has been acknowledged for some time, but the limited seasonal variation in Asian women is a novel finding. The Workshop also considered the dilemma of balancing the risks of vitamin D deficiency (from lack of skin exposure to sunlight in summer) and skin cancer (from excessive exposure to sunlight with concomitant sunburn and erythema). Cancer Research UK advises that individuals should stay below their personal sunburn threshold to minimise their skin cancer risk. The evidence suggests that vitamin D can be produced in summer at the latitude of the UK, with minimal risk of erythema and cell damage, by exposing the skin to sunlight for a short period at midday, when the intensity of UVB is at its daily peak. The implications of the new data were discussed in the context of dietary reference values for vitamin D for the general population aged 4-64 years. Future research suggestions included further analysis of the three FSA-funded studies as well as new research. SN - 1475-2662 UR - https://www.unboundmedicine.com/medline/citation/20522274/UK_Food_Standards_Agency_Workshop_Report:_an_investigation_of_the_relative_contributions_of_diet_and_sunlight_to_vitamin_D_status_ L2 - https://www.cambridge.org/core/product/identifier/S0007114510002138/type/journal_article DB - PRIME DP - Unbound Medicine ER -