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Design and biological evaluation of biphenyl-4-carboxylic acid hydrazide-hydrazone for antimicrobial activity.
Acta Pol Pharm. 2010 May-Jun; 67(3):255-9.AP

Abstract

Seven biphenyl-4-carboxylic acid hydrazide-hydrazones have been synthesized. These hydrazone derivatives were characterized by CHN analysis, IR, and 1H NMR spectral data. All the compounds were evaluated for their in vitro antimicrobial activity against two Gram negative strains (Escherichia coli and Pseudomonas aeruginosa) and two Gram positive strains (Bacillus subtilis and Staphylococcus aureus) and fungal strain Candida albicans and Aspergillus niger All newly synthesized compounds exhibited promising results.

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Authors+Show Affiliations

Deep A
Department of Pharmaceutical Sciences, G.V.M. College of Pharmacy, Sonepat-131001, India. aakashdeep82@gmail.com
Jain S
No affiliation info available
Sharma PC
No affiliation info available
Verma P
No affiliation info available
Kumar M
No affiliation info available
Dora CP
No affiliation info available

MeSH

Anti-Bacterial AgentsAntifungal AgentsBacteriaBiphenyl CompoundsCarboxylic AcidsChromatography, Thin LayerDrug DesignFungiHydrazinesHydrazonesMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsMolecular StructureSpectroscopy, Fourier Transform InfraredStructure-Activity Relationship

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20524427

Citation

Deep, Aakash, et al. "Design and Biological Evaluation of Biphenyl-4-carboxylic Acid Hydrazide-hydrazone for Antimicrobial Activity." Acta Poloniae Pharmaceutica, vol. 67, no. 3, 2010, pp. 255-9.
Deep A, Jain S, Sharma PC, et al. Design and biological evaluation of biphenyl-4-carboxylic acid hydrazide-hydrazone for antimicrobial activity. Acta Pol Pharm. 2010;67(3):255-9.
Deep, A., Jain, S., Sharma, P. C., Verma, P., Kumar, M., & Dora, C. P. (2010). Design and biological evaluation of biphenyl-4-carboxylic acid hydrazide-hydrazone for antimicrobial activity. Acta Poloniae Pharmaceutica, 67(3), 255-9.
Deep A, et al. Design and Biological Evaluation of Biphenyl-4-carboxylic Acid Hydrazide-hydrazone for Antimicrobial Activity. Acta Pol Pharm. 2010 May-Jun;67(3):255-9. PubMed PMID: 20524427.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Design and biological evaluation of biphenyl-4-carboxylic acid hydrazide-hydrazone for antimicrobial activity. AU - Deep,Aakash, AU - Jain,Sandeep, AU - Sharma,Prabodh Chander, AU - Verma,Prabhakar, AU - Kumar,Mahesh, AU - Dora,Chander Parkash, PY - 2010/6/8/entrez PY - 2010/6/9/pubmed PY - 2010/6/25/medline SP - 255 EP - 9 JF - Acta poloniae pharmaceutica JO - Acta Pol Pharm VL - 67 IS - 3 N2 - Seven biphenyl-4-carboxylic acid hydrazide-hydrazones have been synthesized. These hydrazone derivatives were characterized by CHN analysis, IR, and 1H NMR spectral data. All the compounds were evaluated for their in vitro antimicrobial activity against two Gram negative strains (Escherichia coli and Pseudomonas aeruginosa) and two Gram positive strains (Bacillus subtilis and Staphylococcus aureus) and fungal strain Candida albicans and Aspergillus niger All newly synthesized compounds exhibited promising results. SN - 0001-6837 UR - https://www.unboundmedicine.com/medline/citation/20524427/Design_and_biological_evaluation_of_biphenyl_4_carboxylic_acid_hydrazide_hydrazone_for_antimicrobial_activity_ L2 - http://www.ptfarm.pl/pub/File/Acta_Poloniae/2010/3/255.pdf DB - PRIME DP - Unbound Medicine ER -