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Characterization of phenolic compounds in Helichrysum melaleucum by high-performance liquid chromatography with on-line ultraviolet and mass spectrometry detection.
Rapid Commun Mass Spectrom. 2010 Jul 15; 24(13):1851-68.RC

Abstract

Helicrysum melaleucum is a medicinal plant traditionally used in the islands of the Macaronesia region for the treatment of respiratory diseases. In this work, the phenolic compounds of Helicrysum melaleucum plants collected in different geographical locations of Madeira Island and their morphological parts (total aerial parts, leaves, flowers and stems) were extracted and analyzed separately by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC-DAD/ESI-MS(n)). A total of 68 compounds were characterized based mainly on their UV and mass spectra. These included derivatives of O-glycosylated flavonoids (flavonol and flavones type), quinic acid, caffeic acid, lignans and polyphenols. The flowers were found to be the morphological part with higher variety of phenolic compounds. The large differences in the phenolic composition of plants collected from different geographical locations allowed the identification of a few components, such as pinoresinol and methoxylated flavone derivatives, likely to be useful as geographical markers. Also, these results promote further comparison of the bioactivities of the different samples analyzed. This paper marks the first report on the chemical analysis of Helichrysum melaleucum species.

Authors+Show Affiliations

Centro de Química da Madeira, Departamento de Química, Universidade da Madeira, Campus da Penteada, 9000-390 Funchal, Portugal.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20533315

Citation

Gouveia, Sandra C., and Paula C. Castilho. "Characterization of Phenolic Compounds in Helichrysum Melaleucum By High-performance Liquid Chromatography With On-line Ultraviolet and Mass Spectrometry Detection." Rapid Communications in Mass Spectrometry : RCM, vol. 24, no. 13, 2010, pp. 1851-68.
Gouveia SC, Castilho PC. Characterization of phenolic compounds in Helichrysum melaleucum by high-performance liquid chromatography with on-line ultraviolet and mass spectrometry detection. Rapid Commun Mass Spectrom. 2010;24(13):1851-68.
Gouveia, S. C., & Castilho, P. C. (2010). Characterization of phenolic compounds in Helichrysum melaleucum by high-performance liquid chromatography with on-line ultraviolet and mass spectrometry detection. Rapid Communications in Mass Spectrometry : RCM, 24(13), 1851-68. https://doi.org/10.1002/rcm.4585
Gouveia SC, Castilho PC. Characterization of Phenolic Compounds in Helichrysum Melaleucum By High-performance Liquid Chromatography With On-line Ultraviolet and Mass Spectrometry Detection. Rapid Commun Mass Spectrom. 2010 Jul 15;24(13):1851-68. PubMed PMID: 20533315.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Characterization of phenolic compounds in Helichrysum melaleucum by high-performance liquid chromatography with on-line ultraviolet and mass spectrometry detection. AU - Gouveia,Sandra C, AU - Castilho,Paula C, PY - 2010/6/10/entrez PY - 2010/6/10/pubmed PY - 2010/9/3/medline SP - 1851 EP - 68 JF - Rapid communications in mass spectrometry : RCM JO - Rapid Commun Mass Spectrom VL - 24 IS - 13 N2 - Helicrysum melaleucum is a medicinal plant traditionally used in the islands of the Macaronesia region for the treatment of respiratory diseases. In this work, the phenolic compounds of Helicrysum melaleucum plants collected in different geographical locations of Madeira Island and their morphological parts (total aerial parts, leaves, flowers and stems) were extracted and analyzed separately by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC-DAD/ESI-MS(n)). A total of 68 compounds were characterized based mainly on their UV and mass spectra. These included derivatives of O-glycosylated flavonoids (flavonol and flavones type), quinic acid, caffeic acid, lignans and polyphenols. The flowers were found to be the morphological part with higher variety of phenolic compounds. The large differences in the phenolic composition of plants collected from different geographical locations allowed the identification of a few components, such as pinoresinol and methoxylated flavone derivatives, likely to be useful as geographical markers. Also, these results promote further comparison of the bioactivities of the different samples analyzed. This paper marks the first report on the chemical analysis of Helichrysum melaleucum species. SN - 1097-0231 UR - https://www.unboundmedicine.com/medline/citation/20533315/Characterization_of_phenolic_compounds_in_Helichrysum_melaleucum_by_high_performance_liquid_chromatography_with_on_line_ultraviolet_and_mass_spectrometry_detection_ L2 - https://doi.org/10.1002/rcm.4585 DB - PRIME DP - Unbound Medicine ER -